Salvia R, Crippa S, Partelli S, Armatura G, Malleo G, Paini M, Pea A, Bassi C. Differences between main-duct and branch-duct intraductal papillary mucinous neoplasms of the pancreas. World J Gastrointest Surg 2010; 2(10): 342-346 [PMID: 21160841 DOI: 10.4240/wjgs.v2.i10.342]
Corresponding Author of This Article
Claudio Bassi, MD, Department of Surgery - Chirurgia Generale B, Policlinico “GB Rossi” Hospital, University of Verona, Piazzale LA Scuro, 10-37134 Verona, Italy. claudio.bassi@univr.it
Article-Type of This Article
Topic Highlight
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Oct 27, 2010; 2(10): 342-346 Published online Oct 27, 2010. doi: 10.4240/wjgs.v2.i10.342
Differences between main-duct and branch-duct intraductal papillary mucinous neoplasms of the pancreas
Roberto Salvia, Stefano Crippa, Stefano Partelli, Giulia Armatura, Giuseppe Malleo, Marina Paini, Antonio Pea, Claudio Bassi
Roberto Salvia, Stefano Crippa, Stefano Partelli, Giulia Armatura, Giuseppe Malleo, Marina Paini, Antonio Pea, Claudio Bassi, Department of Surgery - General Surgery B, “GB Rossi” Hospital, University of Verona, 10-37134 Verona, Italy
Author contributions: Salvia R, Crippa S, Partelli S, Paini M, Pea A and Malleo G analyzed the data; Salvia R, Crippa S and Armatura G wrote the paper; Bassi C reviewed and supervised the work.
Correspondence to: Claudio Bassi, MD, Department of Surgery - Chirurgia Generale B, Policlinico “GB Rossi” Hospital, University of Verona, Piazzale LA Scuro, 10-37134 Verona, Italy. claudio.bassi@univr.it
Telephone: +39-45-8124552 Fax: +39-045-8124826
Received: May 18, 2010 Revised: September 17, 2010 Accepted: September 24, 2010 Published online: October 27, 2010
Abstract
In the last decade, intraductal papillary mucinous neoplasms (IPMNs) have become commonly diagnosed. From a morphological standpoint, they are classified in main-duct IPMNs (MD-IPMNs) and branch-duct IPMNs (BD-IPMNs), depending on the type of involvement of the pancreatic ductal system by the neoplasm. Despite the fact that our understanding of their natural history is still incomplete, recent data indicate that MD-IPMNs and BD-IPMNs show significant differences in terms of biological behaviour with MD-IPMNs at higher risk of malignant degeneration. In the present paper, clinical and epidemiological characteristics, rates of malignancy and the natural history of MD-IPMNs and BD-IPMNs are analyzed. The profile of IPMNs involving both the main pancreatic duct and its side branches (combined-IPMNs) are also discussed. Finally, general recommendations for management based on these differences are given.
