Wang Y, Xi JW, Zhang WS, Cao ZL, Liu B, Zhao YN, Chen Y. Self-made double-lumen jejunal tube for bile reinfusion and enteral nutrition after percutaneous transhepatic cholangial drainage. World J Gastrointest Surg 2026; 18(5): 116545 [DOI: 10.4240/wjgs.v18.i5.116545]
Corresponding Author of This Article
Yong Chen, Department of Infectious Diseases, The First Affiliated Hospital of Hebei North University, No. 12 Changqing Road, Zhangjiakou 075061, Hebei Province, China. zjkyfcy0620@163.com
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Gastroenterology & Hepatology
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Wang Y, Xi JW, Zhang WS, Cao ZL, Liu B, Zhao YN, Chen Y. Self-made double-lumen jejunal tube for bile reinfusion and enteral nutrition after percutaneous transhepatic cholangial drainage. World J Gastrointest Surg 2026; 18(5): 116545 [DOI: 10.4240/wjgs.v18.i5.116545]
World J Gastrointest Surg. May 27, 2026; 18(5): 116545 Published online May 27, 2026. doi: 10.4240/wjgs.v18.i5.116545
Self-made double-lumen jejunal tube for bile reinfusion and enteral nutrition after percutaneous transhepatic cholangial drainage
Yan Wang, Jiang-Wei Xi, Wen-Shuang Zhang, Zhi-Li Cao, Bin Liu, Ya-Nan Zhao, Yong Chen
Yan Wang, Wen-Shuang Zhang, Zhi-Li Cao, Department of Infectious Diseases, The Second Affiliated Hospital of Hebei North University, Zhangjiakou 075100, Hebei Province, China
Jiang-Wei Xi, Bin Liu, Department of General Surgery, The Second Affiliated Hospital of Hebei North University, Zhangjiakou 075100, Hebei Province, China
Ya-Nan Zhao, Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Hebei North University, Zhangjiakou 075100, Hebei Province, China
Yong Chen, Department of Infectious Diseases, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075061, Hebei Province, China
Co-first authors: Yan Wang and Jiang-Wei Xi.
Author contributions: Wang Y and Xi JW were responsible for the study conception and design, data acquisition, and initial manuscript drafting, contributed equally as co-first authors; Zhang WS and Cao ZL participated in patient enrollment, clinical data collection, and follow-up management; Xi JW and Liu B were involved in the implementation of the intervention procedures and contributed to clinical data interpretation; Zhao YN assisted in data organization, statistical analysis, and result verification; Chen Y supervised the entire study and provided critical revision of the manuscript for important intellectual content. All authors read and approved the final manuscript and agree to be accountable for all aspects of the work.
Supported by Zhangjiakou Science and Technology Research and Development Program, No. 2121093D.
Institutional review board statement: This study was reviewed and approved by the Medical Ethics Committee of the Second Affiliated Hospital of Hebei North University, in accordance with the ethical standards of the Declaration of Helsinki.
Informed consent statement: The requirement for written informed consent was waived by the Medical Ethics Committee of the Second Affiliated Hospital of Hebei North University due to the retrospective nature of the study. All patient data were anonymized prior to analysis.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement:
The datasets generated and/or analyzed during the current study are available from the corresponding author upon reasonable request.
Corresponding author: Yong Chen, Department of Infectious Diseases, The First Affiliated Hospital of Hebei North University, No. 12 Changqing Road, Zhangjiakou 075061, Hebei Province, China. zjkyfcy0620@163.com
Received: December 2, 2025 Revised: January 4, 2026 Accepted: February 28, 2026 Published online: May 27, 2026 Processing time: 176 Days and 4 Hours
Abstract
BACKGROUND
Percutaneous transhepatic cholangial drainage (PTCD) effectively relieves biliary obstruction but inevitably causes bile loss, disrupting nutritional homeostasis and compromising gastrointestinal integrity.
AIM
To investigate whether a self-made double-lumen jejunal nutrition tube, which enables simultaneous bile reinfusion and enteral nutrition delivery, demonstrates superior clinical outcomes compared to conventional single-lumen enteral nutrition in PTCD patients.
METHODS
This retrospective cohort study enrolled 120 patients who underwent PTCD for obstructive jaundice between January 2019 and December 2023. Patients received either bile reinfusion combined with enteral nutrition via double-lumen jejunal tube (observation group, n = 60) or conventional single-lumen nasojejunal tube nutrition without bile reinfusion (control group, n = 60). Baseline characteristics were comparable between groups. Primary outcomes included nutritional biomarkers (serum albumin, prealbumin, transferrin) and gastrointestinal functional recovery indicators. Secondary outcomes encompassed complication rates, hospitalization duration, and patient satisfaction metrics.
RESULTS
The observation group demonstrated significantly superior outcomes across all parameters. Nutritional biomarkers showed greater improvement at postoperative days 7 and 14 (all P < 0.001). Gastrointestinal function recovery was markedly accelerated, with reduced time to first flatus (48.3 ± 8.2 hours vs 68.5 ± 12.3 hours, P < 0.001) and first defecation (72.1 ± 10.5 hours vs 96.8 ± 15.2 hours, P < 0.001). The observation group experienced a 60% relative reduction in overall complication rates (20.0% vs 50.0%, P = 0.015), 30% shorter hospital stays (10.2 ± 2.3 days vs 14.5 ± 3.1 days, P < 0.001), and significantly higher patient satisfaction scores (8.5 ± 1.2 vs 6.3 ± 1.5, P < 0.001). Multivariate analysis identified bile reinfusion as an independent predictor of treatment success (adjusted odds ratio = 9.45, 95% confidence interval: 2.31-38.67, P = 0.002).
CONCLUSION
The self-made double-lumen jejunal nutrition tube with integrated bile reinfusion significantly enhances nutritional recovery, accelerates gastrointestinal function restoration, reduces complications, shortens hospitalization, and improves patient-centered outcomes in PTCD patients, offering a safe and practical approach for postoperative management.
Core Tip: After percutaneous transhepatic cholangial drainage, bile is usually lost externally, which may compromise nutrition and gastrointestinal recovery. This study evaluated a self-made double-lumen jejunal nutrition tube that permits bile reinfusion while delivering enteral nutrition. Compared with conventional single-lumen feeding, this approach improved serum nutritional markers, hastened bowel function recovery, lowered complication rates, shortened hospital stay and increased patient satisfaction. The results support double-lumen jejunal tube–based bile reinfusion as a feasible and effective strategy for postoperative care in percutaneous transhepatic cholangial drainage patients.
