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Letter to the Editor
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Surg. Feb 27, 2026; 18(2): 114639
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.114639
Integrating traditional Chinese medicine in anal fistula surgery: A step forward in holistic patient care
Yu-Xing Liu, Chen-Ming Liu
Yu-Xing Liu, Department of General Surgery, BenQ Medical Center, Nanjing 210000, Jiangsu Province, China
Chen-Ming Liu, Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
Chen-Ming Liu, National Clinical Research Center for Digestive Diseases, Beijing 100050, China
Author contributions: Liu YX contributed to conceptualization and original draft preparation; Liu YX and Liu CM overseeing supervision, review, editing, and project administration. All authors have read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Chen-Ming Liu, Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong’an Road, Xicheng District, Beijing 100050, China. lcm945256445@163.com
Received: September 24, 2025
Revised: October 31, 2025
Accepted: December 10, 2025
Published online: February 27, 2026
Processing time: 154 Days and 23.4 Hours
Abstract

This letter comments on the retrospective cohort study by Liu et al, which evaluates the integration of traditional Chinese medicine (TCM) with conventional seton-based surgery for complex anal fistulas. The study reports a 90.0% success rate in the TCM-integrated group vs 78.8% in the conventional group, with a mean healing time reduced from 28.3 days to 21.5 days and recurrence rates of 5.0% vs 15.0%. These outcomes highlight the potential of TCM modalities - such as herbal decoctions and fumigation - to complement surgical management by addressing inflammation, pain, and tissue regeneration. While the retrospective design and single-center setting warrant cautious interpretation, this work provides a valuable foundation for future randomized trials and underscores the importance of personalized, integrative approaches in colorectal surgery. Further research should focus on standardizing TCM protocols and elucidating the underlying mechanisms of its efficacy.

Keywords: Anal fistula; Traditional Chinese medicine; Holistic care; Integrative medicine; Surgical outcomes; Personalized medicine

Core Tip: This commentary discusses the study by Liu et al, which provides evidence for integrating traditional Chinese medicine with surgery in complex anal fistula management. We emphasize how this approach aligns with holistic care principles, addressing both anatomical defects and underlying inflammatory and regenerative processes. While the study’s retrospective design limits causal inference, it highlights the potential of integrative strategies to improve clinical outcomes and patient satisfaction, paving the way for future randomized trials to standardize protocols and validate efficacy.