Yi JZ, Liu YG, Liu CY, Fang CF. Impact of autonomic nerve-oriented anatomical laparoscopic surgery on recovery in patients with colorectal cancer. World J Gastrointest Surg 2025; 17(5): 103439 [DOI: 10.4240/wjgs.v17.i5.103439]
Corresponding Author of This Article
Chuan-Fa Fang, MD, Chief Physician, Department of Gastrointestinal Hernia, People’s Hospital of Ganzhou, No. 16 Meiguan Avenue, Zhanggong District, Ganzhou 341000, Jiangxi Province, China. fangcf6113872@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Jian-Zhong Yi, Yun-Geng Liu, Chuan-Yuan Liu, Chuan-Fa Fang, Department of Gastrointestinal Hernia, People’s Hospital of Ganzhou, Ganzhou 341000, Jiangxi Province, China
Author contributions: Yi JZ designed the study; Liu YG and Liu CY contributed to data analysis; Yi JZ and Fang CF were involved in data collection and drafting the manuscript; All authors have read and approved the final manuscript submitted for publication.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of the People’s Hospital of Ganzhou City, Jiangxi Province, Ganzhou, China (No. TY-ZKY2024-150-01).
Informed consent statement: All study participants or their legal guardians provided written informed consent before recruitment.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chuan-Fa Fang, MD, Chief Physician, Department of Gastrointestinal Hernia, People’s Hospital of Ganzhou, No. 16 Meiguan Avenue, Zhanggong District, Ganzhou 341000, Jiangxi Province, China. fangcf6113872@163.com
Received: March 5, 2025 Revised: April 3, 2025 Accepted: April 25, 2025 Published online: May 27, 2025 Processing time: 78 Days and 19 Hours
Abstract
BACKGROUND
Implementation of an autonomic nerve-oriented anatomical approach in laparoscopic surgery for patients with colorectal cancer may provide a new reference for surgical intervention in this patient population.
AIM
To assess the impact of autonomic nerve-oriented anatomical laparoscopic surgery on recovery and postoperative risks in patients with colorectal cancer.
METHODS
Data from 116 patients diagnosed with colorectal cancer, treated between January 2016 and May 2024, were randomly divided into 2 groups (n = 58 each) according to surgical approach: Control (radical vessel-oriented laparoscopic surgery); and Observation (autonomic nerve-oriented anatomical surgery). Perioperative indicators, and postoperative risk for urinary dysfunction and sexual function were compared between the 2 groups.
RESULTS
Compared with the control group, the observation group experienced less intraoperative blood loss (P < 0.05) and exhibited superior perioperative indicators (P < 0.05). At 2 weeks and 3 months postoperatively, the proportion of patients with urinary dysfunction in the observation group was lower than that in the control group (P < 0.05). Four months postoperatively, there were significant differences in male erectile dysfunction, female dyspareunia, and sexual pleasure grading between the 2 groups (P < 0.05).
CONCLUSION
The autonomic nerve-oriented anatomical approach to laparoscopic surgery for colorectal cancer accelerates postoperative recovery, with decreased intraoperative blood loss, lower impact on urinary and sexual functions, and enhances surgical safety.
Core Tip: This study compared the efficacy of autonomic nerve-oriented anatomical laparoscopic surgery with that of conventional vessel-oriented laparoscopic surgery in patients diagnosed with colorectal cancer. Results indicated that the autonomic nerve-oriented approach reduced intraoperative bleeding, enhanced postoperative recovery, and decreased the risk for urinary and sexual dysfunction, thus contributing to improving surgical safety.
