Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. May 27, 2025; 17(5): 102799
Published online May 27, 2025. doi: 10.4240/wjgs.v17.i5.102799
Effect of perioperative disinfection and isolation measures in infection control after gastrointestinal surgery: A retrospective analysis
Hai-Yan Wang, Yan Zou, Li-Ya Shi, Xue Qin, Li-Juan Hong
Hai-Yan Wang, Li-Ya Shi, Xue Qin, Li-Juan Hong, Department of Nosocomial Infection Management, The First Affiliated Hospital of Hainan Medical University, Haikou 570102, Hainan Province, China
Yan Zou, Department of Anesthesia Surgery, The First Affiliated Hospital of Hainan Medical University, Haikou 570102, Hainan Province, China
Author contributions: Wang HY and Hong LJ conceived this project; Zou Y collected and analyzed data; Wang HY and Shi LY jointly wrote the initial draft of the manuscript; Qin X provided expert advice and made revisions to the manuscript; and all authors have contributed to this article and approved the submitted version.
Institutional review board statement: This study has been reviewed and approved by the Ethics Committee of the First Affiliated Hospital of Hainan Medical University (No. HYFY-2024-004).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No data available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li-Juan Hong, MD, Department of Nosocomial Infection Management, The First Affiliated Hospital of Hainan Medical University, No. 31 Longhua Road, Haikou 570102, Hainan Province, China. hongshanshui123@163.com
Received: January 8, 2025
Revised: February 17, 2025
Accepted: March 31, 2025
Published online: May 27, 2025
Processing time: 134 Days and 18.8 Hours
Abstract
BACKGROUND

The application of perioperative disinfection and isolation measures to patients undergoing gastrointestinal surgery with postoperative infection can provide a data reference for reducing the postoperative infection rate, improving postoperative biochemical markers, and enhancing postoperative recovery outcomes.

AIM

To explore the effectiveness of perioperative disinfection and isolation measures in controlling postoperative infection following gastrointestinal surgery. It also sought to compare infection rates and biochemical markers between the observation and control groups and evaluate the impact of disinfection and isolation measures on reducing postoperative complications.

METHODS

A retrospective analysis was conducted. Ninety-six patients who underwent gastrointestinal surgery between January 2022 and December 2023 were selected and divided into an observation group and a control group, with 48 cases in each. The observation group received disinfection and isolation measures during the perioperative period, whereas the control group received standard nursing care. The incidence of infection, white blood cell count, C-reactive protein levels, hemoglobin levels, and liver function markers (alanine aminotransferase, aspartate aminotransferase, creatinine, and blood urea nitrogen) were monitored postoperatively in both groups.

RESULTS

The postoperative infection rate in the observation group was significantly lower than that in the control group (P < 0.05). White blood cell and C-reactive protein levels decreased significantly after surgery in the observation group and were significantly lower than those in the control group (P < 0.05). Alanine aminotransferase, aspartate aminotransferase, creatinine, and blood urea nitrogen levels in the observation group were lower than those in the control group on postoperative days 1 and 3, showing a significant difference (P < 0.05).

CONCLUSION

Perioperative disinfection and isolation measures effectively reduce postoperative infection rates in gastrointestinal surgery patients and improve biochemical markers, thereby enhancing recovery outcomes. This study provides a valuable basis for postoperative infection control and has significant clinical applications.

Keywords: Perioperative; Disinfection and isolation measures; Gastrointestinal surgery; Postoperative infection; Postoperative recovery outcomes

Core Tip: Perioperative disinfection and isolation measures are crucial for infection control in gastrointestinal surgery. This study demonstrates that implementing these measures significantly reduces postoperative infection rates, lowers inflammatory markers (white blood cell count, C-reactive protein), and improves liver function and recovery outcomes. A comprehensive approach, including preoperative skin preparation, intraoperative aseptic techniques, and strict postoperative wound care, enhances patient safety, reduces complications, shortens hospital stays, and mitigates antibiotic resistance. Strengthening these strategies can provide valuable guidance for improving infection prevention protocols in surgical settings and optimizing postoperative recovery.