Scientometrics
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Apr 27, 2025; 17(4): 102020
Published online Apr 27, 2025. doi: 10.4240/wjgs.v17.i4.102020
Visualizing global progress and challenges in esophagogastric variceal bleeding
De-Xin Wang, Xue-Jie Wu, Jin-Zhong Yu, Jun-Yi Zhan, Fei-Fei Xing, Wei Liu, Jia-Mei Chen, Ping Liu, Cheng-Hai Liu, Yong-Ping Mu
De-Xin Wang, Jun-Yi Zhan, Fei-Fei Xing, Wei Liu, Jia-Mei Chen, Ping Liu, Cheng-Hai Liu, Yong-Ping Mu, Cell Biology Laboratory, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
De-Xin Wang, Jun-Yi Zhan, Fei-Fei Xing, Wei Liu, Jia-Mei Chen, Ping Liu, Cheng-Hai Liu, Yong-Ping Mu, Institute of Liver Diseases, Shanghai Academy of Chinese Medicine, Shanghai 201203, China
De-Xin Wang, Jun-Yi Zhan, Fei-Fei Xing, Wei Liu, Jia-Mei Chen, Ping Liu, Cheng-Hai Liu, Yong-Ping Mu, Clinical Key Laboratory of Traditional Chinese Medicine of Shanghai, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
De-Xin Wang, Jun-Yi Zhan, Fei-Fei Xing, Wei Liu, Jia-Mei Chen, Ping Liu, Cheng-Hai Liu, Yong-Ping Mu, Key Laboratory of Liver and Kidney Disease of the Ministry of Education, Shanghai 201203, China
Xue-Jie Wu, Heilongjiang University of Chinese Medicine, Harbin 150040, Heilongjiang Province, China
Jin-Zhong Yu, Department of Gastroenterology Endoscopy, Shuguang Hospital Affiliated to Shanghai University of Chinese Medicine, Shanghai 201203, China
Co-first authors: De-Xin Wang and Xue-Jie Wu.
Co-corresponding authors: Cheng-Hai Liu and Yong-Ping Mu.
Author contributions: Wang DX conceived and designed the study; Wang DX and Wu XJ participated in data processing and statistical analysis, and drafted the manuscript, they contributed equally to this article, they are the co-first authors of this manuscript; Yu JZ, Zhan JY, Xing FF contributed to data analysis and interpretation; Liu W, Chen JM, Liu P, Liu CH, Mu YP supervised the review of the study; Liu CH, Mu YP they contributed equally to this article, they are the co-corresponding authors of this manuscript; and all authors seriously revised and approved the final manuscript.
Supported by the National Natural Science Foundation of China, No. 81874390 and No. 81573948; Shanghai Natural Science Foundation, No. 21ZR1464100; Science and Technology Innovation Action Plan of Shanghai Science and Technology Commission, No. 22S11901700; and the Shanghai Key Specialty of Traditional Chinese Clinical Medicine, No. shslczdzk01201.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yong-Ping Mu, MD, PhD, Chief Physician, Cell Biology Laboratory, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, No. 528 Zhangheng Road, Pudong District, Shanghai 201203, China. ypmu8888@126.com
Received: October 5, 2024
Revised: January 20, 2025
Accepted: February 13, 2025
Published online: April 27, 2025
Processing time: 174 Days and 15.7 Hours
Abstract
BACKGROUND

Esophageal and gastric variceal bleeding is a catastrophic complication of portal hypertension, most commonly caused by cirrhosis of various etiologies. Although a considerable body of research has been conducted in this area, the complexity of the disease and the lack of standardized treatment strategies have led to fragmented findings, insufficient information, and a lack of systematic investigation. Bibliometric analysis can help clarify research trends, identify core topics, and reveal potential future directions. Therefore, this study aims to use bibliometric methods to conduct an in-depth exploration of research progress in this field, with the expectation of providing new insights for both clinical practice and scientific research.

AIM

To evaluate research trends and advancements in esophagogastric variceal bleeding (EGVB) over the past twenty years.

METHODS

Relevant publications on EGVB were retrieved from the Web of Science Core Collection. VOSviewer, Pajek, CiteSpace, and the bibliometrix package were then employed to perform bibliometric visualizations of publication volume, countries, institutions, journals, authors, keywords, and citation counts.

RESULTS

The analysis focused on original research articles and review papers. From 2004 to 2023, a total of 2097 records on EGVB were retrieved. The number of relevant publications has increased significantly over the past two decades, especially in China and the United States. The leading contributors in this field, in terms of countries, institutions, authors, and journals, were China, Assistance Publique-Hôpitaux de Paris, Bosch Jaime, and World Journal of Gastroenterology, respectively. Core keywords in this field include portal hypertension, management, liver cirrhosis, risk, prevention, and diagnosis. Future research directions may focus on optimizing diagnostic methods, personalized treatment, and multidisciplinary collaboration.

CONCLUSION

Using bibliometric methods, this study reveals the developmental trajectory and trends in research on EGVB, underscoring risk assessment and diagnostic optimization as the core areas of current focus. The study provides an innovative and systematic perspective for this field, indicating that future research could center on multidisciplinary collaboration, personalized treatment approaches, and the development of new diagnostic tools. Moreover, this work offers practical research directions for both the academic community and clinical practice, driving continued advancement in this domain.

Keywords: Esophagogastric variceal bleeding; Liver cirrhosis; Portal hypertension; Non-cirrhotic portal hypertension; Bibliometrics; Visualization

Core Tip: This study provides a comprehensive analysis of research trends in esophagogastric variceal bleeding over the past two decades through bibliometric methods. By systematically reviewing a wide range of publications, it identifies key areas of focus, particularly in risk assessment and diagnosis, which are crucial for advancing clinical decision-making. Additionally, the findings highlight the importance of emerging technologies and innovative approaches in the management of this condition. Future research directions may focus on optimizing diagnostic techniques, personalized treatment strategies, and fostering multidisciplinary collaboration to improve patient outcomes and enhance understanding of esophagogastric variceal bleeding.