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World J Gastrointest Surg. Mar 27, 2025; 17(3): 100321
Published online Mar 27, 2025. doi: 10.4240/wjgs.v17.i3.100321
Application progress of early nutrition intervention in patients with hepatocellular carcinoma after liver transplantation
Shan-Shan Deng, Yu-Ping Zhu, Zhi-Tao Chen, Wan Li
Shan-Shan Deng, Yu-Ping Zhu, Department of Medical Oncology, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International, Medical College, Hangzhou 310022, Zhejiang Province, China
Zhi-Tao Chen, Department of Hepatobiliary Pancreatic Surgery, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International, Medical College, Hangzhou 310022, Zhejiang Province, China
Wan Li, Department of Critical Care Medicine, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International, Medical College, Hangzhou 310022, Zhejiang Province, China
Co-first authors: Shan-Shan Deng and Yu-Ping Zhu.
Author contributions: Li W designed review; Chen ZT collected literature; Deng SS and Zhu YP wrote the paper, they contributed equally to this manuscript and are co-first authors.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wan Li, Department of Critical Care Medicine, Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International, Medical College, No. 848 Dongxin Road, Hangzhou 310022, Zhejiang Province, China. liwan19892024@163.com
Received: October 11, 2024
Revised: December 1, 2024
Accepted: January 9, 2025
Published online: March 27, 2025
Processing time: 135 Days and 18.3 Hours
Abstract

Liver transplantation, as an effective therapy for patients with liver cancer, plays an important role in improving the quality of life of patients. However, the complexity and trauma of liver transplantation can easily lead to the occurrence of malnutrition in patients, and then increase the risk of postoperative complications, which has aroused widespread clinical attention. Reasonable nutritional support can not only maintain the stability of the body’s internal environment, reduce the occurrence of complications, but also promote the recovery of liver and other organ functions. In recent years, with the in-depth understanding of nutritional metabolism after liver transplantation, the application of enteral nutrition and parenteral nutrition in nutritional support after liver transplantation has been increasingly extensive and achieved remarkable results. This paper discusses the effect of early postoperative nutritional intervention on patients with liver cancer and liver transplantation, and combined with its mechanism of action, can better understand the effectiveness of intervention, and provide reference for the development of scientific and reasonable nutritional support programs in clinical practice.

Keywords: Liver cancer; Liver transplantation; Postoperative intervention; Early nutrition; Research progress; Summarize

Core Tip: This paper discusses the effect of early postoperative nutritional intervention on patients with liver cancer and liver transplantation, and combined with its mechanism of action, can better understand the effectiveness of intervention, and provide reference for the development of scientific and reasonable nutritional support programs in clinical practice.