Wu Y, Zhang X, Wang GQ, Jiao Y. Clinical significance of perioperative probiotic intervention on recovery following intestinal surgery. World J Gastrointest Surg 2025; 17(2): 97503 [DOI: 10.4240/wjgs.v17.i2.97503]
Corresponding Author of This Article
Yan Jiao, PhD, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun 130021, Jilin Province, China. lagelangri1@126.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Feb 27, 2025; 17(2): 97503 Published online Feb 27, 2025. doi: 10.4240/wjgs.v17.i2.97503
Clinical significance of perioperative probiotic intervention on recovery following intestinal surgery
Yang Wu, Xin Zhang, Guan-Qiao Wang, Yan Jiao
Yang Wu, Xin Zhang, Department of Nephrology, Jilin People’s Hospital, Jilin 132000, Jilin Province, China
Guan-Qiao Wang, Department of Abdominal Tumor Surgery, Jilin Cancer Hospital, Changchun 130000, Jilin Province, China
Yan Jiao, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Author contributions: Wu Y contributed to the writing, editing of the manuscript and table; Zhang X contributed to the discussion and design of the manuscript; Wu Y, Zhang X, and Wang GQ contributed to the literature search; Jiao Y designed the overall concept and outline of the manuscript. All authors have read and approve the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan Jiao, PhD, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun 130021, Jilin Province, China. lagelangri1@126.com
Received: May 31, 2024 Revised: November 3, 2024 Accepted: December 6, 2024 Published online: February 27, 2025 Processing time: 235 Days and 20.3 Hours
Abstract
Restoring the balance of gut microbiota has emerged as a critical strategy in treating intestinal disorders, with probiotics playing a pivotal role in maintaining bacterial equilibrium. Surgical preparations, trauma, and digestive tract reconstruction associated with intestinal surgeries often disrupt the intestinal flora, prompting interest in the potential role of probiotics in postoperative recovery. Lan et al conducted a prospective randomized study on 60 patients with acute appendicitis, revealing that postoperative administration of Bacillus licheniformis capsules facilitated early resolution of inflammation and restoration of gastrointestinal motility, offering a novel therapeutic avenue for accelerated postoperative recovery. This editorial delves into the effects of perioperative probiotic supplementation on physical and intestinal recovery following surgery. Within the framework of enhanced recovery after surgery, the exploration of new probiotic supplementation strategies to mitigate surgical complications and reshape gut microbiota is particularly intriguing.
Core Tip: The application of probiotics during the perioperative period is still under clinical investigation. Through their complex mechanisms, probiotics can promote postoperative recovery of intestinal peristalsis, alleviate inflammatory responses, maintain intestinal mucosal barrier function, and expedite patient rehabilitation. Given the variability of individual intestinal microbiota and the functional differences among probiotic strains, personalized probiotic therapy stands out as a significant direction for future research in accelerated rehabilitation surgery.
