Romic I, Separovic I, Grgic D, Petrovic I, Mavrek J, Silovski H. Reducing invasiveness in liver surgery-where is the limit? World J Gastrointest Surg 2025; 17(2): 101852 [DOI: 10.4240/wjgs.v17.i2.101852]
Corresponding Author of This Article
Ivan Romic, FEBS, Consultant Physician-Scientist, Department of Surgery, University Hospital Centre Zagreb, Kispaticeva 14, Zagreb 10000, Croatia. i.romic@gmail.com
Research Domain of This Article
Surgery
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Feb 27, 2025; 17(2): 101852 Published online Feb 27, 2025. doi: 10.4240/wjgs.v17.i2.101852
Reducing invasiveness in liver surgery-where is the limit?
Ivan Romic, Ivan Separovic, Dora Grgic, Igor Petrovic, Josip Mavrek, Hrvoje Silovski
Ivan Romic, Ivan Separovic, Josip Mavrek, Department of Surgery, University Hospital Centre Zagreb, Zagreb 10000, Croatia
Dora Grgic, Department of Gastroenterology and Hepatology, University Hospital Centre Zagreb, Zagreb 10000, Croatia
Igor Petrovic, Hrvoje Silovski, Department of Hepatobiliary Surgery and Transplantation, University Hospital Center Zagreb, Zagreb 10000, Croatia
Co-first authors: Ivan Romic and Ivan Separovic.
Author contributions: Romic I and Grgic D contributed conceptualization and methodology; Silovski H and Petrovic I did review of literature; Separovic I and Mavrek J contributed to the writing, and editing the manuscript.
Conflict-of-interest statement: No conflict of interest to report.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ivan Romic, FEBS, Consultant Physician-Scientist, Department of Surgery, University Hospital Centre Zagreb, Kispaticeva 14, Zagreb 10000, Croatia. i.romic@gmail.com
Received: September 28, 2024 Revised: November 29, 2024 Accepted: December 31, 2024 Published online: February 27, 2025 Processing time: 115 Days and 20.7 Hours
Abstract
In this article, we comment on the article by Wang et al published in the recent issue of the World Journal of Gastroenterology Surgery. Most prominent advancements in liver surgery in the last two decades are related to refinements in surgical technique (extraglissonean approach) and advancements in surgical technology (laparoscopy and robotics). In this article, authors present both these aspects: Laparoscopic segmentectomy using extraglissonean approach. Furthermore, they describe segmental resections of all 8 segments which is the main novelty that can be observed in the article. By now, extraglissonean approach was thoroughly described mainly in hepatectomies or lateral sectionectomies. Various “hilar gates” are defined which allows safe liver resection by ligating Glissonean pedicles first which is then followed by parenchymal resection. We here focus on past, present and future perspectives of extraglissonean approach and laparoscopic liver resections and comment the value of the presented article.
Core Tip: Liver resections are physiologically demanding procedures and there is significant risk of serious intraoperative bleeding as well as postoperative liver failure especially in cases of major hepatectomies. Technical and technological improvements may reduce these risks and extraglissonean laparoscopic approach present most recent improvement in this field. This technique contributes to precision in liver surgery and spares liver parenchyma. However, to employ this technique, a good patient selection and through preoperative planning is required.