AlOmran HA, AlMatar B, AlMonsained M, Bojal S, Momani H, AlQahtani MS. Novel surgical approach - cadaveric inferior vena cava graft reconstruction following leiomyosarcoma resection: A case report. World J Gastrointest Surg 2025; 17(2): 101775 [DOI: 10.4240/wjgs.v17.i2.101775]
Corresponding Author of This Article
Hadeel A AlOmran, MBBS, Surgeon, Department of General Surgery, King Fahad Specialist Hospital, Ammar Bin Thabit St, Al Merikbat Neighborhood, Dammam 32253, Eastern Province, Saudi Arabia. hadeelalomran92@gmail.com
Research Domain of This Article
Surgery
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Feb 27, 2025; 17(2): 101775 Published online Feb 27, 2025. doi: 10.4240/wjgs.v17.i2.101775
Novel surgical approach - cadaveric inferior vena cava graft reconstruction following leiomyosarcoma resection: A case report
Hadeel A AlOmran, Bayan AlMatar, Mohammed AlMonsained, Shoukat Bojal, Hammam Momani, Mohammed S AlQahtani
Hadeel A AlOmran, Bayan AlMatar, Mohammed AlMonsained, Shoukat Bojal, Department of General Surgery, King Fahad Specialist Hospital, Dammam 32253, Eastern Province, Saudi Arabia
Hammam Momani, Mohammed S AlQahtani, Department of Hepatobiliary and Transplant Surgery, King Fahad Specialist Hospital, Dammam 32253, Eastern Province, Saudi Arabia
Author contributions: AlOmran HA designed the overall concept, data collection, literature review, and manuscript writing; AlMatar BA and AlMonsained M collected the data, reviewed the literature, and contributed to concept building; Bojal S and Momani H reviewed the manuscript for scientific accuracy and expert opinion; AlQahtani MS was the concept guarantor and primary surgeon.
Informed consent statement: A waiver for informed consent was obtained from King Fahad Specialist Hospital, as per the lawful regulations for the purpose of case and image publications.
Conflict-of-interest statement: The authors declare no conflicts of interest related to this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hadeel A AlOmran, MBBS, Surgeon, Department of General Surgery, King Fahad Specialist Hospital, Ammar Bin Thabit St, Al Merikbat Neighborhood, Dammam 32253, Eastern Province, Saudi Arabia. hadeelalomran92@gmail.com
Received: September 25, 2024 Revised: November 13, 2024 Accepted: December 18, 2024 Published online: February 27, 2025 Processing time: 118 Days and 11.4 Hours
Abstract
BACKGROUND
Inferior vena cava (IVC) leiomyosarcomas are rare and aggressive tumors. Complete cure depends on achieving R0 resection, which often requires circumferential resection and reconstruction. Synthetic grafts have traditionally been used when venous continuity must be restored. However, the use of cadaveric IVC grafts for reconstruction has not been widely reported.
CASE SUMMARY
Herein, we present the case of a 64-year-old woman diagnosed with an intrahepatic IVC leiomyosarcoma with local invasion. The patient responded favorably to chemotherapy and subsequently underwent an en bloc right hepatectomy, retrohepatic IVC resection, and reconstruction with an interpositional cadaveric IVC graft. Serial imaging follow-ups until 2 years after the operation showed persistent patency of the graft and no graft-related complications.
CONCLUSION
Cadaveric IVC grafts are an alternative to synthetic grafts for reconstruction, with acceptable outcomes. Larger, long-term studies are necessary to validate these findings.
Core Tip: We share our experience with an unprecedented approach using a cadaveric venous graft to reconstruct the inferior vena cava (IVC) after IVC leiomyosarcoma resection. The unavailability of a synthetic graft of an appropriate size led us to use the cadaveric graft, which showed durability and patency over a 27-month period, encouraging us to share our results.
