Liu H, Gu MJ, Xu KX, Yang XH. Effect of microenvironment theory-based nursing on prognosis in intensive care unit patients with postoperative severe acute pancreatitis. World J Gastrointest Surg 2025; 17(12): 113611 [DOI: 10.4240/wjgs.v17.i12.113611]
Corresponding Author of This Article
Xiao-Hui Yang, Associate Chief Nurse, Department of Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital), No. 9 Chongwen Road, Industrial Park, Suzhou 215131, Jiangsu Province, China. yxhxiaohui135@163.com
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Critical Care Medicine
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Randomized Controlled Trial
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Dec 27, 2025 (publication date) through Dec 25, 2025
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World Journal of Gastrointestinal Surgery
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1948-9366
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Liu H, Gu MJ, Xu KX, Yang XH. Effect of microenvironment theory-based nursing on prognosis in intensive care unit patients with postoperative severe acute pancreatitis. World J Gastrointest Surg 2025; 17(12): 113611 [DOI: 10.4240/wjgs.v17.i12.113611]
World J Gastrointest Surg. Dec 27, 2025; 17(12): 113611 Published online Dec 27, 2025. doi: 10.4240/wjgs.v17.i12.113611
Effect of microenvironment theory-based nursing on prognosis in intensive care unit patients with postoperative severe acute pancreatitis
Huan Liu, Min-Jian Gu, Kua-Xin Xu, Xiao-Hui Yang
Huan Liu, Department of Nursing, The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital), Suzhou 215131, Jiangsu Province, China
Min-Jian Gu, Kua-Xin Xu, Xiao-Hui Yang, Department of Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital), Suzhou 215131, Jiangsu Province, China
Author contributions: Liu H performed most of the experiments and wrote the manuscript; Gu MJ designed the study and corrected the manuscript; Xu KX conducted the data analysis; Yang XH served as a scientific advisor and participated in the collection of human material; all of the authors read and approved the final version of the manuscript to be published.
Institutional review board statement: This study was approved by Ethics Committee of the Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital).
Clinical trial registration statement: In this nursing study, the effect of a microenvironment theory-based nursing intervention on the postoperative recovery of patients with severe acute pancreatitis in the intensive care unit was prospectively observed. The intervention consisted exclusively of optimized nursing practices (e.g., sensory modulation, early mobilization, psychological support, and environmental comfort measures) and did not involve any additional invasive procedures or deviations from standard medical care. Therefore, it did not increase the risk beyond that associated with routine treatment. This study was reviewed and approved by the hospital’s Ethics Committee. As it is classified as a quality improvement nursing project that does not fall within the scope of an interventional clinical trial, it was not registered in the Chinese Clinical Trial Registry.
Informed consent statement: All patients gave informed consent.
Conflict-of-interest statement: No benefits in any form have been received or will be received from any commercial party directly or indirectly related to the subject of this article.
CONSORT 2010 statement: We have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Data sharing statement: The technical appendix, statistical code, and dataset are available from the corresponding author.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Hui Yang, Associate Chief Nurse, Department of Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital), No. 9 Chongwen Road, Industrial Park, Suzhou 215131, Jiangsu Province, China. yxhxiaohui135@163.com
Received: September 9, 2025 Revised: October 11, 2025 Accepted: November 11, 2025 Published online: December 27, 2025 Processing time: 106 Days and 17.8 Hours
Abstract
BACKGROUND
Patients with postoperative severe acute pancreatitis (SAP) in the intensive care unit (ICU) face complex challenges arising from physiological and microenvironmental imbalances, psychological stress, and the interaction of multiple environmental factors. Traditional nursing models inadequately address this integrated microenvironment, highlighting the need for microenvironment theory-based nursing interventions to optimize outcomes.
AIM
To evaluate the impact of a microenvironment theory-based nursing intervention model on the prognosis of patients with postoperative SAP in the ICU.
METHODS
Between January 2022 and December 2024, 106 patients with SAP who were admitted to ICU of the Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital) were randomly assigned to two groups: (1) A control group (n = 53, routine care); and (2) An observation group (n = 53, routine care plus microenvironment theory-based nursing). Postoperative recovery, psychological distress, disease severity, and complication rates were compared between groups.
RESULTS
The observation group had significantly shorter postoperative flatus, defecation, and hospital stay compared with the control group (P < 0.05). The Hamilton Depression Rating Scale (17-item) and Hamilton Anxiety Rating Scale (14-item) scores in the observation group were significantly lower than those in the control group (P < 0.05). The observation group had a lower Acute Physiology and Chronic Health Evaluation II score (P < 0.05) compared with the control group. The postoperative complication rates were 5.66% (3/53) and 18.87% (10/53) in the observation group and control group, respectively (P < 0.05).
CONCLUSION
In patients with SAP, the microenvironment theory-based nursing intervention model facilitated postoperative recovery, alleviated depression and anxiety, reduced disease severity, and decreased postoperative complications.
Core Tip: This study focuses on patients with postoperative severe acute pancreatitis in the intensive care unit and innovatively introduces the microenvironment theory into the field of nursing. Traditional nursing models have limitations in addressing the complex physiological, psychological, and environmental needs of these patients. The intervention model based on microenvironment theory comprehensively considers the physiological microenvironment (e.g., sensory stimuli, physical conditions), psychological microenvironment (alleviating anxiety, reducing psychological stress), and therapeutic microenvironment (multidisciplinary collaboration, procedural protocols). Compared with routine care alone, this approach provides more comprehensive and nuanced nursing interventions.
