Chen SY, Hu M, Feng ZB, Xu Q, Wang Y. Application of ultrasound-guided localization technology in early gastric cancer surgery and prognostic analysis. World J Gastrointest Surg 2025; 17(11): 109002 [DOI: 10.4240/wjgs.v17.i11.109002]
Corresponding Author of This Article
Ying Wang, Associate Chief Physician, Department of Ultrasound, Suzhou Municipal Hospital, No. 26 Daoqian Street, Suzhou 215000, Jiangsu Province, China. anxinkl258@163.com
Research Domain of This Article
Surgery
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Retrospective Study
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Nov 27, 2025 (publication date) through Nov 25, 2025
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Publication Name
World Journal of Gastrointestinal Surgery
ISSN
1948-9366
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Chen SY, Hu M, Feng ZB, Xu Q, Wang Y. Application of ultrasound-guided localization technology in early gastric cancer surgery and prognostic analysis. World J Gastrointest Surg 2025; 17(11): 109002 [DOI: 10.4240/wjgs.v17.i11.109002]
World J Gastrointest Surg. Nov 27, 2025; 17(11): 109002 Published online Nov 27, 2025. doi: 10.4240/wjgs.v17.i11.109002
Application of ultrasound-guided localization technology in early gastric cancer surgery and prognostic analysis
Shi-Yu Chen, Min Hu, Zhu-Bin Feng, Qing Xu, Ying Wang
Shi-Yu Chen, Min Hu, Zhu-Bin Feng, Qing Xu, Department of Ultrasonography, Affiliated Yueqing Hospital of Wenzhou Medical University, Yueqing 325600, Zhejiang Province, China
Ying Wang, Department of Ultrasound, Suzhou Municipal Hospital, Suzhou 215000, Jiangsu Province, China
Co-first authors: Shi-Yu Chen and Min Hu.
Author contributions: Chen SY and Hu M contributed equally to this work as co-first authors and were responsible for the study design, data collection, statistical analysis, and manuscript drafting; Feng ZB and Xu Q participated in patient recruitment, ultrasound procedures, and data analysis; Wang Y, as the corresponding author, supervised the study, provided critical guidance, and coordinated the research collaboration. All authors reviewed and approved the final manuscript and take responsibility for the integrity of the research.
Supported by Wenzhou Science and Technology Bureau, No. Y20240363.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the Affiliated Yueqing Hospital of Wenzhou Medical University, No. YQYY202400091.
Informed consent statement: Written informed consent was obtained from all patients or their legal guardians prior to inclusion in the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The data are not publicly available due to privacy or ethical restrictions but may be available from the corresponding author on reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ying Wang, Associate Chief Physician, Department of Ultrasound, Suzhou Municipal Hospital, No. 26 Daoqian Street, Suzhou 215000, Jiangsu Province, China. anxinkl258@163.com
Received: June 10, 2025 Revised: July 22, 2025 Accepted: September 18, 2025 Published online: November 27, 2025 Processing time: 168 Days and 0.3 Hours
Abstract
BACKGROUND
The current study was to assess the application effects of conventional surgical techniques and ultrasound-guided precise localization technology for early gastric cancer (EGC), with an emphasis on long-term survival, postoperative complications, and surgical results.
AIM
To evaluate perioperative results, postoperative complications, and long-term survival in order to conduct a thorough comparison between conventional surgical techniques and ultrasound-guided precise localization technology for the treatment of EGC.
METHODS
Of 100 EGC patients were gathered, and they were subsequently divided into two groups based on the surgical technique used: The observation group (n = 52) received surgery assisted by ultrasound-guided precise localization technology, whereas the control group (n = 48) received traditional surgical treatment. The baseline characteristics were similar between the groups. Operation time, intraoperative hemorrhage, the number of lymph nodes removed, postoperative problems, survival rate, and other surgical and postoperative parameters were compared.
RESULTS
Compared with the control group, the observation group had significantly less intraoperative blood loss (80 mL vs 120 mL, P < 0.05) and more dissected lymph nodes (28 vs 22, P < 0.05). There were fewer postoperative complications in the observation group than in the routine group (8% vs 16%, P < 0.05), hospitalization after surgery was shorter, and gastrointestinal function returned sooner. The long-term survival rates at 5 years and 3 years were significantly greater in the observation group than in the control group: 82% and 88% vs 70% and 78%, respectively (P < 0.05).
CONCLUSION
It is possible that ultrasound-guided accurate localization technology might be utilized more widely in clinical practice because it could significantly enhance the results of surgery for EGC, including reduced blood loss, better lymphadenectomy, lower complication rates, and improved survival rates. Further studies should aim to refine this technology and consider its utility in other types of oncologic surgery.
Core Tip: The ultrasound-guided accurate localization technique greatly increases the surgical effect on patients with early gastric cancer, including a clearer tumor margin, shorter operation time, reduced intraoperative blood loss, greater degree of lymph node dissection, and fewer postoperative complications. This was a retrospective study that revealed that ultrasound surgery results in better 3- and 5-year survival rates than traditional surgery does. In vivo imaging allows for improved anatomical guidance to enhance accurate tumor resection and careful lymphadenectomy. These findings indicate that ultrasound guidance should be considered a routine procedure in clinical practice to increase surgical accuracy, accelerate recovery, and increase the long-term survival of patients with early gastric cancer.
