Lin Y, Wu YL, Zou DD, Luo XL, Zhang SY. Combined gastroscopic and laparoscopic resection of gastric metastatic adenosquamous carcinoma from lung: A case report. World J Gastrointest Surg 2024; 16(9): 3065-3073 [PMID: 39351550 DOI: 10.4240/wjgs.v16.i9.3065]
Corresponding Author of This Article
Yin Lin, MD, Attending Doctor, Department of Gastroenterology, Fuding Hospital, Fujian University of Traditional Chinese Medicine, No. 22 Haichun Villa of Tongcheng Street, Fuding 355200, Fujian Province, China. 471985154@qq.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Yin Lin, Yi-Long Wu, Xiao-Long Luo, Department of Gastroenterology, Fuding Hospital, Fujian University of Traditional Chinese Medicine, Fuding 355200, Fujian Province, China
Dong-Dong Zou, Department of Proctology, Fuding Hospital, Fujian University of Traditional Chinese Medicine, Fuding 355200, Fujian Province, China
Shi-Yan Zhang, Department of Clinical Laboratory, Fuding Hospital, Fujian University of Traditional Chinese Medicine, Fuding 355200, Fujian Province, China
Co-corresponding authors: Yin Lin and Shi-Yan Zhang.
Author contributions: Lin Y wrote the manuscript, performed the endoscopic procedures and the laparoscopic surgeries; Wu YL was involved in the management of the patient; Zou DD and Luo XL reviewed the radiology and pathology images; Zhang SY reviewed the manuscript and provided critical revisions; all authors discussed the case and commented on the manuscript, read and approved the final manuscript.
Supported byThe Joint Project of Natural Science Foundation of Ningde, China, No. 2022J56.
Informed consent statement: Written informed consent was obtained from the patient. In the form, the patient gave consent for her images and other clinical information to be reported in the journal. The patient understands that her name will not be published and due efforts will be made to conceal her identity.
Conflict-of-interest statement: All authors declare no competing financial interests for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yin Lin, MD, Attending Doctor, Department of Gastroenterology, Fuding Hospital, Fujian University of Traditional Chinese Medicine, No. 22 Haichun Villa of Tongcheng Street, Fuding 355200, Fujian Province, China. 471985154@qq.com
Received: June 20, 2024 Revised: August 14, 2024 Accepted: August 22, 2024 Published online: September 27, 2024 Processing time: 89 Days and 22.5 Hours
Abstract
BACKGROUND
Primary lung cancer is the leading cause of cancer-related death worldwide. Common metastatic sites include the brain, liver, bones, and adrenal glands. However, gastric metastases from lung cancer are rare. This case may be the first report of a combined gastroscopic and laparoscopic resection for gastric metastatic adenosquamous carcinoma (ASC).
CASE SUMMARY
We report a case of gastric metastasis from lung cancer. The patient was a 61-year-old Han Chinese female who first attended our hospital complaining of a persistent cough, leading to the diagnosis of advanced-stage lung adenocarcinoma. After more than four years of chemotherapy, the patient began to experience epigastric pain. Endoscopy was performed, and pathological examination of biopsy specimens confirmed that the gastric lesion was a metastasis from lung cancer. The lesion was successfully resected by combined gastroscopy and laparoscopy. Histopathological examination of the resected gastric specimen revealed ASC.
CONCLUSION
Gastric metastases from lung cancer are rare. Endoscopy, histological and immunohistochemical staining are useful for diagnosing metastatic lesions. Surgical management may provide extended survival in appropriately selected patients.
Core Tip: We report a case of primary lung cancer that metastasized to the stomach after more than four years of chemotherapy and was successfully resected by a cooperative operation involving gastroscopy and laparoscopy. Histopathological examination of the gastric postoperative specimen revealed adenosquamous carcinoma (ASC). This may be the first report of gastric metastatic ASC from lung resected using a combinaton of gastroscopy and laparoscopy.
