Published online May 27, 2024. doi: 10.4240/wjgs.v16.i5.1354
Revised: April 7, 2024
Accepted: April 15, 2024
Published online: May 27, 2024
Processing time: 112 Days and 19.1 Hours
Previous studies have analyzed the risk factors for complications after ileostomy reversal for rectal cancer (RC), but there were significant differences in the re
To analyze the risk factors for overall complications and stoma-related complications after ileostomy reversal for patients with RC.
This was a retrospective study of 439 patients who underwent ileostomy reversal at a clinical center and were followed up between September 2012 and September 2022. Continuous variables are expressed as the mean ± SD and were analyzed with independent-sample t tests, while frequency variables are expressed as n (%), and the χ2 test or Fisher’s exact test was used. Univariate and multivariate logistic regression analyses were used to identify predictors of overall complications and stoma-related complications.
The overall complication rate after ileostomy reversal was 11.4%. Patients with lower preoperative albumin concentration (P < 0.01), greater blood loss (P = 0.017), and longer operative times (P < 0.01) were more likely to experience postoperative complications. The incidence of stoma-related complications was 6.4%. Analysis of the study showed that a higher body mass index (BMI) (P < 0.01), preoperative comorbid hypertension (P = 0.049), time from primary surgery to ileostomy reversal (P < 0.01) and longer operation time (P = 0.010) were more likely to result in stoma-related complications postoperatively. Multivariate logistic regression analysis revealed that a lower preoperative albumin level (P < 0.01, OR = 0.888, 95%CI: 0.828-0.958) was an independent risk factor for overall complications. Moreover, multivariate analysis revealed that BMI (P < 0.01, OR = 1.176, 95%CI: 1.041-1.330) and time from primary surgery to ileostomy reversal
The preoperative albumin level was a predictor of overall complications. Preoperative BMI and the time from pri
Core Tip: There were no studies that have analyzed the risk factors for stoma-related complications and overall postoperative complications after stoma reversal for rectal cancer (RC) separately. Our study showed that the preoperative serum albumin concentration was a predictor of overall complications. Preoperative body mass index and time between initial surgery and stoma reversal were predictors of stoma-related complications. Therefore, for RC patients undergoing ileostomy reversal, adequate albumin supplementation should be provided preoperatively to reduce the incidence of postoperative complications.