Clinical Trials Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Mar 27, 2024; 16(3): 816-822
Published online Mar 27, 2024. doi: 10.4240/wjgs.v16.i3.816
Clinical study of enhanced recovery after surgery in laparoscopic appendectomy for acute appendicitis
Zhu-Lin Li, Hua-Chong Ma, Yong Yang, Jian-Jun Chen, Zhen-Jun Wang
Zhu-Lin Li, Hua-Chong Ma, Yong Yang, Jian-Jun Chen, Zhen-Jun Wang, Department of General Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China
Author contributions: Li ZL, Wang ZJ and Ma HC designed the study; Li ZL and Chen JJ collected and analyzed the data; Li ZL wrote the manuscript; Yang Y and Ma HC revised the manuscript; Yang Y participated in collection of the data; All authors approved the final version of the manuscript.
Institutional review board statement: The study was reviewed and approved by the Beijing Chao-Yang Hospital’s Ethics and Medical Committee (approval No. 2018-Ke-340).
Clinical trial registration statement: This study is registered at https://www.chictr.org.cn/searchproj.html; The registration identification number is ChiCTR2400081069.
Informed consent statement: Informed consent was obtained from all patients and their families.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhen-Jun Wang, MD, Chief Physician, Director, Department of General Surgery, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing 100020, China. drzhenjun@163.com
Received: January 12, 2024
Peer-review started: January 12, 2024
First decision: January 31, 2024
Revised: February 9, 2024
Accepted: February 25, 2024
Article in press: February 25, 2024
Published online: March 27, 2024
Processing time: 70 Days and 7.3 Hours
Abstract
BACKGROUND

Enhanced recovery after surgery (ERAS) protocol is a comprehensive management modality that promotes patient recovery, especially in the patients undergoing digestive tumor surgeries. However, it is less commonly used in the appendectomy.

AIM

To study the application value of ERAS in laparoscopic surgery for acute appendicitis.

METHODS

A total of 120 patients who underwent laparoscopic appendectomy due to acute appendicitis were divided into experimental group and control group by random number table method, including 63 patients in the experimental group and 57 patients in the control group. Patients in the experimental group were managed with the ERAS protocol, and those in the control group were received the traditional treatment. The exhaust time, the hospitalization duration, the hospitalization expense and the pain score between the two groups were compared.

RESULTS

There was no significant difference in age, gender, body mass index and Sunshine Appendicitis Grading System score between the experimental group and the control group (P > 0.05). Compared to the control group, the patients in the experimental group had earlier exhaust time, shorter hospitalization time, less hospitalization cost and lower degree of pain sensation. The differences were statistically significant (P < 0.01).

CONCLUSION

ERAS could significantly accelerate the recovery of patients who underwent laparoscopic appendectomy for acute appendicitis, shorten the hospitalization time and reduce hospitalization costs. It is a safe and effective approach.

Keywords: Enhanced recovery after surgery; Appendicectomy; Laparoscopy; Acute appendicitis; Treatment

Core Tip: This study focused on the application of enhanced recovery after surgery (ERAS) in patients undergoing laparoscopic appendectomy due to acute appendicitis. Patients often suffer from considerable postoperative pain and indigestion after laparoscopic appendectomy, and approximately 10% of patients experienced postoperative complications, resulting in prolonged hospital stay and increased hospitalization costs. The value of ERAS in elective surgery has been confirmed, but there is limited research on emergency surgery. This study found that ERAS could accelerate the recovery of patients who underwent laparoscopic appendectomy due to acute appendicitis.