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World J Gastrointest Surg. Nov 27, 2024; 16(11): 3413-3424
Published online Nov 27, 2024. doi: 10.4240/wjgs.v16.i11.3413
Risk factors and prevention of pancreatic fistula after laparoscopic gastrectomy for gastric cancer
Shan-Shan Liu, Hong-Yu Xie, Hao-Dong Chang, Liang Wang, Su Yan
Shan-Shan Liu, Hong-Yu Xie, Hao-Dong Chang, Liang Wang, Su Yan, Department of Gastrointestinal Oncology Surgery, The Affiliated Hospital of Qinghai University, Xining 810000, Qinghai Province, China
Author contributions: Yan S proposed the title of the article and reviewed the manuscript; Liu SS wrote the manuscript; Xie HY and Chang HD reviewed the literature; Wang L revised the manuscript for important intellectual content; All authors read and approved the final manuscript.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Su Yan, Professor, Chief Doctor, Department of Gastrointestinal Oncology Surgery, The Affiliated Hospital of Qinghai University, No. 29 Tongren Road, Xining 810000, Qinghai Province, China. yansuxining@outlook.com
Received: April 16, 2024
Revised: August 6, 2024
Accepted: August 16, 2024
Published online: November 27, 2024
Processing time: 196 Days and 22 Hours
Abstract

Following laparoscopic gastrectomy (LG), one of the critical complications that can arise is a pancreatic fistula (PF). The inability to promptly prevent, diagnose, and manage this condition can lead to severe complications and potentially be life-threatening for the patient. The incidence of PF post-LG in gastric cancer treatment is related to factors such as surgical approach, surgical instruments, characteristics of the pancreas itself, tumor stage, and the surgeon’s experience. Currently, the diagnosis of postoperative PF is mainly based on the definition and diagnostic criteria consensus established by the International Study Group of Pancreatic Surgery. Gastrointestinal surgeons should be aware of the risk factors for PF, perform LG for gastric cancer with great care and precision, avoid pancreatic injury, and actively work to reduce the risk of postoperative PF.

Keywords: Gastric cancer; Laparoscopic surgery; Pancreatic fistula; Risk factors; Prevention

Core Tip: Pancreatic fistula after laparoscopic gastrectomy can lead to serious complications and even endanger the patient’s life. Therefore, it is of great significance to detail the risk factors connected to the onset of postoperative pancreatic fistula and to actively prevent it in order to accelerate postoperative recovery of patients and promote clinical work.