Gong YQ, Lu TL, Chen CW. Long-term survival of patients with hepatocellular carcinoma with hepatic, pulmonary, peritoneal and rare colon metastasis: A case report. World J Gastrointest Surg 2023; 15(8): 1819-1824 [PMID: 37701683 DOI: 10.4240/wjgs.v15.i8.1819]
Corresponding Author of This Article
Chao-Wu Chen, MD, PhD, Doctor, Department of Gastrointestinal Surgery, Hunan Provincial People’s Hospital, No. 61 Jiefang West Road, Furong District, Changsha 410005, Hunan Province, China. chenchaowu0@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Aug 27, 2023; 15(8): 1819-1824 Published online Aug 27, 2023. doi: 10.4240/wjgs.v15.i8.1819
Long-term survival of patients with hepatocellular carcinoma with hepatic, pulmonary, peritoneal and rare colon metastasis: A case report
Yong-Qiang Gong, Tai-Liang Lu, Chao-Wu Chen
Yong-Qiang Gong, Tai-Liang Lu, Department of Gastrointestinal Surgery, Hunan Provincial People’s Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha 410005, Hunan Province, China
Chao-Wu Chen, Department of Gastrointestinal Surgery, Hunan Provincial People’s Hospital, Changsha 410005, Hunan Province, China
Author contributions: Gong YQ collected the literature and wrote the manuscript. Lu TL supervised the manuscript. Chen CW conceived the idea and drafted the manuscript. All authors have read and approve the final manuscript.
Informed consent statement: Informed consent statement was obtained from the patient and his family for publication of this report and any accompany images.
Conflict-of-interest statement: The authors declare no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chao-Wu Chen, MD, PhD, Doctor, Department of Gastrointestinal Surgery, Hunan Provincial People’s Hospital, No. 61 Jiefang West Road, Furong District, Changsha 410005, Hunan Province, China. chenchaowu0@163.com
Received: March 11, 2023 Peer-review started: March 11, 2023 First decision: May 16, 2023 Revised: June 5, 2023 Accepted: July 7, 2023 Article in press: July 7, 2023 Published online: August 27, 2023 Processing time: 167 Days and 10.3 Hours
Abstract
BACKGROUND
Hepatocellular carcinoma (HCC) is a highly malignant cancer that often metastasizes and has a poor prognosis. Gastrointestinal tract metastases are rare, and colon metastases are even rarer. The long-term survival of patients with multiple intrahepatic and extrahepatic metastases, especially to the colon, has not been previously reported.
CASE SUMMARY
We present an atypical clinical case of a patient with liver, right lung, peritoneal, and colon metastases diagnosed successively following hepatic resection for primary HCC. Comprehensive treatment, including partial liver, lung and colon resection, palliative management such as systemic chemotherapy, trans-arterial chemoembolization, targeted therapy with sorafenib, and cryotherapy were attempted. Despite his early metastases, the patient remained relatively healthy for 8 years after diagnosis.
CONCLUSION
This case indicates that comprehensive treatment is beneficial for certain patients with metastatic HCC. Clinicians should be alert as to the possibility of rare site metastatic tumors that may be easily misdiagnosed as primary tumors.
Core Tip: Hepatocellular carcinoma (HCC) is a highly malignant cancer worldwide, which often metastasizes, but unusually to the gastrointestinal tract and particularly rare to the colon. We presented an atypical clinical case of a patient with liver, right lung, peritoneal and colon metastases diagnosed successively following hepatic resection for primary HCC. Despite his early metastases, the patient remained relatively healthy for 8 years. This case indicates that comprehensive treatment is beneficial for certain patients with metastatic HCC. Furthermore, clinicians should be alert as to the possibility of rare site metastatic tumors that may be easily misdiagnosed as primary tumors. We believe this article will be very useful to anyone who is interested in this field.
