Case Control Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Dec 27, 2023; 15(12): 2719-2726
Published online Dec 27, 2023. doi: 10.4240/wjgs.v15.i12.2719
Multidisciplinary diagnosis and treatment nutritional support intervention for gastrointestinal tumor radiotherapy: Impact on nutrition and quality of life
Lin Hui, Ying-Ying Zhang, Xiao-Dan Hu
Lin Hui, Head, Neck and Chest Radiotherapy Department 1, Affiliated Hospital of Jiangnan University, Wuxi 214000, Jiangsu Province, China
Ying-Ying Zhang, Department of Gastroenterology, The People’s Hospital of Danyang, Danyang 212300, Jiangsu Province, China
Xiao-Dan Hu, Department of Gastroenterology, Affiliated Hospital of Jiangnan University, Wuxi 214000, Jiangsu Province, China
Co-first authors: Lin Hui and Ying-Ying Zhang.
Author contributions: In this study, Hui L and Zhang YY made equal contributions as co first authors; Hu XD was designated as the corresponding author and assumed primary responsibility.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of Affiliated Hospital of Jiangnan University.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Dan Hu, MMed, Master's Student, Department of Gastroenterology, Affiliated Hospital of Jiangnan University, No. 1000 Hefeng Road, Binhu District, Wuxi 214000, Jiangsu Province, China. 258636904@qq.com
Received: August 23, 2023
Peer-review started: August 23, 2023
First decision: September 13, 2023
Revised: September 19, 2023
Accepted: November 14, 2023
Article in press: November 14, 2023
Published online: December 27, 2023
Processing time: 126 Days and 3.2 Hours
Abstract
BACKGROUND

Gastrointestinal tumors are a major cause of cancer-related deaths and have become a major public health problem. This study aims to provide a scientific basis for improving clinical treatment effects, quality of life, and prognosis of patients with gastrointestinal tumors.

AIM

To explore the clinical effect of the multidisciplinary diagnosis and treatment (MDT) nutrition intervention model on patients with gastrointestinal tumors.

METHODS

This was a case control study which included patients with gastrointestinal tumors who received radiotherapy at the Department of Oncology between January 2021 and January 2023. Using a random number table, 120 patients were randomly divided into MDT and control groups with 60 patients in each group. To analyze the effect of MDT on the nutritional status and quality of life of the patients, the nutritional status and quality of life scores of the patients were measured before and after the treatment.

RESULTS

Albumin (ALB), transferrin (TRF), hemoglobin (Hb), and total protein (TP) levels significantly decreased after the treatment. The control group had significantly lower ALB, TRF, Hb, and TP levels than the MDT group, and the differences in these levels between the two groups were statistically significant (P < 0.05). After the treatment, the MDT group had significantly more well-nourished patients than the control group (P < 0.05). The quality of life total score, somatic functioning, role functioning, and emotional functioning were higher in the MDT group than in the control group. By contrast, pain, fatigue, nausea, and vomiting scores were lower in the MDT group than in the control group (P < 0.05).

CONCLUSION

MDT nutritional intervention model effectively improves the nutritional status and quality of life of the patients. The study provides a rigorous theoretical basis for improving the prognosis of cancer patients. In the future, we intend to provide additional treatment methods for improving the quality of life of patients with cancer.

Keywords: Nutritional support; Gastrointestinal tumor; Radiotherapy; Nutrition; Quality of life; Multidisciplinary diagnosis and treatment intervention

Core Tip: The multidisciplinary diagnosis and treatment nutritional intervention model significantly improved the nutritional status and quality of life of patients with gastrointestinal tumors undergoing radiotherapy. This study provides evidence for the implementation of comprehensive nutritional support strategies to enhance treatment outcomes and patient well-being.