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Ye H, Wang Y, Zhang X, Yang L, Cai B, Zhang D, Peng B. Characterization of global research trends and prospects on celastrol, a principal bioactive ingredient of Tripterygium wilfordii Hook F: bibliometric analysis. PHARMACEUTICAL BIOLOGY 2025; 63:15-26. [PMID: 39745069 DOI: 10.1080/13880209.2024.2443424] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 04/12/2024] [Revised: 11/25/2024] [Accepted: 12/12/2024] [Indexed: 01/04/2025]
Abstract
CONTEXT Celastrol, acknowledged as a prominent exemplar of the potential for transforming traditional medicinal compounds into contemporary pharmaceuticals, has garnered considerable attention owing to its extensive pharmacological activities. The increasing volume of publications concerning celastrol highlights its importance in current scientific inquiry. Despite the growing interest in this compound, a bibliometric analysis focused on this subject remains to be undertaken. OBJECTIVE Our study explored a bibliometric approach to identify and characterize global research trends and frontiers related to celastrol, including mapping research outputs, influential contributors, and thematic areas, as well as highlighting gaps and opportunities for future investigations. MATERIALS AND METHODS In this study, we utilized the Web of Science Core Collection (WoSCC) to source and review articles related to celastrol published from 1997 to 2023. The bibliometric analysis was conducted using the R package 'Bibliometrix,' supplemented by visualization tools including CiteSpace, VOSviewer, and GraphPad Prism 10. RESULTS Celastrol related research papers have exhibited an upward trend annually and can be categorized into three distinct phases, each highlighting different areas of focus. China, the United States, and South Korea rank as the top three nations for publication volume, with varied research interests across these countries. Several prolific research teams have emerged, each with distinct areas of interest. Examining the primary research domains of celastrol (anti-inflammatory, anticancer, and toxicity) reveals a notable intersection between the first two domains. DISCUSSION AND CONCLUSIONS The scope and depth of celastrol research have been steadily expanding, with regional and team-specific variations. Key research areas include anti-inflammatory, anticancer, and toxicity studies. Future research is expected to focus on enhancing the effectiveness and reducing the toxicity of celastrol. Meanwhile, given the multi-target characteristics of celastrol's effects, integrating methods such as network biology and molecular simulation will provide a novel perspective for celastrol research.
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Affiliation(s)
- Huizi Ye
- Postgraduate training base at Shanghai Gongli Hospital, Ningxia Medical University, Shanghai, China
| | - Yufang Wang
- Postgraduate training base at Shanghai Gongli Hospital, Ningxia Medical University, Shanghai, China
| | - Xue Zhang
- Postgraduate training base at Shanghai Gongli Hospital, Ningxia Medical University, Shanghai, China
- Shanghai Health Commission Key Lab of Artificial Intelligence (AI)-Based Management of Inflammation and Chronic Diseases, Department of Central Laboratory, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China
- School of Basic Medicine, Ningxia Medical University, Yinchuan, Ningxia, China
| | - Lin Yang
- Postgraduate training base at Shanghai Gongli Hospital, Ningxia Medical University, Shanghai, China
| | - Banglan Cai
- Postgraduate training base at Shanghai Gongli Hospital, Ningxia Medical University, Shanghai, China
- School of Basic Medicine, Ningxia Medical University, Yinchuan, Ningxia, China
| | - Denghai Zhang
- Shanghai Health Commission Key Lab of Artificial Intelligence (AI)-Based Management of Inflammation and Chronic Diseases, Department of Central Laboratory, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China
| | - Bin Peng
- Shanghai Health Commission Key Lab of Artificial Intelligence (AI)-Based Management of Inflammation and Chronic Diseases, Department of Central Laboratory, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China
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Gao Y, Liu Y, Hao H. A 10-year knowledge mapping of T cells in rheumatoid arthritis: A bibliometric analysis. Hum Vaccin Immunother 2025; 21:2450855. [PMID: 39962980 PMCID: PMC11845019 DOI: 10.1080/21645515.2025.2450855] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/09/2024] [Revised: 12/31/2024] [Accepted: 01/05/2025] [Indexed: 02/23/2025] Open
Abstract
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease of autoimmune origin. T cells play crucial roles in the initiation and progression of RA. Although bibliometric methods have been widely used to synthesize knowledge trajectories across different biomedical fields, it has hardly been used to underscore the knowledge trends in relation to T cell and RA. This study used bibliometric methods to delineate the evolution of research on T cells and RA. Data were sourced from the Web of Science™ Core Collection and were scientometrically analyzed using CiteSpace and VOSviewer. From 2014 to 2023, 7037 papers on T cells and RA were retrieved. The number of annual publications is stable between 600 and 800, and the citation frequency continues to rise. The United States, China, the United Kingdom and Japan were the most productive countries. Karolinska Institute, and Harvard Medical School were the institutions that published the most research papers. Wei W, Cho ML, and Park SH were the most prolific authors. Mclnnes IB and Smolen JS were the most frequently cited authors. The journals with the most articles are Frontiers in Immunology, Arthritis Research & Therapy, and Arthritis & Rheumatology. Current research hotspots include pathogenic factors and targeted biological therapy, immune mechanisms, inflammatory mechanisms, and bone destruction mechanisms. The current research frontiers in this field are gut microbiota, identification, fibroblast-like synoviocytes, biologic therapy, mesenchymal stem cells, and risk. This work provides new insights into the scientific research and clinical application of T cells to develop therapeutic targets for RA.
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Affiliation(s)
- Yanfang Gao
- Basic Laboratory of Integrated Traditional Chinese and Western Medicine, Shanxi University of Chinese Medicine, Jinzhong, China
| | - Yang Liu
- Basic Laboratory of Integrated Traditional Chinese and Western Medicine, Shanxi University of Chinese Medicine, Jinzhong, China
- College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong, China
| | - Huiqin Hao
- Basic Laboratory of Integrated Traditional Chinese and Western Medicine, Shanxi University of Chinese Medicine, Jinzhong, China
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Schoenfeld AJ, Holly KE. Measuring Academic Productivity in Orthopedic and Spine Surgery. Spine (Phila Pa 1976) 2025; 50:793-795. [PMID: 40181668 DOI: 10.1097/brs.0000000000005350] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 03/31/2025] [Accepted: 04/01/2025] [Indexed: 04/05/2025]
Affiliation(s)
- Andrew J Schoenfeld
- Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
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Liu Y, Lu B, Yang X, Cui J, Yang T, Zhang H, Zhao Z, Lyu D, Li Y, Yao Y, Huang R, Pan X. Disclosing the development and focus of sequencing and omics studies in kidney neoplasm research. Discov Oncol 2025; 16:928. [PMID: 40418308 DOI: 10.1007/s12672-025-02750-6] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/20/2025] [Accepted: 05/19/2025] [Indexed: 05/27/2025] Open
Abstract
BACKGROUND Kidney cancer is a worldwide prevalent urological malignancy and the leading cause of death. Sequencing and omics studies play a crucial role in unraveling its molecular mechanisms and diagnostic, prognostic, and therapeutic relevance. This study aims to offer a comprehensive review of the evolving trends and hotspots of sequencing and omics studies in kidney neoplasms. METHODS We conducted the retrieval of scientific publications on sequencing and omics studies in kidney neoplasms from the Web of Science Core Collection (WoSCC) on July 3, 2023. The R-based bibliometrix package, VOSviewer, and CiteSpace were utilized to conduct the holistic bibliometric analysis to obtain objective and data-driven results. A comprehensive consultation of papers was then proceeded for an in-depth review. RESULTS Our investigation yielded a dataset containing 1260 records from 509 sources, with 43,404 references, from 1960 to 2023. Publication and citation frequencies have been consistently growing. In country analysis, China and the USA led the research, displaying substantial collaboration. Notable contributors like TEH BT, SAUTER G, and FUTREAL PA shaped this research landscape. Key journals such as PLoS One, Cancer Research, and New England Journal of Medicine actively participated in and significantly influenced this field. Distinguished publications and references were also revealed, along with their historical citation and co-citation relationships. A panel of keywords, including RCC, biomarker, and multi-omics data were identified and clustered. CONCLUSION We obtained a profound understanding of the developing trends and hotspots of research investigating sequencing and omics studies in kidney neoplasms. Specifically, we have highlighted three hotspots: "explore molecular mechanisms of RCC pathogenesis, progression, and metastasis", "identify molecular biomarkers of RCC for diagnosis, prognosis, and therapeutics", "investigate tumor heterogeneity and tailor personalized therapeutic strategies for RCC". Hopefully, our study will serve as a valuable reference for scientific researchers and clinical practitioners.
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Affiliation(s)
- Yifan Liu
- Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665 Kongjiang Road, Shanghai, 200092, China
| | - Bingnan Lu
- Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665 Kongjiang Road, Shanghai, 200092, China
| | - Xinyue Yang
- Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665 Kongjiang Road, Shanghai, 200092, China
| | - Jinming Cui
- Ulink College of Shanghai, Shanghai, 201615, China
| | - Tianyue Yang
- Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665 Kongjiang Road, Shanghai, 200092, China
| | - Haoyu Zhang
- Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665 Kongjiang Road, Shanghai, 200092, China
| | - Zihui Zhao
- Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665 Kongjiang Road, Shanghai, 200092, China
| | - Donghao Lyu
- Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665 Kongjiang Road, Shanghai, 200092, China
| | - Yuanan Li
- Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665 Kongjiang Road, Shanghai, 200092, China
| | - Yuntao Yao
- Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665 Kongjiang Road, Shanghai, 200092, China.
| | - Runzhi Huang
- Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, No. 168 Changhai Road, Shanghai, 200433, China.
| | - Xiuwu Pan
- Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 1665 Kongjiang Road, Shanghai, 200092, China.
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Xu J, Zou H, Shu C, Liu Y, Yin Y, Ni B. Research progress and hotspots of the impact of Mediterranean diet on aging from 2004 to 2023: A bibliometric analysis. Geriatr Nurs 2025; 64:103375. [PMID: 40408818 DOI: 10.1016/j.gerinurse.2025.05.014] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/21/2024] [Revised: 03/26/2025] [Accepted: 05/05/2025] [Indexed: 05/25/2025]
Abstract
OBJECTIVE This study aims to identify research hotspots and trends by conducting a bibliometric report regarding the impact of MD on aging. METHODS Publications on MD and aging were extracted from the Web of Science Core Collection. R software, VOSviewer and CiteSpace were employed to detect research hotspots and frontiers. RESULTS The number of annual articles has grown rapidly. The core research content in this field are the mechanism of the antiaging action of MD (inflammation, oxidative stress and gut microbiome) and age-related diseases (particularly cardiovascular diseases, Alzheimer's disease and metabolic syndrome). The interplay between MD and the gut microbiome or physical activity impacting healthy aging has been the recent hotspot and research frontier. CONCLUSION This study quantitatively and objectively described the research status and research focus of the impact of MD on aging, which provides reference for future research in this field.
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Affiliation(s)
- Jian Xu
- Department of Neurosurgery, The Affiliated Hospital of Qingdao University, Qingdao 266071, PR China
| | - Hao Zou
- Department of Hepatobilary and Pancreatic Surgery, The Affiliated Hospital of Qingdao University, Qingdao 266003, PR China
| | - Chuanliang Shu
- Department of Stomatology, Qingdao Traditional Chinese Medicine Hospital, Qingdao Hiser Hospital Affiliated to Qingdao University, Qingdao 266033, PR China
| | - Yanying Liu
- Department of Basic Medical, Qingdao Huanghai University, Qingdao 266427, PR China
| | - Yanlei Yin
- Department of Pharmacy, The Affiliated Hospital of Qingdao University, Qingdao 266003, PR China
| | - Beibei Ni
- Department of Pharmacy, The Affiliated Hospital of Qingdao University, Qingdao 266003, PR China.
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Abdelwahab SI, Farasani A, Moshi JM, Alshahrani S, Hassan W. Authorship analysis of publications in Naunyn-Schmiedeberg's Archives of Pharmacology (1969-2024). NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY 2025:10.1007/s00210-025-04253-1. [PMID: 40387930 DOI: 10.1007/s00210-025-04253-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 04/26/2025] [Accepted: 05/01/2025] [Indexed: 05/20/2025]
Abstract
Naunyn-Schmiedeberg's Archives of Pharmacology (NSAP) is the world's oldest journal in the field of pharmacology. Approximately fourteen bibliometric studies published by NSAP have examined its scholarly trajectory and role in pharmacology. However, no study has yet thoroughly analyzed author contributions throughout the journal's recent history. This study addresses the gap by analyzing all publications in NSAP from 1969-onward using data retrieved from the Scopus database. The dataset included bibliographic information such as titles, author names, affiliations, years of publication, and document types. During this period, NSAP published 13,422 documents-comprising 12,687 original articles and 735 reviews-with an annual publication growth rate of 2.74% and an average document age of 31.2 years. These publications received 252,490 citations, yielding an average of 18.81 citations per document. The top three most productive authors (based on number of publications) were Starke, K. (143 publications), Göthert, M. (106), and Seifert, R. (101). This ranking was consistent across three independent tools-VOSviewer, R Studio, and Scopus-reinforcing the accuracy of manual verification. A total of 14 authors were identified with at least 50 publications each. For this select group, detailed performance indicators were calculated. These indicators allowed for a multi-dimensional evaluation of author performance beyond simple publication counts. Precisely, we provided number of publications, total citations, citations per publication, h-index, g-index, m-index, HG composite index, Q2 index, and year of first publication for the 50 authors. In fact, the publication data for 23,476 authors are presented in supplementary Table 1 along with the stated indicators. This study highlights the extent of author involvement with NSAP and emphasizes the importance of using various tools and measures to gain a fuller understanding of academic productivity.
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Affiliation(s)
| | - Abdullah Farasani
- Department of Medical Laboratory Technology, Faculty of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia
| | - Jobran M Moshi
- Department of Medical Laboratory Technology, Faculty of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia
| | - Saeed Alshahrani
- Department of Pharmacology and Toxicology, College of Pharmacy, Jazan, Saudi Arabia
| | - Waseem Hassan
- Institute of Chemical Sciences, University of Peshawar, Peshawar, 25120, Khyber Pakhtunkhwa, Pakistan.
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Cai S, Yang W, Xing H, Yang J, Luo H, Ye X. Bibliometric analysis of current trends and emerging patterns in the application of nanomaterials for non-small cell lung cancer. Discov Oncol 2025; 16:802. [PMID: 40382731 PMCID: PMC12086128 DOI: 10.1007/s12672-025-02602-3] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/12/2025] [Accepted: 05/06/2025] [Indexed: 05/20/2025] Open
Abstract
BACKGROUND Lung cancer is one of the most prevalent tumor diagnoses and a leading cause of cancer-related mortality worldwide. Among its two primary subtypes, non-small cell lung cancer (NSCLC) accounts for approximately 80-85% of all lung cancer cases. Over the past decade, a significant number of publications have explored the application of nanomaterials in NSCLC. This study aimed to comprehensively evaluate the current state and evolving trends in research focused on utilizing nanomaterials as potent diagnostic and therapeutic tools for NSCLC. METHODS To identify all pertinent publications, we used the Web of Science Core Collection (WoSCC) database. Based on stringent inclusion and exclusion criteria, relevant publications were carefully selected. For the bibliometric and visual analyses, we employed VOSviewer (version 1.6.20), CiteSpace (version 6.1.6), and R-bibliometrix (version 4.3.2). RESULTS Our analysis encompassed 1880 studies that fulfilled the inclusion criteria. We observed a steady increase in annual publications from 2014 to June 22, 2024. China, the USA, and India have emerged as leading nations in this field. Notably, the Chinese Academy of Sciences and Wang J stood out as the most influential institutions and authors, respectively. Most publications are featured in The International Journal of Nanomedicine. The keywords used in these publications were closely tied to non-small cell lung cancer and nanomaterials. In the past three years, "green synthesis" exhibited the highest burst strength, while "immune response" and "nanocrystal" represented emerging areas of intense research interest. CONCLUSION Through our exhaustive analysis, we synthesized the current research trends and emerging landscapes of nanomaterials in NSCLC. We characterized the publication patterns, pinpointed the most influential nations, institutions, authors, journals, and hot topics related to nanomaterial applications in NSCLC, and proposed potential avenues for future development.
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Affiliation(s)
- Shanshan Cai
- Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, 1 Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China
| | - Weichang Yang
- Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, 1 Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China
| | - Hongquan Xing
- Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, 1 Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China
| | - Jiale Yang
- Hepatobiliary and Pancreatic Surgery Division, Department of General Surgery, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330038, China
| | - Hongdan Luo
- Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, 1 Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China
| | - Xiaoqun Ye
- Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, 1 Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China.
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Abdelwahab SI, Taha MME, Farasani A, Abdullah SM, Moshi JM, Khamjan NA, Alshahrani AF, Khired ZA, Assiri A, Alshahrani S, Elhilu AH, Hassan W. Teaching Spirituality in Nursing: Additional Evidence for Developing a Bibliometric Analysis. JOURNAL OF RELIGION AND HEALTH 2025:10.1007/s10943-025-02339-x. [PMID: 40372669 DOI: 10.1007/s10943-025-02339-x] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Accepted: 04/22/2025] [Indexed: 05/16/2025]
Abstract
Building upon previous bibliometric studies, this analysis expands the dataset and refines analytical methods to offer deeper insights into spirituality in nursing education. Using bibliometric techniques with Scopus, VOSviewer, and R Studio, 1227 papers were analyzed to identify key author contributions, leading institutions, and international collaborations. A comprehensive co-word analysis of the top 100 most cited papers revealed evolving research dynamics, mapping at least 50 key terms through uni-gram, bi-gram, and tri-gram approaches. Based on keyword analysis and their frequency of appearance, a generalized theme emerged around the significance of spiritual care in healthcare. The findings emphasized spiritual care's significance, particularly in palliative and end-of-life care, with growing integration into nursing education. Research explored its impact on clinical practice, patient well-being, and nursing perceptions, as well as how academic training prepares students for spiritual care. Various studies examined its effects on patient outcomes, coping strategies, and assessment tools. Beyond spirituality, broader healthcare topics, including mental health and pediatric palliative care, were addressed. Challenges in nursing education and innovative teaching strategies were also explored. This study advances the bibliometric understanding of spirituality in nursing education by uncovering thematic shifts, strengthening research methodologies, and broadening the scope of analysis in spiritual and holistic care education.
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Affiliation(s)
| | | | - Abdullah Farasani
- Health Research Center, Jazan University, Jazan, Kingdom of Saudi Arabia
- Department of Medical Laboratory Technology, Faculty of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia
| | - Saleh M Abdullah
- Department of Medical Laboratory Technology, Faculty of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia
| | - Jobran M Moshi
- Health Research Center, Jazan University, Jazan, Kingdom of Saudi Arabia
- Department of Medical Laboratory Technology, Faculty of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia
| | - Nizar A Khamjan
- Department of Medical Laboratory Technology, Faculty of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia
| | - Abrar Fahad Alshahrani
- Department of Clinical Nutrition, Faculty of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia
| | - Zenat A Khired
- Department of Surgery, Faculty of Medicine, Jazan University, Jazan, Saudi Arabia
| | - Ahmad Assiri
- Department of Dermatology, Faculty of Medicine, Jazan University, Jazan, Saudi Arabia
| | - Saeed Alshahrani
- Department of Pharmacology and Toxicology, College of Pharmacy, Jazan, Saudi Arabia
| | | | - Waseem Hassan
- Institute of Chemical Sciences, University of Peshawar, Peshawar, 25120, Khyber Pakhtunkhwa, Pakistan.
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Ríos Riquelme M, Denche-Zamorano Á, Salas-Gómez D, Castillo-Paredes A, Ferrari G, Marín-Guajardo C, Loro-Ferrer JF. Trends and Scientific Production on Isometric Training: A Bibliometric Analysis. Sports (Basel) 2025; 13:145. [PMID: 40423281 DOI: 10.3390/sports13050145] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/25/2025] [Revised: 04/17/2025] [Accepted: 04/28/2025] [Indexed: 05/28/2025] Open
Abstract
Isometric training is a method focused on muscle strengthening without joint movement and has gained attention in recent years due to its applicability in rehabilitation and sports medicine. However, no comprehensive bibliometric analysis focused exclusively on adult populations has been performed. This study aimed to analyze the scientific production related to isometric training in adults; identify prominent authors, journals, and thematic trends; and evaluate the evolution of interest in this field over time. A bibliometric review was performed using the Web of Science Core Collection (SCI-E, SSCI, and ESCI). A specific search strategy was applied to identify articles and reviews focused on isometric training in adult populations. A total of 238 records met the inclusion criteria. Data were analyzed using Excel 2016 and VOSviewer software1.6.20. Bibliometric indicators such as Price's Law, Bradford's Law, Lotka's Law, h-index, and co-occurrence and co-authorship network analysis were applied. The results showed a steady increase in publications in the last decade, highlighting the categories of Sports Science, Physiology, and Cardiovascular. The Journal of Applied Physiology was the most frequent source, and Springer Nature was the most prolific publisher. The h-index identified 21 highly cited papers, and Lotka's Law confirmed the existence of a small group of prolific authors. VOSviewer analysis revealed clear thematic clusters, mainly around blood pressure regulation, rehabilitation, and aging. International collaboration was evident, with the United States, Canada, and the United Kingdom leading the co-authorship networks. Scientific interest in isometric training for adult populations is growing, particularly in relation to cardiovascular health and rehabilitation. Despite this, gaps remain in terms of methodological consistency and standardized protocols. Addressing these issues could improve the applicability and scientific impact of this training modality.
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Affiliation(s)
- Mario Ríos Riquelme
- Escuela de Doctorado de la ULPGC, Universidad de Las Palmas de Gran Canaria, 35001 Las Palmas de Gran Canaria, Spain
- Escuela de Ciencias de la Actividad Física, el Deporte y la Salud, Universidad de Santiago de Chile (USACH), Santiago 9170022, Chile
| | - Ángel Denche-Zamorano
- Promoting a Healthy Society Research Group (PHeSO), Faculty of Sport Sciences, University of Extremadura, 10003 Cáceres, Spain
| | - Diana Salas-Gómez
- Promoting a Healthy Society Research Group (PHeSO), Faculty of Sport Sciences, University of Extremadura, 10003 Cáceres, Spain
- Departamento de Desporto e Saúde, Escola de Saúde e Desenvolvimento Humano, Universidade de Évora, 7004-516 Évora, Portugal
| | - Antonio Castillo-Paredes
- Grupo AFySE, Investigación en Actividad Física y Salud Escolar, Escuela de Pedagogía en Educación Física, Facultad de Educación, Universidad de Las Américas, Santiago 8370040, Chile
| | - Gerson Ferrari
- Escuela de Ciencias de la Actividad Física, el Deporte y la Salud, Universidad de Santiago de Chile (USACH), Santiago 9170022, Chile
- Faculty of Health Sciences, Universidad Autónoma de Chile, Providencia 7500912, Chile
| | - Cecilia Marín-Guajardo
- Escuela de Ciencias de la Actividad Física, el Deporte y la Salud, Universidad de Santiago de Chile (USACH), Santiago 9170022, Chile
| | - Juan Francisco Loro-Ferrer
- Departamento Ciencias Clínicas, Facultad de Ciencias de la Salud, Universidad de Las Palmas de Gran Canaria, 35016 Las Palmas de Gran Canaria, Spain
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Kasper B, Walker CM, Henry TS, Raptis C, Little BP. Academic influence of American College of Radiology Appropriateness Criteria: a citation analysis of thoracic and cardiac imaging guidelines. Clin Imaging 2025; 123:110505. [PMID: 40367562 DOI: 10.1016/j.clinimag.2025.110505] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/08/2025] [Revised: 04/23/2025] [Accepted: 05/08/2025] [Indexed: 05/16/2025]
Abstract
PURPOSE To evaluate the academic impact of the American College of Radiology thoracic and cardiac Appropriateness Criteria (ACR-AC) guideline publications through citation analysis. METHODS The Scopus database was used to collect publication year, version number, and number and identity of citing publications for thoracic and cardiac imaging ACR-AC guideline publications. For each citing article, the journal name and impact factor, publication year, countries of all authors, and language(s) of publication were collected. An article h-index was computed for each ACR-AC guideline. RESULTS 31 thoracic and cardiac ACR-AC guideline publications received 758 citations from 379 journals, with authors representing 62 countries. The median citation count was 15 (range = 1-97) and the median article h-index was 5 (range = 1-19). The most frequent country of authorship of articles citing an ACR-AC guideline publication was the United States, but 66.7 % of authors were from other countries. The median impact factor for the citing journals was 3.0 (range = 0.0-521.6). A majority of the total citations were from "Non-Radiology Journals" (n = 422/758 [55.7 %]) which comprised a majority of all journals represented (n = 295/379 [77.8 %]). CONCLUSIONS Citation characteristics of ACR-AC guideline publications suggest broad multidisciplinary and global academic influence.
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Affiliation(s)
- Bradley Kasper
- Edward Via College of Osteopathic Medicine - Virginia Campus, Department of Medical Education, United States of America
| | - Christopher M Walker
- Glen and Karen Cox Endowed Professor of Radiology, Vice Chair of Faculty Development, Department of Radiology, University of Kansas Health System, United States of America
| | - Travis S Henry
- Department of Radiology, Duke University Health, United States of America.
| | - Constantine Raptis
- Mallinckrodt Institute of Radiology, St. Louis, MO, United States of America.
| | - Brent P Little
- Division of Cardiothoracic Imaging, Mayo Clinic Florida, 4500 San Pablo Road, Jacksonville, FL 32224, United States of America.
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Li S, Yang Z, Lv M, Zong L, Xie Y, Cai Z, Zhang Y, Wang Z, Liu Z, Sang L. Research trends on lactate in cancer: a bibliometric analysis and comprehensive review (2015-2024). Front Immunol 2025; 16:1587867. [PMID: 40416986 PMCID: PMC12098457 DOI: 10.3389/fimmu.2025.1587867] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/05/2025] [Accepted: 04/15/2025] [Indexed: 05/27/2025] Open
Abstract
Objective A bibliometric approach was employed to systematically analyze the trends and potential future developments in lactic acid-related cancer research over the past 10 years. Method We conducted a bibliometric analysis of literature on lactic acid in cancer research from 2015 to 2024, using data collected from the Web of Science database. A bibliometric analysis was conducted to identify general research directions and trends in current publications, as well as to determine the most prolific and influential authors, institutions, countries, and keywords in lactate and cancer research. The data were collected and analyzed using VOSviewer (Leiden University, Leiden, Netherlands), Microsoft Excel (Microsoft, Redmond, Washington, USA), CiteSpace, and Biblioshiny, with a focus on analysis and visualization. Results A total of 5,999 publications were analyzed, focusing on various aspects of the relevant literature, including year of publication, country, institution, author, journal, category, keywords, and research frontiers. The analysis of these publications reveals a general upward trend in publication volume from 2015 to 2024, with China and University of California System emerging as the most prolific country and institution, respectively. SCIENTIFIC REPORTS is the most frequently published journal, while Oncotarget is the most cited journal in the field. Zhang Y. was the most prolific author, publishing 100 documents over 10 years, with the highest citation count and an H-index of 28.Keyword analysis revealed five key themes in lactate-cancer research (2013-2023): Metabolic-epigenetic crosstalk, Tumor immunosuppressive microenvironment, Innovative therapies/drug delivery, Lactate-mediated signaling, Metabolic-targeted treatment strategies. Current research emphasizes the application of lactic acid metabolism in metabolic intervention, immune microenvironment regulation, combination of new therapeutic techniques and applications in specific cancer types. Conclusion Research on lactic acid in cancer is growing rapidly, with China at the forefront of this field. Research into lactic acid's role in immune cell regulation, metabolism, and signaling pathways, combined with multi-modal imaging, big data analytics, and innovative drug delivery, is set to become a key trend in future studies, which promises new directions for identifying therapeutic targets, biomarkers, and developing advanced treatments.
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Affiliation(s)
- Sinong Li
- Department of Ultrasound, The First Hospital of China Medical University, Shenyang, China
| | - Ziyi Yang
- Department of Ultrasound, The First Hospital of China Medical University, Shenyang, China
| | - Mutian Lv
- Department of Nuclear Medicine, The First Hospital of China Medical University, Shenyang, China
| | - Lin Zong
- Department of Neurosurgery, The First Hospital of China Medical University, Shenyang, China
| | - Yihan Xie
- Department of Ultrasound, The First Hospital of China Medical University, Shenyang, China
| | - Zoujuan Cai
- Department of Ultrasound, The First Hospital of China Medical University, Shenyang, China
| | - Ying Zhang
- Department of Ultrasound, The First Hospital of China Medical University, Shenyang, China
| | - Zhongqing Wang
- Department of Information Center, The First Hospital of China Medical University, Shenyang, China
| | - Zhe Liu
- Department of Pancreatic-Biliary Surgery, The First Hospital of China Medical University, Shenyang, China
| | - Liang Sang
- Department of Ultrasound, The First Hospital of China Medical University, Shenyang, China
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Lozano-Sanroma J, Barros A, Queiruga-Piñeiro J, Alcalde I, Alvarado-Villacorta R, Fernández-Vega Cueto-Felgueroso L, Merayo-Lloves J. Corneal esthesiometry between 2000 and 2024: A bibliometric and knowledge mapping analysis. Medicine (Baltimore) 2025; 104:e42383. [PMID: 40355200 PMCID: PMC12073859 DOI: 10.1097/md.0000000000042383] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/21/2024] [Accepted: 04/21/2025] [Indexed: 05/14/2025] Open
Abstract
BACKGROUND Corneal esthesiometry plays a key role in assessing the integrity of the ocular surface. Its importance lies in the fact that several eye and systemic conditions can alter the corneal sensitivity. This is evidenced by the emergence of new devices to measure this parameter in recent years. METHODS Publications found in Web of Science and Scopus databases from 2000 to 2024 were analyzed. Microsoft Excel, Rayyan, and VOSviewer software were used. RESULTS A total of 556 articles were included in the study. Andrew JM Boulton had the greatest impact, with the highest h-index. The Centre for Contact Lens Research, School of Optometry, University of Waterloo (Canada), was the most prolific institution, with 25 articles published. The United States led the ranking of countries, with 81 publications. Six keyword clusters were identified, encompassing neurophysiology, dry eye, ocular pathology, diabetic neuropathy, structural nerve assessment, and refractive surgery. CONCLUSION This study reports on who, why, how many, and where corneal esthesiometry has been studied, through a bibliometric analysis. The studies centered on sensory physiology, ocular surface disease, and dry eye disease. These emerging trends highlight new clinical, diagnostic, and research perspectives, which may guide future investigations and contribute to more precise strategies for the treatment of ocular surface conditions.
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Affiliation(s)
- Javier Lozano-Sanroma
- Optometry Department, University Institute Fernández-Vega, Ophthalmological Research Foundation, Oviedo, Spain
| | - Alberto Barros
- Optometry Department, University Institute Fernández-Vega, Ophthalmological Research Foundation, Oviedo, Spain
| | - Juan Queiruga-Piñeiro
- Optometry Department, University Institute Fernández-Vega, Ophthalmological Research Foundation, Oviedo, Spain
| | - Ignacio Alcalde
- Ocular Surface and Nerve Regeneration Research, University Institute Fernández-Vega, Ophthalmological Research Foundation, Oviedo, Spain
- Institute for Health Research of the Principality of Asturias (ISPA), University of Oviedo, Oviedo, Spain
| | - Rosa Alvarado-Villacorta
- Research Department, University Institute Fernández-Vega, Ophthalmological Research Foundation, Oviedo, Spain
| | - Luis Fernández-Vega Cueto-Felgueroso
- Institute for Health Research of the Principality of Asturias (ISPA), University of Oviedo, Oviedo, Spain
- Cornea and Lens Unit, University Institute Fernández-Vega, Ophthalmological Research Foundation, Oviedo, Spain
| | - Jesús Merayo-Lloves
- Institute for Health Research of the Principality of Asturias (ISPA), University of Oviedo, Oviedo, Spain
- Director of Research, University Institute Fernández-Vega, Ophthalmological Research Foundation, Oviedo, Spain
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Shi Y, Wang J, Zhang Y, Wu K, Zhu Y, Yan K, Ouyang Q. Effectiveness of herbal medicine for liver cancer treatment as revealed by a bibliometric and visualization analysis. Front Oncol 2025; 15:1527091. [PMID: 40406241 PMCID: PMC12094935 DOI: 10.3389/fonc.2025.1527091] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/12/2024] [Accepted: 04/14/2025] [Indexed: 05/26/2025] Open
Abstract
Background Liver cancer is highly prevalent worldwide. However, current medical treatments remain insufficient. Although herbal medicine has a long history and extensive expertise in treating liver cancer, the literature in this field has not been thoroughly explored. This study aims to assess and analyze the distribution patterns and key research areas of publications concerning herbal medicine for liver cancer. Methods Literature on herbal medicine and liver cancer published between January 1, 2008, and September 28, 2024, was collected for this research. Excel, CiteSpace 6.4.R1, VOSviewer 1.6.20, Scimago Graphica, and Bibliometrix 4.1 were used for data analysis. Result The study examines 634 academic articles on herbal medicine for liver cancer, with the majority contributed by Chinese researchers, particularly from Shanghai University of Traditional Chinese Medicine. Wang Ning is the most productive author, possessing the highest h-index. The JOURNAL OF ETHNOPHARMACOLOGY has the most publications and the highest h-index. Journals publishing on herbal medicine and liver cancer are primarily in the fields of molecular biology and immunology, whereas the cited journals are mainly in the fields of environment, toxicology, and nutrition. Keyword clustering analysis indicates that "NF kappa B" and apoptosis have long been the main research topics in this field. Analysis of emergent words suggests that "network pharmacology", antioxidants, "adjuvant therapy", and "molecular docking" may become significant research topics in the near future. Conclusion This analysis provides a comprehensive overview of the current status, primary focuses, and emerging trends in research related to herbal medicine and liver cancer.
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Affiliation(s)
| | | | | | | | | | | | - Qin Ouyang
- Wenzhou TCM Hospital of Zhejiang Chinese Medical University, Wenzhou, China
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14
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Benn L, Montesinos GFDR, Botros M, Haddas R, Mesfin A. Academic and Demographic Characteristics of Spine Societies Presidents. Spine J 2025:S1529-9430(25)00247-5. [PMID: 40345398 DOI: 10.1016/j.spinee.2025.05.019] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/17/2024] [Revised: 04/10/2025] [Accepted: 05/01/2025] [Indexed: 05/11/2025]
Abstract
BACKGROUND CONTEXT There is limited information on spine society presidents' training backgrounds, academic productivity, and demographics. This is crucial because the individuals elected to this role are thought leaders and can impact the future trajectory of spine surgery. PURPOSE To characterize the training backgrounds, academic productivity, and demographics of presidents elected to serve in seven spine societies: Scoliosis Research Society (SRS), Cervical Spine Research Society (CSRS), North American Spine Society (NASS), Lumbar Spine Research Society (LSRS), International Society for the Study of the Lumbar Spine (ISSLS), American Association of Neurological Surgeons Spine (AANS Spine) and International Society for the Advancement of Spine Surgery (ISASS). STUDY DESIGN/SETTING Retrospective Cohort Study. OUTCOME MEASURES Training backgrounds, academic productivity, and demographics of spine societies presidents. METHODS This was a retrospective cohort study of seven spine society presidents (n=156) from 2000 to 2024. The information was retrieved via society websites for the SRS (n=24), CRSR (n=25), NASS (n=25), (n=25), ISSLS (n=25), AANS Spine (n=25), and ISASS (n=23). LSRS provided their list of presidents (n=9) upon request. Training backgrounds, current academic productivity, and demographic characteristics were obtained from online curriculum vitae, academic websites and Scopus. Data collection occurred from 06/19/2024 to 09/14/2024. RESULTS Most presidents (95.5%) were surgical providers (orthopaedic surgeons 106/156,67.9%; 43/156, 27.6% neurosurgeons). Only 7/156 (4.5%) were non-surgical providers. CSRS and SRS presidents had the highest cumulative publications and H-index, respectively. The academic rank at appointment was professor for 122/156 (78.2%) presidents. Of the 156 presidents, 12.9% were MD/PhDs. There were 150/156 males (96.2%), and 122/156 were white (78.2%). CONCLUSION Spine society presidents are mostly male orthopaedic surgeons with high scholarly output. Most had the academic rank of professor. As orthopaedic and neurosurgery training programs become more representative of the population, more leaders from diverse backgrounds may become future presidents of these societies.
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Affiliation(s)
- Lancelot Benn
- Medstar Orthopaedic Institute, Georgetown School of Medicine, Washington, DC, USA
| | | | - Mina Botros
- Department of Orthopaedics, University of Rochester Medical Center, Rochester, NY, USA
| | - Ram Haddas
- Department of Orthopaedics, University of Rochester Medical Center, Rochester, NY, USA
| | - Addisu Mesfin
- Medstar Orthopaedic Institute, Georgetown School of Medicine, Washington, DC, USA.
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Grillo R, Araújo Barretto MD, Brozoski MA, Melhem-Elias F, Zindel Deboni MC. Strategies to boost citations in maxillofacial surgery literature: A meta-data science analysis. J Craniomaxillofac Surg 2025:S1010-5182(25)00135-0. [PMID: 40324916 DOI: 10.1016/j.jcms.2025.04.007] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/17/2025] [Revised: 03/17/2025] [Accepted: 04/08/2025] [Indexed: 05/07/2025] Open
Abstract
In maxillofacial surgery literature, where innovation drives advancements in techniques and patient care, citations are particularly critical. The aim of this paper is to retrospectively review the correlation between various parameters and the number of citations. This study analyzed 47,572 articles across nine high-impact journals to identify evidence-based strategies for increasing citation counts. A separate bibliographic search on citation-boosting strategies included 109 articles, of which 24 met the inclusion criteria. Statistical analyses included Pearson's correlation, odds ratios, Chi-square tests, and linear regression, performed using RStudio. Key findings indicated that articles with four authors were cited significantly more often (OR = 2.31, 95 % CI: 1.89-2.74, p < 0.001). Titles with approximately 13 words optimized visibility (p = 0.007), and articles around six pages in length balanced depth and readability (p = 0.012). Regression analyses showed that colons in titles positively influenced citation rates (β = 1.42, p < 0.001), while hyphens had a weaker or negative impact in high-impact journals (β = -0.85, p = 0.039). English was the dominant language in maxillofacial surgery literature (99.36 %). Reviews were cited 2.5 times more often than original research articles (p < 0.001). This study highlights actionable strategies to boost citations in maxillofacial surgery literature, leveraging a meta-data science approach to provide evidence-based recommendations. However, it should be clear that statistical analyses do not imply causation, and these recommendations should not be considered a definitive guide to boosting citations.
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Affiliation(s)
- Ricardo Grillo
- Department of Oral and Maxillofacial Surgery, University of São Paulo School of Dentistry, São Paulo-SP, Brazil.
| | | | - Mariana Aparecida Brozoski
- Department of Oral and Maxillofacial Surgery, University of São Paulo School of Dentistry, São Paulo-SP, Brazil.
| | - Fernando Melhem-Elias
- Department of Oral and Maxillofacial Surgery, University of São Paulo School of Dentistry, São Paulo-SP, Brazil.
| | - Maria Cristina Zindel Deboni
- Department of Oral and Maxillofacial Surgery, University of São Paulo School of Dentistry, São Paulo-SP, Brazil.
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Biswas S, Chakrabarti BK, Ghosh A, Ghosh S, Józsa M, Néda Z. Does Excellence Correspond to Universal Inequality Level? ENTROPY (BASEL, SWITZERLAND) 2025; 27:495. [PMID: 40422450 DOI: 10.3390/e27050495] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 03/21/2025] [Revised: 04/19/2025] [Accepted: 04/30/2025] [Indexed: 05/28/2025]
Abstract
We study the inequality of citations received for different publications of various researchers and Nobel laureates in Physics, Chemistry, Medicine and Economics using Google Scholar data from 2012 to 2024. Citation distributions are found to be highly unequal, with even greater disparity among Nobel laureates. Measures of inequality, such as the Gini and Kolkata indices, emerge as useful indicators for distinguishing Nobel laureates from others. Such high inequality corresponds to growing critical fluctuations, suggesting that excellence aligns with an imminent (self-organized dynamical) critical point. Additionally, Nobel laureates exhibit systematically lower values of the Tsallis-Pareto parameter b and Shannon entropy, indicating more structured citation distributions. We also analyze the inequality in Olympic medal tallies across countries and find similar levels of disparity. Our results suggest that inequality measures can serve as proxies for competitiveness and excellence.
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Affiliation(s)
- Soumyajyoti Biswas
- Department of Physics, SRM University-AP, Amaravati 522240, India
- Department of Computer Science and Engineering, SRM University-AP, Amaravati 522240, India
| | - Bikas K Chakrabarti
- Saha Institute of Nuclear Physics, Kolkata 700064, India
- Economic Research Unit, Indian Statistical Institute, Kolkata 700108, India
| | - Asim Ghosh
- Department of Physics, Raghunathpur College, Raghunathpur, Purulia 723133, India
| | - Sourav Ghosh
- Department of Physics, SRM University-AP, Amaravati 522240, India
| | - Máté Józsa
- Deptartment of Physics, Babeş-Bolyai University, 400347 Cluj-Napoca, Romania
| | - Zoltán Néda
- Deptartment of Physics, Babeş-Bolyai University, 400347 Cluj-Napoca, Romania
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17
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Halperin SJ, Gilson A, Dhodapkar MM, Prenner M, Tuason D, Grauer JN. Relative Citation Ratio Among Pediatric Orthopaedic Surgeons: Examining the Factors Associated With Higher Scores. J Am Acad Orthop Surg 2025; 33:481-487. [PMID: 39693538 DOI: 10.5435/jaaos-d-24-00756] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 07/09/2024] [Accepted: 11/09/2024] [Indexed: 12/20/2024] Open
Abstract
INTRODUCTION Academic scholarship is often valued by clinicians, peers, and intuitions. Quantifying the effect of research publications is challenging. Various metrics have been used to assess this. This study aimed to examine the relatively new research metric, relative citation ratio (RCR), introduced by the National Institutes of Health, for pediatric orthopaedic surgeons to establish the benchmarking of research effect within the field and understand the distribution and basis for the use of this metric among pediatric orthopaedic surgeons. METHODS The RCR indices were assessed for members of the Pediatric Orthopaedic Society of North America using the iCite online web service. The mean RCR (mRCR, the yearly average RCR) and weighted RCR (wRCR, the cumulative RCR score) were assessed for each member. This information was used to perform univariate and two multivariate ordinary least squares regressions for the two metrics. Independent variables were physician sex, years since receiving national provider identifier, MD versus DO degree, whether the physician had a PhD, and geographic region of practice (Northeast, Southeast, Midwest, West, and Southwest). RESULTS A total of 770 pediatric orthopaedic physicians were identified. The median [interquartile range] wRCR was 15.6 [4.9 to 54.2], and median mRCR was 1.4 [1.0 to 1.9]. Multivariable squares regression for wRCR showed an independently increased wRCR associated with male sex (39.11), PhD (23.32), years since receiving national provider identifier (4.51), and northeast region (48.44). However, these trends were not notable for mRCR where only southeast region was notable. CONCLUSION Although each has its caveats, both mRCR and wRCR have a place in evaluating an author's publication history and other research metrics. Furthermore, it is important to know the overall research metrics within a field to allow for inter- and intraspecialty comparisons. Understanding RCR is helpful because it allows for new comparisons within and across fields and career lengths.
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Affiliation(s)
- Scott J Halperin
- From the Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT
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Hassan W, Paas F. Bibliometric comparison of Nobel Prize laureates: a few suggestions. NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY 2025; 398:6123-6128. [PMID: 39625486 DOI: 10.1007/s00210-024-03648-w] [Citation(s) in RCA: 1] [Impact Index Per Article: 1.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Subscribe] [Scholar Register] [Received: 11/08/2024] [Accepted: 11/18/2024] [Indexed: 04/11/2025]
Abstract
This study offers insights into a paper by the esteemed editor-in-chief, who conducted a bibliometric comparison of Nobel laureates in physiology, medicine, and chemistry to examine the substantial influence these scientists have had on their respective fields (Naunyn-Schmiedeberg's Arch Pharmacol, 397, 2024, 7169-7185). Analyzing metrics such as laureates' nationalities, ages at productivity peaks, H-index, and age-adjusted H-index, the research highlights distinct career patterns among these distinguished scientists. The present study addresses the limitations of traditional metrics, like the H-index, which may undervalue early-career contributions or multidisciplinary impacts due to its focus on cumulative citations. Alternative indicators such as the H-upper, H-center, and H-tail indices are proposed to capture more balanced aspects of scholarly influence, highlighting top-cited, moderately cited, and broadly influential work, respectively. This study also suggests the value of incorporating composite indices such as the HG-composite and Q2 indices in relevant future studies. A list of other indicators is also provided, which may be employed in similar studies. In the same vein, altmetrics, such as social media engagement, download counts, and mentions in digital and traditional media, further complement these metrics by illustrating the broader, more immediate societal relevance of Nobel laureates' work. The present study proposes a multi-dimensional approach for evaluating research impact, integrating various metrics, and highlighting the need for cross-database comparisons to ensure accurate assessments.
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Affiliation(s)
- Waseem Hassan
- Institute of Chemical Sciences, University of Peshawar, Peshawar, 25120, Khyber Pakhtunkhwa, Pakistan.
| | - Fred Paas
- Department of Psychology, Education and Child Studies, Erasmus University Rotterdam, Rotterdam, the Netherlands
- School of Education, University of New South Wales, Sydney, Australia
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Levine D, McDonald S, Lum S, Jordon M. Commonly Used Statistical Methods in Occupational Therapy Research. Am J Occup Ther 2025; 79:7903345010. [PMID: 40238637 DOI: 10.5014/ajot.2025.050852] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 04/18/2025] Open
Abstract
IMPORTANCE Current barriers exist that affect occupational therapy students' and practitioners' ability to understand statistical methods and translate knowledge into their clinical work. OBJECTIVE To determine which statistical methods are most commonly used in the occupational therapy literature and, consequently, which methods are most critical to include in occupational therapy curricula to equip students to be better consumers of occupational therapy literature and implement evidence in practice. DESIGN A thorough analysis of 1,223 journal articles across 13 core occupational therapy journals. The most common statistical methods from the core journals were recorded. OUTCOMES AND MEASURES The frequencies and percentages of each statistical method that were reported were calculated, and the top 25 statistical methods were ranked. RESULTS The analysis revealed that the top statistical methods included descriptive statistics, t tests, confidence intervals, χ2, effect size, analysis of variance, parametric correlations, Cronbach's α, post hoc analysis and pairwise comparisons, and thematic analysis and coding. CONCLUSIONS AND RELEVANCE The study determined the top 25 statistical methods used in the core occupational therapy literature. Occupational therapy educational programs can use this study as guidance for the inclusion of statistical content in their respective programs. Plain-Language Summary: This study was conducted to determine which statistical methods are most commonly used in occupational therapy research. We reviewed 13 key occupational therapy journals and identified the 25 most frequently used methods. These results can help improve how statistics is taught in occupational therapy programs.
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Affiliation(s)
- David Levine
- David Levine, PT, PhD, DPT, MPH, FAPTA, is Professor and Walter M. Cline Chair of Excellence in Physical Therapy, Physical Therapy, University of Tennessee at Chattanooga;
| | - Susan McDonald
- Susan McDonald, EdD, OTR/L, is Associate Professor of Occupational Therapy (retired), Occupational Therapy, University of Tennessee at Chattanooga
| | - Sara Lum
- Sara Lum, OTD, OTR/L, is Assistant Professor of Occupational Therapy, Occupational Therapy, University of Tennessee at Chattanooga
| | - Max Jordon
- Max Jordon, PT, DPT, PhD, is Associate Professor of Physical Therapy, Physical Therapy, University of Tennessee at Chattanooga
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Wen B, Li H, Liu X, Shu Y, Shen D, Bu X, Peng D, Liu Y, Li L. Systematic bibliometric and visualized analysis of research hotspots and trends in obstructive sleep apnea neuroimaging. Behav Sleep Med 2025; 23:414-435. [PMID: 40116438 DOI: 10.1080/15402002.2025.2479795] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Indexed: 03/23/2025]
Abstract
BACKGROUND Obstructive sleep apnea (OSA) patients exhibit neurological symptoms, driving research in sleep medicine and clinical neurology. Neurologists and radiologists explore detection methods to identify unique neural features associated with OSA in the atypical nervous system. Neuroimaging research in OSA encompasses studying the structural, functional connectivity (FC), and neurometabolic aspects of the brain. Limited resources and OSA's heterogeneity pose challenges to effective neuroimaging research. This study aims to conduct a bibliometric analysis of OSA neuroimaging research to identify key trends and emerging themes. METHODS This research utilizes various techniques, including functional MRI, structural MRI, diffusion tensor imaging, magnetic resonance spectroscopy, and electroencephalography, among others. Publications from 1993 to 2023 were retrieved from Web of Science on neuroimaging. Analysis tools included Bibliometric.com, CiteSpace, VOSviewer, and R4.3.2. RESULTS A total of 714 papers were published in 47 countries, with 651 articles, 55 reviews, and 8 meeting abstracts. The USA led in publications, with the University of California System contributing most, primarily in "Sleep" journal. The study identified 2916 authors, with Macey PM having the highest publication count. Recent years highlighted burst keywords such as network, classification, sleep staging, FC, and brain activity. Analysis of keyword clusters revealed "electroencephalography" with the longest temporal duration. CONCLUSIONS Neuroimaging in OSA research has gained increased attention. Incorporating behavioral sleep medicine insights could enhance understanding of OSA's impact on brain function and behavior. This study aims to assist researchers in identifying potential collaborators, institutions, and key themes, providing a comprehensive perspective on OSA neuroimaging research and related sleep disorders.
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Affiliation(s)
- Bing Wen
- Department of Radiology, Yiyang Central Hospital, Yiyang, Hunan Province, China
| | - Haijun Li
- Jiangxi Provincial Key Laboratory for Precision Pathology and Intelligent Diagnosis, Department of Radiology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China
| | - Xiang Liu
- Jiangxi Provincial Key Laboratory for Precision Pathology and Intelligent Diagnosis, Department of Radiology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China
| | - Yongqiang Shu
- Jiangxi Provincial Key Laboratory for Precision Pathology and Intelligent Diagnosis, Department of Radiology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China
| | - Dan Shen
- Department of Radiology, Yiyang Central Hospital, Yiyang, Hunan Province, China
| | - Xinyi Bu
- Department of Radiology, Yiyang Central Hospital, Yiyang, Hunan Province, China
| | - Dechang Peng
- Jiangxi Provincial Key Laboratory for Precision Pathology and Intelligent Diagnosis, Department of Radiology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China
| | - Yuting Liu
- Department of Ophthalmology, Hunan Children's Hospital, Changsha, Hunan Province, China
| | - Lifeng Li
- Jiangxi Provincial Key Laboratory for Precision Pathology and Intelligent Diagnosis, Department of Radiology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China
- Department of Radiology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan Province, China
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Niitsuma T, Yoshida M, Tamori H, Nakawake Y. Prestige bias drives the viral spread of content reposted by influencers in online communities. Sci Rep 2025; 15:15282. [PMID: 40312546 PMCID: PMC12046028 DOI: 10.1038/s41598-025-98955-4] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/11/2024] [Accepted: 04/16/2025] [Indexed: 05/03/2025] Open
Abstract
Cultural evolution theory suggests that prestige bias-whereby individuals preferentially learn from prestigious figures-has played a key role in human ecological success. However, its impact within online environments remains unclear, particularly with respect to whether reposts by prestigious individuals amplify diffusion more effectively than reposts by noninfluential users. We analyzed over 55 million posts and 520 million reposts on Twitter (currently X) to examine whether users with high influence scores (hg indices) more effectively amplified the reach of others' content. Our findings indicate that posts shared by influencers are more likely to be further shared than those shared by non-influencers. This effect persisted over time, especially in viral posts. Moreover, a small group of highly influential users accounted for approximately half of the information flow within repost cascades. These findings demonstrate a prestige bias in information diffusion within the digital society, suggesting that cognitive biases shape content spread through reposting.
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Affiliation(s)
- Takuro Niitsuma
- Media R&D Center, The Asahi Shimbun Company, 5-3-2 Tsukiji, Chuo-ku, Tokyo, Japan.
| | - Mitsuo Yoshida
- Institute of Business Sciences, University of Tsukuba, 3-29-1 Otsuka, Bunkyo-ku, Tokyo, Japan
| | - Hideaki Tamori
- Media R&D Center, The Asahi Shimbun Company, 5-3-2 Tsukiji, Chuo-ku, Tokyo, Japan
| | - Yo Nakawake
- Graduate School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology, 1-1 Asahidai, Nomi, Ishikawa, 923-1211, Japan.
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Alhumaidan AA, Alam BF, Alsuwaiyan A, Aljoghaiman EA, Helmi M, Ali S. Scientific Research Trend on Guided Tissue Regeneration: A Bibliometric Analysis. Eur J Dent 2025; 19:409-419. [PMID: 39572191 PMCID: PMC12020599 DOI: 10.1055/s-0044-1791529] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 04/17/2025] Open
Abstract
OBJECTIVES Guided tissue regeneration (GTR) is a widely used technique in contemporary dentistry which helps achieve regeneration of periodontal tissues. This study aims to identify leading countries, authors, institutes, journals, scientific publications, and mostly used keyword regarding role of GTR in treatment for periodontal disease using the Scopus database. MATERIALS AND METHODS A well-curated search through Scopus database for significant literature related to GTR published between 1987 and 2023 was performed. Bibliographical data which comprised of abstracts, title, keywords, references, citations, and other relevant information were composed. The data was analyzed using MS Excel and VOSviewer. RESULTS Scientific literature on GTR was manually scrutinized, and 308 paper were analyzed using the Scopus database. The first paper on GTR was published in 1987. Journal of Periodontology was identified as the leading journal, while the United States and Italy were the top contributing countries. University of Sienna was the most productive organization. Roberto Pontoriero was identified as the highly cited author. A highly cited scientific paper was published by Pintippa Bunyaratavej in 2001. CONCLUSION The present bibliometric study gives useful information related to the total number of scientific articles published from 1987 to 2023. A rising trend of scientific publication was identified which continued followed by a notable decline after 2004. The analysis also recognized the United States and University of Sienna, from Italy as most active country and organizations, while the Journal of Periodontology as the leading journal. CLINICAL RELEVANCE This study may assist in continuing education and evidence-based practice for clinicians and new researchers by providing knowledge and aiding literature searches in the domain of GTR used in treatment for periodontal conditions.
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Affiliation(s)
- Abdulkareem Abdullah Alhumaidan
- Department of Preventive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
| | - Beenish Fatima Alam
- Department of Oral Biology, Bahria University Dental College, Karachi, Pakistan
| | - Asim Alsuwaiyan
- Periodontics Unit, Dental Department, King Fahd Military Medical Complex, Dhahran, Saudi Arabia
| | - Eman Ahmed Aljoghaiman
- Department of Preventive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
| | - Mohammad Helmi
- Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia
| | - Saqib Ali
- Department of Biomedical Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
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Zhang W, Song J, Xian S, Xie S, Liu Y, Yao Y, Tong X, Wu X, Li Y, Zhang H, Lu B, Zhou J, Zhou Y, Xu D, Huang R, Ji S. A bibliometric analysis of rheumatology: knowledge structure and research trends of RNA-Binding proteins in rheumatic diseases. Clin Rheumatol 2025:10.1007/s10067-025-07403-1. [PMID: 40307540 DOI: 10.1007/s10067-025-07403-1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/22/2024] [Revised: 03/05/2025] [Accepted: 03/11/2025] [Indexed: 05/02/2025]
Abstract
BACKGROUND Rheumatic disease is a kind of disease dominated by inflammatory lesions of connective tissue and abnormal immune function. It mostly belongs to autoimmune diseases or connective tissue diseases affecting multiple organs. Meanwhile, understanding the role of RNA-binding proteins (RBPs) in pathogenesis is rapidly developing. This study aims at summarizing the hotspots in rheumatology studies related to RBPs. METHODS Scientific papers on RBPs related to rheumatology between 1982 and 2022 were gathered from the Web of Science database. The data analysis and visualization were obtained using the Bibliometrix package. Bibliometrix package was used to analyze bibliometric indicators and visualize the trends and hotspots of the research. RESULTS A total of 964 articles met the requirement. From 1982 to 2022, the USA and Anhui Medical University were the most productive country and institution, respectively, in this field. Arthritis and Rheumatism, Annals of the Rheumatic Diseases and Arthritis & Rheumatology were the top three periodicals obtained by Bradford's law. Co-word analysis divided the keywords into three clusters, focusing on diagnosis and classification of Systemic Lupus Erythematosus, pathogenesis of osteoarthritis and pathogenesis of Rheumatoid Arthritis, respectively. Trend topic analysis revealed that pathogenesis and classification of rheumatic diseases might be the research trend. CONCLUSION Focusing on RBPs in rheumatic diseases, we illustrated the evolution of this field and predicted future research hotspots. The research trend topics have evolved towards clinical classification and pathogenesis at the molecular and genetic level. The pathogenic mechanism in rheumatic diseases will continue to be a hotspot in the future. Besides, the classification of Systemic Lupus Erythematosus patients may be another hotspot. Researchers are recommended to pay more attention to hotspots demonstrated in the future. Key Points • Bibliometrix package was used to analyze bibliometric indicators and visualize the trends and hotspots of the research. • Focusing on RBPs in rheumatic diseases, we illustrated the evolution of this field and predicted future research hotspots. • The research trend topics have evolved towards clinical classification and the pathogenesis at the molecular and genetic level. • The pathogenic mechanism in rheumatic diseases will continue to be a hotspot in the future.
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Affiliation(s)
- Wei Zhang
- Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China
- Research Unit of Key Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, 200433, China
| | - Jiaqi Song
- Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China
| | - Shuyuan Xian
- Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China
- Research Unit of Key Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, 200433, China
| | - Sujie Xie
- Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China
- Research Unit of Key Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, 200433, China
| | - Yifan Liu
- Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China
- BGI Research, BGI-Hangzhou, Hangzhou, 310012, China
| | - Yuntao Yao
- Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China
- BGI Research, BGI-Hangzhou, Hangzhou, 310012, China
| | - Xirui Tong
- Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China
- Research Unit of Key Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, 200433, China
| | - Xinru Wu
- Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China
| | - Yuanan Li
- Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China
| | - Haoyu Zhang
- Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China
| | - Bingnan Lu
- Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China
| | - Jiajie Zhou
- Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China
| | - Yibin Zhou
- Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China
| | - Dayuan Xu
- Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
- Research Unit of Key Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, 200433, China.
| | - Runzhi Huang
- Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
- Research Unit of Key Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, 200433, China.
| | - Shizhao Ji
- Department of Burn Surgery, The First Affiliated Hospital of Naval Medical University, Shanghai, 200433, China.
- Research Unit of Key Techniques for Treatment of Burns and Combined Burns and Trauma Injury, Chinese Academy of Medical Sciences, Shanghai, 200433, China.
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Xiu Y, Zhang Y, Su Y, Zhu C, Liu Z. A bibliometric analysis of strabismus (from 2004 to 2023). Front Med (Lausanne) 2025; 12:1488817. [PMID: 40357290 PMCID: PMC12066748 DOI: 10.3389/fmed.2025.1488817] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/30/2024] [Accepted: 04/07/2025] [Indexed: 05/15/2025] Open
Abstract
Over the past two decades, strabismus research has evolved significantly, driven by innovations in AI-assisted diagnostics, minimally invasive surgical techniques, and a heightened focus on psychosocial outcomes and systemic disease linkages. This bibliometric analysis of 4,515 articles from the Web of Science Core Collection (2004-2023) maps global research trends, identifying the United States of America (USA), China, and the United Kingdom (UK) as leading contributors. A keyword co-occurrence analysis highlights a shift toward innovative treatments, including non-surgical interventions, and highlights the growing interest in interdisciplinary approaches that integrate clinical practice with psychological and social dimensions of strabismus. In conclusion, this bibliometric review provides a comprehensive overview of current strabismus research and identifies key areas for further investigation, serving as a valuable resource for researchers and clinicians aiming to advance the field.
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Affiliation(s)
- Yanghui Xiu
- Affiliated Xiamen Eye Center and Eye Institute, School of Medicine, Xiamen University, Xiamen, Fujian, China
- Xiamen Clinical Research Center for Eye Diseases, Xiamen, Fujian, China
- Xiamen Key Laboratory of Ophthalmology, Xiamen, Fujian, China
- Fujian Key Laboratory of Corneal & Ocular Surface Diseases, Xiamen, Fujian, China
- Xiamen Key Laboratory of Corneal & Ocular Surface Diseases, Xiamen, Fujian, China
- Translational Medicine Institute of Xiamen Eye Center of Xiamen University, Xiamen, Fujian, China
- Longyan Eye Hospital, Xiamen Eye Center and Eye Institute of Xiamen University, Xiamen, China
| | - Yujie Zhang
- Affiliated Xiamen Eye Center and Eye Institute, School of Medicine, Xiamen University, Xiamen, Fujian, China
- Xiamen Clinical Research Center for Eye Diseases, Xiamen, Fujian, China
- Xiamen Key Laboratory of Ophthalmology, Xiamen, Fujian, China
- Fujian Key Laboratory of Corneal & Ocular Surface Diseases, Xiamen, Fujian, China
- Xiamen Key Laboratory of Corneal & Ocular Surface Diseases, Xiamen, Fujian, China
- Translational Medicine Institute of Xiamen Eye Center of Xiamen University, Xiamen, Fujian, China
| | - Yu Su
- Affiliated Xiamen Eye Center and Eye Institute, School of Medicine, Xiamen University, Xiamen, Fujian, China
| | - Chufan Zhu
- Affiliated Xiamen Eye Center and Eye Institute, School of Medicine, Xiamen University, Xiamen, Fujian, China
| | - Zhen Liu
- Affiliated Xiamen Eye Center and Eye Institute, School of Medicine, Xiamen University, Xiamen, Fujian, China
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Abdelwahab SI, Farasani A, Moshi JM, Alshahrani S, Hassan W. Analysis of bibliometric research featured in Naunyn-Schmiedeberg's Archives of Pharmacology. NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY 2025:10.1007/s00210-025-04190-z. [PMID: 40272518 DOI: 10.1007/s00210-025-04190-z] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 04/09/2025] [Accepted: 04/14/2025] [Indexed: 04/25/2025]
Abstract
This study examines twelve (12) bibliometric research published in Naunyn-Schmiedeberg's Archives of Pharmacology and offers suggestions to improve future bibliometric analyses. By reviewing twelve influential studies, the research focuses on identifying trends in methodologies, databases, and bibliometric indicators. The reviewed studies span diverse topics, from the pharmacological effects of emodin to cancer therapies and neurodegenerative diseases. Common techniques, such as keyword co-occurrence analysis, citation burst detection, and country and institutional collaboration networks, were applied to explore research dynamics and emerging trends. However, a key observation is the predominant reliance on the Web of Science Core Collection as the sole database. While this database is widely recognized, the study suggests incorporating multiple databases to reduce bias and provide a more comprehensive understanding of the research landscape. Additionally, it recommends the use of various author performance indicators, such as the H-index, G-index, and M-index, to better capture an author's scholarly impact. The review also emphasizes the value of co-word analysis and citation burst detection in identifying research hotspots and thematic shifts. However, it advocates for more detailed co-word analysis by separately considering titles, abstracts, and keywords, co-words dynamics, and multi-gram analysis. This multi-layered approach could enhance the understanding of evolving research topics. The feedback provided is intended as constructive suggestions aimed at refining methodologies and fostering innovation in bibliometric studies within the field of pharmacology. In the same vein, the immense work of all authors is sincerely appreciated.
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Affiliation(s)
| | - Abdullah Farasani
- Department of Medical Laboratory Technology, Faculty of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia
| | - Jobran M Moshi
- Department of Medical Laboratory Technology, Faculty of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia
| | - Saeed Alshahrani
- Department of Pharmacology and Toxicology, College of Pharmacy, Jazan, Saudi Arabia
| | - Waseem Hassan
- Institute of Chemical Sciences, University of Peshawar, Peshawar, 25120, Khyber Pakhtunkhwa, Pakistan.
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Costello AA, Cohen-Rosenblum AR, Borsinger TM, Novicoff WM, Browne JA. A Study of Arthroplasty Surgeons Who Opt Out of Medicare. J Arthroplasty 2025:S0883-5403(25)00375-4. [PMID: 40273958 DOI: 10.1016/j.arth.2025.04.039] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 12/28/2024] [Revised: 04/04/2025] [Accepted: 04/14/2025] [Indexed: 04/26/2025] Open
Abstract
BACKGROUND Physicians may choose to opt out of accepting reimbursements through the Medicare program. There is limited information on arthroplasty surgeons who elect to opt out of Medicare. METHODS The public Centers for Medicare & Medicaid Services Opt-Out Affidavits Dataset was used to identify individual orthopaedic surgeons performing hip and knee arthroplasty who had opted out of Medicare as of February 2024. Publicly available internet pages were used to investigate individual surgeon characteristics and evaluate trends among those surgeons who opted out of Medicare over time. RESULTS Of the 308 orthopaedic surgeons who did not accept Medicare, 85 performed hip and/or knee arthroplasty. Of these surgeons, 37% practiced in or near New York City, while 27% practiced in the Southwest United States. All practiced in urban areas. At the time of opt out, physicians had an average time in practice of 21.3 years and a median of 20 years (range, five to 46). Surgeons had an average H-index of 17.6 and a median of six (range, zero to 82). Approximately, half of the surgeons were fellowship-trained in arthroplasty. Of these, 39% completed their training at the same institution. Surgeons received a mean of $377,178 and a median of $2,520 (range, zero to $10,631,606) from industry payments in the most recent year. This includes 47 (56%) who received less than $5,000 and nine (11%) who received over $1,000,000. In addition, 53% accepted insurance plans other than Medicare, and 25% had ownership of outpatient surgery centers. Also, the annual incidence of arthroplasty surgeon opt outs was higher in 2023 than in any year previously. CONCLUSIONS Arthroplasty surgeons who opt out of Medicare have diverse demographic, academic, and financial characteristics. Features commonly shared were geographic location and fellowship institution, while other characteristics vary substantially.
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Affiliation(s)
- Alyssa A Costello
- Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia
| | | | - Tracy M Borsinger
- Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia
| | - Wendy M Novicoff
- Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia
| | - James A Browne
- Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia
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Liu H, Zhu J, Chen H, Lin X. Global research trends and basis of venous/lymphatic malformations during 2003-2023: a bibliometric study over two decades. Front Med (Lausanne) 2025; 12:1555168. [PMID: 40313542 PMCID: PMC12045100 DOI: 10.3389/fmed.2025.1555168] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/03/2025] [Accepted: 03/24/2025] [Indexed: 05/03/2025] Open
Abstract
Introduction Venous/lymphatic malformations (VM/LM) represent a group of vascular anomalies that share similarities in diagnosis, classification, management, and pathogenesis. Despite growing research interest, no comprehensive bibliometric analysis has been conducted to map the knowledge landscape and evolution of VM/LM studies. Methods We searched the Web of Science Core Collection database for VM/LM-related publications from January 2003 to December 2023. multiple analytical tools including VOSviewer, CiteSpace, and R package 'bibliometrix' were used to analyze publication trends, collaboration networks, and research hotspots. Results 4,747 publications with 57,893 references were enrolled and analyzed. The number of publications is growing generally and erupted in 2019. The USA, China, and Japan are the top 3 countries in publication. The main study centers are scattered in the USA, Europe, China, and Japan. Fishman SJ published most. Vikkula M was cited most. Journal of Pediatric Surgery published and was cited most. The knowledge basis of VM/LM contains a wide range of concepts including classification/differential diagnosis, genetic causes, Sirolimus treatment, localized intravascular coagulopathy, and percutaneous treatment. The topic trend mainly changed after 2019 to genetic study and targeted therapy. Discussion This is the first bibliometric analysis of VM/LM research demonstrating the field's rapid growth and shifting research hotspots. Four key future directions emerged: molecular-level diagnosis and classification, precision targeted therapy, advanced sclerotherapy techniques, and artificial intelligence applications. International collaboration between countries and centers needs to be strengthen. These findings provide an objective foundation for future VM/LM investigations.
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Affiliation(s)
- Hongyuan Liu
- Department of Plastic and Reconstructive Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
| | - Jun Zhu
- Department of Urology, Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
| | - Hui Chen
- Department of Plastic and Reconstructive Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
| | - Xiaoxi Lin
- Department of Plastic and Reconstructive Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
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Zhou H, Liu S, Xiao Z, Yin S, Fan B, Sun G. Obesity and psychology: a bibliometric analysis of half a century. Front Nutr 2025; 12:1539587. [PMID: 40308634 PMCID: PMC12040703 DOI: 10.3389/fnut.2025.1539587] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/04/2024] [Accepted: 03/26/2025] [Indexed: 05/02/2025] Open
Abstract
Background The interaction mechanisms between obesity and psychological factors are intricate and bidirectional. Psychological issues can prompt unhealthy eating behaviors, impede weight management efforts, and elevate the risk of obesity. This study employs bibliometric approaches to conduct a comprehensive analysis of the knowledge structure, research hotspots, and development trends in the field of obesity and psychology, offering valuable references for future research in this area. Methods This study draws on the Web of Science Core Collection (WoSCC) database, with "obesity" and "psychology" serving as the primary search terms. Leveraging CiteSpace (version 6.3.R1) and VOSviewer (version 1.6.20) software, bibliometric analyses were conducted on various indicators, including the number of publications, publication volume, authors, journals, references, countries, institutions, and keywords. Through co-citation analysis and keyword co-occurrence analysis, the research hotspots and developmental trajectories in this field were revealed. Results Based on the inclusion and exclusion criteria, a total of 2,753 relevant articles were ultimately included in this study. The results indicate that since the 21st century, there has been a significant surge in the number of publications in the field of obesity and psychology. Developed countries like the United States, Canada, the United Kingdom, and Australia are at the forefront of this field. Leading research institutions include Yale University, University College London, and the University of Pennsylvania. Among the authors, GRILO CM has the highest publication output. Research hotspot keywords primarily include "depression," "stress," "emotional eating," "bariatric surgery," "intervention," "weight stigma," and "self-regulation." Current research trends reveal a marked regional imbalance in international collaboration in the field of obesity and psychology. In particular, there exists a notable absence of substantive cooperation between developed and developing countries. Research hotspots mainly center around the following aspects: Firstly, it focuses on the prevalence of common psychological distress symptoms, including depression, anxiety, and stress, within the obese population and the implications these symptoms have for health. Secondly, mental health issues like binge eating and emotional eating play a pivotal role in the onset and maintenance of obesity. Thirdly, psychosocial factors like health-related quality of life and weight stigma are at the core of obesity intervention and have potential impacts on behavioral change. Meanwhile, researchers are increasingly concentrating on the individualized mental health requirements of obese populations, emphasizing the importance of evidence-based psychological interventions in the management of obesity. These research hotspots not only enhance our understanding of the complex relationship between obesity and mental health but also provide crucial theoretical foundations and practical insights for future research directions. Conclusion This study employs bibliometric approaches to conduct a comprehensive and in-depth analysis of research trends and developments in the field of obesity and psychology. The research reveals the current status and characteristics of this field from multiple perspectives, offering scientific backing for researchers to identify potential collaborators, pinpoint hotspot issues, and keep abreast of the latest developments. Looking forward to the future, related research can further expand data sources, diversify research viewpoints, and delve more profoundly into the complex relationship between obesity and mental health.
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Affiliation(s)
| | | | | | | | | | - Guixiang Sun
- College of Traditional Chinese Medicine, Hunan University of Traditional Chinese Medicine, Changsha, China
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Tian T, Han H, Guan ZH, Zhang K, Huang X, Wang W, Zhang X, Zhang F, Wei L, Zhang X, Wang JH. A systematic review of hypervirulent Klebsiella pneumoniae research: bibliometric and topic modeling perspectives. Front Med (Lausanne) 2025; 12:1545678. [PMID: 40291031 PMCID: PMC12021593 DOI: 10.3389/fmed.2025.1545678] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/15/2024] [Accepted: 03/10/2025] [Indexed: 04/30/2025] Open
Abstract
Background/objective Hypervirulent Klebsiella pneumoniae (hvKP) is an emerging global health threat, exhibiting increased virulence and multidrug resistance compared to classic K. pneumoniae. Understanding the research landscape surrounding hvKP is crucial for developing effective control strategies. This study aimed to comprehensively analyze the global research trends in hvKP from 2013 to 2024 using bibliometric and topic modeling techniques. Methods Data from 1,014 articles on hvKP, retrieved from the Web of Science Core Collection, were analyzed using Bibliometrix, CiteSpace, and VOSviewer to assess publication trends, collaborations, geographical distribution, and keyword co-occurrence. Latent Dirichlet Allocation (LDA) topic modeling was employed to identify key research themes. Results The analysis revealed a steadily increasing volume of hvKP research, with China and the United States as major contributors. Four primary research themes emerged: high virulence phenotypes and mechanisms; drug resistance and treatment strategies; genetic and molecular mechanisms; and epidemiological and transmission characteristics. Research hotspots included virulence mechanisms, drug resistance, genomic detection approaches, and epidemiological features. Conclusion This bibliometric analysis provides a comprehensive overview of hvKP research, highlighting key trends and research gaps. The identified research hotspots inform future research directions and contribute to the development of effective strategies for combating hvKP infections. The increasing research volume underscores the urgent need for continued investigation into this significant public health threat.
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Affiliation(s)
- Tian Tian
- Department of Family Medicine, Shengjing Hospital of China Medical University, Shenyang, China
| | - Hui Han
- Science and Technology Research Center of China Customs, Beijing, China
| | - Zhi-Hui Guan
- Department of Developmental Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, China Medical University, Shenyang, China
| | - Ke Zhang
- Department of Developmental Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, China Medical University, Shenyang, China
| | - Xinghe Huang
- College of Metrology and Measurement Engineering, China Jiliang University, Hangzhou, China
| | - Wenyue Wang
- Department of General Practice, The First Hospital of China Medical University, Shenyang, China
| | - Xuan Zhang
- Department of Family Medicine, Shengjing Hospital of China Medical University, Shenyang, China
| | - Fei Zhang
- Department of Family Medicine, Shengjing Hospital of China Medical University, Shenyang, China
| | - Leijia Wei
- Department of Family Medicine, Shengjing Hospital of China Medical University, Shenyang, China
| | - Xin Zhang
- Department of Infection Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China
| | - Jia-He Wang
- Department of Family Medicine, Shengjing Hospital of China Medical University, Shenyang, China
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30
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Han Q, Wang H, Wang K, Fu Y, Li Z, Guan X, Guo H, Zhang C. Global landscape and hotspot analysis of meditation research in cancer: a bibliometric study. J Cancer Surviv 2025:10.1007/s11764-025-01784-7. [PMID: 40186798 DOI: 10.1007/s11764-025-01784-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/25/2024] [Accepted: 03/14/2025] [Indexed: 04/07/2025]
Abstract
PURPOSE Meditation is well known for its positive effects on recovery and quality of life enhancement among cancer patients. Meditation as an adjuvant therapy has received extensive attention from international scholars in relieving pain, reducing psychological pressure and improving the quality of life of cancer patients. In this study, we examine the current status of meditation in cancer research and its potential application value and future development. METHODS We collected 825 articles published in the Web of science Core Collection between January 1, 1976, and July 1, 2024, covering 11 cancer types. Bibliometric tools such as VOSviewer, Citespace, and Biblioshiny were used to analyze publication trends, international collaborations, author contributions, keywords, co-citations, and journal impact. RESULTS First, the steadily rising number of publications indicates an increasing scholarly focus on meditation's benefits for patients. Second, the USA, Australia, and China are the countries with the highest number of publications in each of the three clusters. Additionally, Carlson Linda E and eight other scholars are influential scholars in this field. Finally, through keyword co-occurrence and co-citation analysis, we identified "breast cancer," "quality of life," and "psychological intervention" as the hot topics of current research. CONCLUSIONS The study provides a valuable reference for scientific researchers to further explore meditation in cancer treatment. IMPLICATIONS FOR CANCER SURVIVORS This study highlights the growing interest in meditation as an adjuvant therapy for cancer patients, underscoring its potential to improve survivors' quality of life. Current research primarily focuses on quality of life, mindfulness-based stress reduction therapy, and clinical trials. Additionally, online, virtual reality technology, cancer survivors, fear of cancer recurrence, and qualitative research may become cutting-edge research directions in the future.
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Affiliation(s)
- Qi Han
- Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
- Shanxi Province Clinical Medical Research Center for Precision Medicine of Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
| | - Haiyan Wang
- Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China
- Shanxi Province Clinical Medical Research Center for Precision Medicine of Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China
- Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, The First Clinical Medical College of Shanxi Medical University, Taiyuan, 030001, China
| | - Kexin Wang
- Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China
- Shanxi Province Clinical Medical Research Center for Precision Medicine of Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China
- Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, The First Clinical Medical College of Shanxi Medical University, Taiyuan, 030001, China
| | - Yang Fu
- Department of Cardiology, Shanxi Cardiovascular Hospital, Taiyuan, 030024, China
| | - Zhongxun Li
- Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China
- Shanxi Province Clinical Medical Research Center for Precision Medicine of Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China
| | - Xiaoya Guan
- Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China
- Shanxi Province Clinical Medical Research Center for Precision Medicine of Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China
| | - Huina Guo
- Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China
- Shanxi Province Clinical Medical Research Center for Precision Medicine of Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China
| | - Chunming Zhang
- Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
- Shanxi Province Clinical Medical Research Center for Precision Medicine of Head and Neck Cancer, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
- Department of Otolaryngology Head & Neck Surgery, First Hospital of Shanxi Medical University, Taiyuan, 030001, China.
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Li M, Meng L, Gu H, Tian Y, Qu B, Ao Y, Chen X, Song Y, Cui W. B vitamins and colorectal cancer: exploring research hotspots and frontiers from a bibliometric and visual analysis (1994-2024). Carcinogenesis 2025; 46:bgaf021. [PMID: 40243145 DOI: 10.1093/carcin/bgaf021] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/11/2025] [Revised: 03/24/2025] [Accepted: 04/10/2025] [Indexed: 04/18/2025] Open
Abstract
Most studies suggest that B vitamins can reduce the risk of colorectal cancer (CRC), and research in this field has been growing. Focusing on 2617 articles in the field, this study used CiteSpace and VOSviewer software to evaluate the contributions of various countries/regions, institutions, authors, and journals. The United States and Harvard University were identified as the most productive nation and institution, respectively, with Edward L. Giovannucci (Harvard) being the top contributor. Cancer Epidemiology Biomarkers & Prevention was recognized as the leading journal. Through the analysis of keywords and citations, we found that the potential of B vitamins (B1, B2, B6, B9, and B12) in the prevention and treatment of CRC and their mechanisms including regulation of gene expression, anti-inflammatory and antioxidant, and modulation of gut microenvironment are hot topics of research in this field. Burst detection analysis further revealed that the application of nanoparticle-based targeted drug delivery systems (such as folate-conjugated nanocarriers) in the treatment of CRC represents both a current hotspot and a future trend. This study offers a comprehensive overview of the field, highlights research hotspots and trends, and offers valuable information for researchers to further grasp the research direction.
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Affiliation(s)
- Meichen Li
- Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun, China
| | - Lingshi Meng
- Department of Cardiology, Jilin Province People's Hospital, Changchun, China
| | - Hong Gu
- Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun, China
| | - Yuan Tian
- Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun, China
| | - Boyang Qu
- Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun, China
| | - Yanrong Ao
- Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun, China
| | - Xingyang Chen
- Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun, China
| | - Yuan Song
- Department of Gastroenterology, Jilin Province People's Hospital, Changchun, China
| | - Weiwei Cui
- Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun, China
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Zhang H, Chen H, Guo G, Lin J, Chen X, Huang P, Lin C, Lin H, Lu Y, Lin J, Li X, Zhang W. Nanotechnology in prostate cancer: a bibliometric analysis from 2004 to 2023. Discov Oncol 2025; 16:451. [PMID: 40175778 PMCID: PMC11965044 DOI: 10.1007/s12672-025-02265-0] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 12/11/2024] [Accepted: 03/28/2025] [Indexed: 04/04/2025] Open
Abstract
BACKGROUND Prostate cancer (PC) contributes to male mortality worldwide. The objective of this study is to comprehensively depict the scientific accomplishments and research trends in nanotechnology for PC applications. METHODS Utilizing the Web of Science Core Collection database, publications were gathered on the basis of inclusion and selection criteria. The publications were analyzed and visualized using VOSviewer, R-studio and CiteSpace software tools. RESULTS A total of 1949 studies were incorporated. Farokhzad was the most productive author. The United States and China released 58.13% of the total publications. The Chinese Academy of Sciences was the most influential institution, and the International Journal of Nanomedicine stood out as a prominent journal in this field. The most frequently referenced publication and research subject category were identified. The most extensively investigated area was nanoparticle-based drug delivery, while recent research has focused on anticancer with novel nanocarriers. CONCLUSION A bibliometric analysis in the PC and nanotechnology was conducted between 2004 and 2023. The overview and characteristics of the publications were identified. We discussed the application and restrictions faced by nanotechnology in PC management. The study of nanotechnology in PC treatment needs to be further studied.
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Affiliation(s)
- Hui Zhang
- Department of Urology, Jieyang People's Hospital, Jieyang, 522000, Guangdong, People's Republic of China
| | - Hongpeng Chen
- Department of Oncology, Jieyang People's Hospital, Jieyang, 522000, Guangdong, People's Republic of China
| | - Gaowei Guo
- Department of Urology, Jieyang People's Hospital, Jieyang, 522000, Guangdong, People's Republic of China
| | - Jinming Lin
- Department of Urology, Jieyang People's Hospital, Jieyang, 522000, Guangdong, People's Republic of China
| | - Xiaosheng Chen
- Department of Urology, Jieyang People's Hospital, Jieyang, 522000, Guangdong, People's Republic of China
| | - Peidong Huang
- Department of Urology, Jieyang People's Hospital, Jieyang, 522000, Guangdong, People's Republic of China
| | - Chuqi Lin
- Department of Urology, Jieyang People's Hospital, Jieyang, 522000, Guangdong, People's Republic of China
| | - Huirong Lin
- Department of Urology, Jieyang People's Hospital, Jieyang, 522000, Guangdong, People's Republic of China
| | - Yong Lu
- Department of Urology, Jieyang People's Hospital, Jieyang, 522000, Guangdong, People's Republic of China
| | - Jieming Lin
- Department of Operating Room, Jieyang People's Hospital, Jieyang, 522000, Guangdong, People's Republic of China
| | - Xinji Li
- Department of Urology, Jieyang People's Hospital, Jieyang, 522000, Guangdong, People's Republic of China.
| | - Wei Zhang
- Department of Urology, Jieyang People's Hospital, Jieyang, 522000, Guangdong, People's Republic of China.
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Miltenberg B, Johns WL, Baumann AN, Pottayil F, Richey B, Anastasio AT, Walley KC, Dodson CC, Hammoud S. Academic Productivity at Orthopaedic Surgery Sports Medicine Fellowship Programs in the United States Has a Weak Positive Correlation With Nonresearch Lifetime Industry Earnings. Arthrosc Sports Med Rehabil 2025; 7:101042. [PMID: 40297068 PMCID: PMC12034064 DOI: 10.1016/j.asmr.2024.101042] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/07/2024] [Accepted: 10/23/2024] [Indexed: 04/30/2025] Open
Abstract
Purpose To characterize the relationship between academic productivity, as defined by the h-index, and industry payments for fellowship-trained sports medicine surgeons in faculty positions at sports medicine fellowships. Methods The American Orthopaedic Society for Sports Medicine fellowship directory was used to create a comprehensive list of all fellowship programs nationwide. Fellowship websites were then reviewed to generate a list of the teaching faculty associated with each program. Total nonresearch lifetime earnings were obtained from the Centers for Medicare & Medicaid Services website. Academic productivity of each fellowship faculty was assessed via the h-index. Frequency counts and other descriptive statistic measures were used to describe the data for this study. Correlation was performed for continuous data using Spearman's ρ. Results Ninety orthopaedic surgery sports medicine fellowships were identified with a combined total of 574 orthopaedic surgery sports medicine fellowship faculty. There was a weak positive correlation between individual physician h-index and individual physician lifetime earnings at orthopaedic surgery sports medicine fellowships (P < .001; Spearman's ρ = 0.329). There was a statistically significant difference between individual faculty h-index by quartile and individual faculty lifetime earnings (test statistic: 47.3; P < .001). There was no significant regional difference in payments, but there is remarkable heterogeneity in the distribution of payments to individual physicians, with the top 10% of physicians receiving over 80% of industry dollars. Conclusions There is a positive correlation between academic productivity and industry payments at both the individual and institutional levels in orthopaedic sports medicine departments, although this relationship was greater at the fellowship level. Furthermore, the majority of nonresearch industry funding goes to a minority of physicians. Clinical Relevance Evaluating the impact that nonresearch industry payments have on a sports medicine orthopaedic surgeon's research productivity can offer valuable insights into the relationship between industry compensation and scholarly output in this field.
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Affiliation(s)
- Benjamin Miltenberg
- Rothman Institute at Thomas Jefferson University, Philadelphia, Pennsylvania, U.S.A
| | - William L. Johns
- Rothman Institute at Thomas Jefferson University, Philadelphia, Pennsylvania, U.S.A
| | - Anthony N. Baumann
- College of Medicine, Northeast Ohio Medical University, Rootstown, Ohio, U.S.A
| | - Faheem Pottayil
- Medical College of Georgia, Augusta University, Augusta, Georgia, U.S.A
| | - Bradley Richey
- Department of Orthopedic Surgery, University of Michigan, Ann Arbor, Michigan, U.S.A
| | - Albert T. Anastasio
- Department of Orthopedic Surgery, Duke University, Durham, North Carolina, U.S.A
| | - Kempland C. Walley
- Department of Orthopedic Surgery, University of Michigan, Ann Arbor, Michigan, U.S.A
| | | | - Sommer Hammoud
- Rothman Institute at Thomas Jefferson University, Philadelphia, Pennsylvania, U.S.A
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Reitblat O, Lerman TT, Dadon J, Zlatkin R, Bahar I, Sella R. Academic Productivity in Ophthalmology and Its Correlation to National Economic Indicators Among the OECD Countries: A Bibliometric Analysis. Ophthalmic Epidemiol 2025; 32:236-244. [PMID: 38718101 DOI: 10.1080/09286586.2024.2343728] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/22/2023] [Revised: 01/05/2024] [Accepted: 04/10/2024] [Indexed: 03/14/2025]
Abstract
PURPOSE Prompted by the clinical concern that limited healthcare resources allocation affects physicians' research productivity, this study examines the association between bibliometric indices of ophthalmologic research and national economic indicators in Organisation for Economic Co-operation and Development (OECD) countries. METHODS The Scimago Journal and Country rank source was searched for research productivity data in ophthalmology among OECD countries between 1996 and 2019. Bibliometric indices included: documents number, number and percent of citable documents, citations number, citations per document, and H-index. The updated economic indicators of each country (gross domestic product [GDP] per capita, health spending as percent of GDP (health expenditure), gross domestic expenditure on research, and development as percent of GDP [GERD]) were collected from the World Bank and the OECD websites. Correlation between economic and bibliometric metrics and multivariate linear regression analyses were performed. RESULTS Among 267,444 documents analyzed, correlation analysis found a strong correlation between health expenditure and H index (r = 0.711, p < 0.001); a moderate correlation between health expenditure and documents number (r = 0.589, p < 0.001), number of citable document (r = 0.593, p < 0.001) and citations number (r = 0.673, p < 0.001); and a moderate correlation between GERD and H index (r = 0.564, p < 0.001). Multivariate regression analysis controlling for economic factors, population and language showed the independent association of these parameters with bibliometric indices. CONCLUSIONS This study demonstrates a positive correlation between bibliometric indicators of ophthalmology research and economic factors, particularly health expenditure, among the OECD countries. Our results suggest an advantage of domestic investment in health to expand academic productivity in the field of ophthalmology.
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Affiliation(s)
- Olga Reitblat
- Department of Ophthalmology, Rabin Medical Center, Petah Tikva, Israel
- Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
| | - Tsahi T Lerman
- Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
- Department of Internal Medicine F-Recanati, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel
| | - Judith Dadon
- Department of Ophthalmology, Rabin Medical Center, Petah Tikva, Israel
- Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
| | - Rita Zlatkin
- Department of Ophthalmology, Rabin Medical Center, Petah Tikva, Israel
- Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
| | - Irit Bahar
- Department of Ophthalmology, Rabin Medical Center, Petah Tikva, Israel
- Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
| | - Ruti Sella
- Department of Ophthalmology, Rabin Medical Center, Petah Tikva, Israel
- Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
- Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA
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Hassan W, Abdelwahab SI, Taha MME, Farasani A, Jerah AA, Abdullah SM, Aljahdali IA, Oraibi B, Alfaifi HA, Alzahrani AH, Oraibi O, Babiker Y. From Data to Recommendations: A Comprehensive Review of Ten Bibliometric Papers in Aesthetic Plastic Surgery. Aesthetic Plast Surg 2025; 49:2269-2280. [PMID: 39623227 DOI: 10.1007/s00266-024-04518-9] [Citation(s) in RCA: 3] [Impact Index Per Article: 3.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/26/2024] [Accepted: 11/04/2024] [Indexed: 05/14/2025]
Abstract
This study provides a comprehensive analysis of ten papers published in Aesthetic Plastic Surgery, focusing on the identification of critical gaps and the integration of diverse analytical approaches. Through a detailed review, we observed missing indicators such as comprehensive bibliometric metrics and qualitative assessments of research impact. The findings underscore the need for a more balanced approach in future studies, combining quantitative bibliometric data with qualitative evaluations to provide a fuller understanding of the research landscape. Our analysis highlights the importance of integrating systematic reviews and meta-analyses to achieve a holistic view of the subject matter. By adopting diverse indicators and methodologies, researchers can better capture the multifaceted nature of the field, including the impact on patient care and treatment outcomes. We emphasize the necessity for authors and reviewers to clearly understand and define the main theme and objectives of their studies, avoiding potential confusion that may arise from mixing different analytical methods. Incorporating these recommendations will enhance the clarity and effectiveness of research in aesthetic plastic surgery, bridging the gap between academic metrics and practical applications. This approach aims to foster more informed advancements in the field, ultimately contributing to improved patient outcomes and a deeper understanding of aesthetic practices.No Level Assigned This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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Affiliation(s)
- Waseem Hassan
- Institute of Chemical Sciences, University of Peshawar, Peshawar, 25120, Khyber Pakhtunkhwa, Pakistan.
| | | | | | - Abdullah Farasani
- Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Jazan, Saudi Arabia
| | - Ahmed Ali Jerah
- Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Jazan, Saudi Arabia
| | - Saleh M Abdullah
- Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Jazan, Saudi Arabia
| | - Ieman A Aljahdali
- Department of Clinical Laboratory Sciences, Taif university, Taif, Saudi Arabia
| | - Bassem Oraibi
- Health Research Center, Jazan University, Jazan, Saudi Arabia
| | - Hassan Ahmad Alfaifi
- Pharmaceutical Care Administration (Jeddah Second Health Cluster), Ministry of Health, Jeddah, Saudi Arabia
| | - Amal Hamdan Alzahrani
- Department of Pharmacology and Toxicology, College of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia
| | - Omar Oraibi
- Department of Internal Medicine, Faculty of Medicine, Jazan University, Jazan, Saudi Arabia
| | - Yasir Babiker
- Department of Surgery, Faculty of Medicine, Jazan University, Jazan, Saudi Arabia
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Cheah PY, Parker M. Call for a fairer approach to authorship in publishing biomedical research. COMMUNICATIONS MEDICINE 2025; 5:99. [PMID: 40169787 PMCID: PMC11961711 DOI: 10.1038/s43856-025-00815-9] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/14/2024] [Accepted: 03/20/2025] [Indexed: 04/03/2025] Open
Abstract
In this Perspective article, we call for a fairer approach to authorship practice in collaborative biomedical research to promote equity and inclusiveness. Current practice does not adequately recognise all contributors involved in different stages of the work and may exacerbate preexisting inequalities. Here, we discuss some key features of contemporary collaborative research practice that complicate authorship decisions. These include the project size, complexity of multidisciplinary team involvement and researchers having varying degrees of expertise and experience. We conclude by making some suggestions to address these concerns.
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Affiliation(s)
- Phaik Yeong Cheah
- Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
- Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
| | - Michael Parker
- Ethox Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK
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37
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Holly LT. Building a Career in Academic Medicine: The Importance of Research and Publishing Your Data. Neurosurgery 2025; 96:701-703. [PMID: 40084894 DOI: 10.1227/neu.0000000000003363] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/15/2024] [Accepted: 12/16/2024] [Indexed: 03/16/2025] Open
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Huang N, Zou K, Liu F, Su Z, Chen L, Zhong Y, Luo Y, Wang M, Xiao L. Research trends and hotspots in post-stroke speech rehabilitation: A bibliometric analysis. Acta Psychol (Amst) 2025; 254:104781. [PMID: 39938389 DOI: 10.1016/j.actpsy.2025.104781] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/18/2024] [Revised: 01/31/2025] [Accepted: 02/05/2025] [Indexed: 02/14/2025] Open
Abstract
BACKGROUND With the global population aging, the incidence of stroke is rising, often resulting in motor dysfunction, speech disorders, and swallowing difficulties, significantly affecting daily life and social participation. Speech and language disorders notably impair communication and restrict social engagement, making speech rehabilitation a critical intervention. However, comprehensive bibliometric analyses on post-stroke language rehabilitation are limited, restricting understanding of progress in this field. OBJECTIVE This study aimed to identify hotspots and trends in post-stroke speech rehabilitation research from 2003 to 2023 to guide future studies. METHODS Articles on post-stroke speech rehabilitation from 2003 to 2023 were retrieved from the Web of Science Core Collection. Analyses included annual publications, key authors, countries, institutions, journals, co-citations, and keywords. RESULTS Among 1077 articles, publication volume showed an upward trend, with the United States leading in contributions. The Aphasiology journal published the most articles, and prominent institutions like the University of Queensland demonstrated significant publication and citation impact. Key trends included "communication disorders," "functional connectivity," and "melodic intonation therapy," with "stroke" and "aphasia" emerging as central keywords. CONCLUSION Research in post-stroke speech rehabilitation is increasing, with significant contributions from the United States and key institutions. Trends highlight the importance of communication-focused therapies and innovative techniques like melodic intonation therapy. This study provides insights into research directions.
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Affiliation(s)
- Nan Huang
- School of Rehabilitation Medicine, Gannan Medical University, Ganzhou City, Jiangxi Province 341000, People's Republic of China; Department of Rehabilitation Medicine, the First Affiliated Hospital of Gannan Medical University, Ganzhou City, Jiangxi Province 341000, People's Republic of China; Ganzhou Key Laboratory of Rehabilitation Medicine, Ganzhou City, Jiangxi Province 341000, People's Republic of China
| | - Kang Zou
- Department of Critical Care Medicine, the First Affiliated Hospital of Gannan Medical University, Ganzhou City, Jiangxi Province 341000, People's Republic of China
| | - Fang Liu
- School of Rehabilitation Medicine, Gannan Medical University, Ganzhou City, Jiangxi Province 341000, People's Republic of China; Department of Rehabilitation Medicine, the First Affiliated Hospital of Gannan Medical University, Ganzhou City, Jiangxi Province 341000, People's Republic of China; Ganzhou Key Laboratory of Rehabilitation Medicine, Ganzhou City, Jiangxi Province 341000, People's Republic of China
| | - Zhen Su
- School of Rehabilitation Medicine, Gannan Medical University, Ganzhou City, Jiangxi Province 341000, People's Republic of China; Department of Rehabilitation Medicine, the First Affiliated Hospital of Gannan Medical University, Ganzhou City, Jiangxi Province 341000, People's Republic of China
| | - Long Chen
- School of Rehabilitation Medicine, Gannan Medical University, Ganzhou City, Jiangxi Province 341000, People's Republic of China; Department of Rehabilitation Medicine, the First Affiliated Hospital of Gannan Medical University, Ganzhou City, Jiangxi Province 341000, People's Republic of China; Ganzhou Key Laboratory of Rehabilitation Medicine, Ganzhou City, Jiangxi Province 341000, People's Republic of China
| | - Yanbiao Zhong
- Department of Rehabilitation Medicine, the First Affiliated Hospital of Gannan Medical University, Ganzhou City, Jiangxi Province 341000, People's Republic of China; Ganzhou Key Laboratory of Rehabilitation Medicine, Ganzhou City, Jiangxi Province 341000, People's Republic of China; Ganzhou Intelligent Rehabilitation Technology Innovation Center, Ganzhou City, Jiangxi Province 341000, People's Republic of China
| | - Yun Luo
- Department of Rehabilitation Medicine, the First Affiliated Hospital of Gannan Medical University, Ganzhou City, Jiangxi Province 341000, People's Republic of China; Ganzhou Key Laboratory of Rehabilitation Medicine, Ganzhou City, Jiangxi Province 341000, People's Republic of China
| | - Maoyuan Wang
- Department of Rehabilitation Medicine, the First Affiliated Hospital of Gannan Medical University, Ganzhou City, Jiangxi Province 341000, People's Republic of China; Ganzhou Key Laboratory of Rehabilitation Medicine, Ganzhou City, Jiangxi Province 341000, People's Republic of China
| | - Li Xiao
- Department of Rehabilitation Medicine, the First Affiliated Hospital of Gannan Medical University, Ganzhou City, Jiangxi Province 341000, People's Republic of China; Ganzhou Key Laboratory of Rehabilitation Medicine, Ganzhou City, Jiangxi Province 341000, People's Republic of China; Ganzhou Intelligent Rehabilitation Technology Innovation Center, Ganzhou City, Jiangxi Province 341000, People's Republic of China.
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Reed F, Lyon M, Raspovic A, Marks P, Maguire S, Brennan L, Foldi CJ. Research metrics of Australian eating disorders researchers. J Eat Disord 2025; 13:57. [PMID: 40165247 PMCID: PMC11956253 DOI: 10.1186/s40337-025-01239-5] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 02/04/2025] [Accepted: 03/13/2025] [Indexed: 04/02/2025] Open
Abstract
Building the research capacity and capability of Australia's eating disorder (ED) research workforce has been identified as a key strategy to respond to the increasing prevalence of EDs. However, there is currently a limited understanding of the research strengths and scope of this workforce and this is a barrier to capacity building efforts and to evaluating the impacts of these efforts. This study sought to understand and summarise the current research metrics of the top 50 research experts in Australia identified through Expertscape. Publicly available publication, citation and funded research grants metrics, were extracted from Expertscape, Scopus, SciVal, Dimensions.ai and researcher profiles and summarised. The results indicate that Australian Feeding and Eating Disorder (FED) researchers are competitive internationally, and are spread across professional disciplines with the highest representation from psychology. Expertscape researcher rank was associated with higher numbers of publications in feeding and eating disorders overall, but not to total outputs, field-weighted citation impact (FWCI), or number of publications in top percentile journals. Publications were heavily focused on Anorexia Nervosa. Public grants awarded to the identified ED researchers in Australia over the past 10 years were largely National Health and Medical Research Council (NHMRC) project grant schemes, targeting innovative and creative research across any area of health and medical research. Cumulative dollars awarded over the 10-year period up to 2023 were approximately $23.9 million AUD, roughly 6 times less than that awarded to Schizophrenia research. These results summarise the current state of Australian FED research, comprised of a productive high performing research workforce limited by inadequate research funding.
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Affiliation(s)
- Felicia Reed
- Department of Physiology, Monash University, 26 Innovation Walk, Clayton, VIC, 3800, Australia
- Biomedicine Discovery Institute, Monash University, 23 Innovation Walk, Clayton, 3800, Australia
- Australian Eating Disorders Research & Translation Centre (AEDRTC), Sydney, NSW, Australia
| | - Maddy Lyon
- Department of Physiology, Monash University, 26 Innovation Walk, Clayton, VIC, 3800, Australia
| | - Anita Raspovic
- Australian Eating Disorders Research & Translation Centre (AEDRTC), Sydney, NSW, Australia
- School of Psychology & Public Health, Latrobe University, 133 McKoy Street, Wodonga, VIC, 3689, Australia
| | - Peta Marks
- Australian Eating Disorders Research & Translation Centre (AEDRTC), Sydney, NSW, Australia
- Charles Perkins Centre, Inside Out Institute, University of Sydney, Sydney, NSW, Australia
| | - Sarah Maguire
- Australian Eating Disorders Research & Translation Centre (AEDRTC), Sydney, NSW, Australia
- Charles Perkins Centre, Inside Out Institute, University of Sydney, Sydney, NSW, Australia
| | - Leah Brennan
- Australian Eating Disorders Research & Translation Centre (AEDRTC), Sydney, NSW, Australia
- School of Psychology & Public Health, Latrobe University, 133 McKoy Street, Wodonga, VIC, 3689, Australia
| | - Claire J Foldi
- Department of Physiology, Monash University, 26 Innovation Walk, Clayton, VIC, 3800, Australia.
- Biomedicine Discovery Institute, Monash University, 23 Innovation Walk, Clayton, 3800, Australia.
- Australian Eating Disorders Research & Translation Centre (AEDRTC), Sydney, NSW, Australia.
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40
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Li M, Livan G, Righi S. Quantifying the dynamics of peak disruption in scientific careers. Sci Rep 2025; 15:10812. [PMID: 40155420 PMCID: PMC11953407 DOI: 10.1038/s41598-025-95264-8] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/07/2023] [Accepted: 03/20/2025] [Indexed: 04/01/2025] Open
Abstract
We examine the disruption of researchers with long-lived careers in Computer Science and Physics. Despite the epistemological differences between such disciplines, we consistently find that a researcher's most disruptive publication does not occur at random during their career, as it cannot be explained by a null model. Such publication is accompanied by a peak year in which researchers publish other work that exhibits a higher level of disruption than average. Through a series of linear models, we show that the disruption achieved by a researcher during their peak year is higher when it is preceded by a long period of focus and low productivity. These findings are in stark contrast with the dynamics of academic impact. In these dynamics, researchers are incentivized by the prevalent paradigms of scientific evaluation to pursue high productivity and incremental-less disruptive-work, as evidenced by extensive literature.
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Affiliation(s)
- Mingtang Li
- Department of Computer Science, University College London, 66-72 Gower Street, London, WC1A 6EA, UK
| | - Giacomo Livan
- Department of Computer Science, University College London, 66-72 Gower Street, London, WC1A 6EA, UK.
- Department of Physics, University of Pavia, Via Bassi 6, 27100, Pavia, Italy.
- Sezione di Pavia, Istituto Nazionale di Fisica Nucleare, Via Bassi 6, 27100, Pavia, Italy.
| | - Simone Righi
- Department of Computer Science, University College London, 66-72 Gower Street, London, WC1A 6EA, UK
- Department of Economics "Marco Biagi", University of Modena and Reggio Emilia, Via Berengario 51, 41100, Modena, Italy
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41
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Lu S, Shen H, Li M, Luo Y, Sun H, Zhao X, Chen J, Bai R, Han P, Zha Y, Jiang X. Global knowledge mapping of receptor activator of nuclear factor kappa-B ligand in osteoporotic fractures: a bibliometric analysis (2001-2024). Front Mol Biosci 2025; 12:1545109. [PMID: 40206031 PMCID: PMC11978631 DOI: 10.3389/fmolb.2025.1545109] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/14/2024] [Accepted: 02/21/2025] [Indexed: 04/11/2025] Open
Abstract
Background Receptor activator of nuclear factor kappa-B ligand (RANKL) plays a critical role in bone metabolism and the pathogenesis of osteoporotic fractures. This study aims to conduct a bibliometric analysis of global research pertaining to RANKL and osteoporotic fractures to identify key trends, influential studies, and collaborative networks. Methods A literature search was conducted to identify articles found in the Web of Science Core Collection database regarding RANKL and osteoporotic fractures from 2001 to 2024. A bibliometric analysis was performed using VOSviewer, CiteSpace, and R 4.3.3 for the publication volume, country and institution contributions, journal impact, author influence, and research hotspots. Results A total of 214 articles were analyzed. Publication rates have steadily increased, with a peak of 21 papers in 2020. The U.S., China, and South Korea were the top contributing countries, and leading institutions included Harvard University and Dankook University. The Journal of Bone and Mineral Research, Osteoporosis International, and Bone were the journals of highest impact. At the level of authors, Heiss-Christian published the highest number and Christiansen-Claus had the strongest citation impact (1,368 citations). Research evolved from basic biological mechanisms (2001-2010) through clinical applications (2011-2017) to recent renewed interest in fundamental RANKL biology (2018-2024). Key research hotspots included postmenopausal osteoporosis, bone mineral density, and osteoclast differentiation, with emerging focus on RANKL's role beyond skeletal metabolism. Conclusion This bibliometric analysis provides a comprehensive overview of RANKL research in osteoporotic fractures, highlighting key priorities for future investigation. Future studies should prioritize understanding RANKL's broader physiological roles, developing better predictive markers, and optimizing personalized treatment strategies.
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Affiliation(s)
- Shuai Lu
- Department of Orthopedic Trauma, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China
- Beijing Research Institute of Traumatology and Orthopaedics, Beijing, China
| | - Huaishuang Shen
- Department of Orthopaedic Surgery, First Affiliated Hospital of Soochow University, Suzhou, China
| | - Minjuan Li
- Department of Orthopedic Trauma, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China
| | - Yiming Luo
- Geriatric Orthopedic, Shenzhen Pingle Orthopedic Hospital (Shenzhen Pingshan Traditional Chinese Medicine Hospital), Shenzhen, China
| | - Hao Sun
- Department of Orthopedic Trauma, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China
| | - Xian Zhao
- Department of Orthopedic Trauma, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China
| | - Jianming Chen
- Department of orthopedic, People’s Hospital of Lingcheng District, Dezhou, China
| | - Ruifeng Bai
- Department of Clinical Laboratory, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China
| | - Pengli Han
- Pharmaceutical Department, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China
| | - Yejun Zha
- Department of Orthopedic Trauma, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China
| | - Xieyuan Jiang
- Department of Orthopedic Trauma, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China
- Beijing Research Institute of Traumatology and Orthopaedics, Beijing, China
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Mwirigi D, Fekete-Farkas M, Borbély C. From Cow to Climate-Tracing the Path of Dairy Sustainability: Unveiling the Impact on Sustainable Development Goals Through Bibliometric and Literature Analyses. Animals (Basel) 2025; 15:931. [PMID: 40218325 PMCID: PMC11987737 DOI: 10.3390/ani15070931] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/07/2025] [Revised: 03/14/2025] [Accepted: 03/20/2025] [Indexed: 04/14/2025] Open
Abstract
Archeological evidence shows that dairy farming dates to the early Neolithic era in Europe, the Middle East, Asia, and Africa. Over time, it has evolved from domestication to intensive dairy farms with large, high-tech processing units. Dairy farming has contributed to economic growth, food production, employment, and processing industries. Nonetheless, it has been identified as a major contributor to climate change. This study explores the literature on dairy farming and sustainable development goals (SDGs) to identify current scholarly developments since the formulation and adoption of the SDGs in 2015 and themes for future research. This paper argues that sustainability shortfalls in dairy farming are primarily driven by human processes associated with commercialization and industrialization rather than the animals themselves, although biological emissions remain an inherent factor. Data were analyzed using R package, Excel, NVIVO, and VoS Viewer. A review of the literature showed that dairy farming and its contribution to sustainability has gained more scientific interest since 2015. Moreover, livestock management, feed production and management, stakeholder management, logistics and supply chain management, and waste management are the sources of environmental adversities associated with dairy farming. Notably, these are human processes developed from the commercialization of dairy farming and involve multiple stakeholders across the supply chain. While solutions are embedded within these processes, innovation emerges as a key driver of sustainability and a source of opportunities to strengthen sustainability in the dairy farming sector and achieve SDGs. Sustainability strategies, such as sustainable intensification, multifunctional agriculture, and agro-ecology should be implemented to improve sustainability in the dairy sector.
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Affiliation(s)
- Douglas Mwirigi
- Doctoral School of Economics and Regional Sciences, Hungarian University of Agriculture and Life Sciences, Páter Károly u. 1, 2100 Gödöllő, Hungary
| | - Mária Fekete-Farkas
- Institute of Agricultural and Food Economics, Hungarian University of Agriculture and Life Sciences, Páter Károly u. 1, 2100 Gödöllő, Hungary;
| | - Csaba Borbély
- Institute of Agricultural Economics and Food Economics, Hungarian University of Agriculture and Life Sciences, Páter Károly u. 1, 2100 Gödöllő, Hungary;
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Becerra-Patiño BA, Paucar-Uribe JD, Olivares-Arancibia J, Ojeda-Aravena A, Yáñez-Sepúlveda R, Gamonales JM, López-Gil JF, Hernández-Beltrán V. Mapping the Knowledge of Research Trends in Sports Performance Asymmetries from 2015 to 2024: A Bibliometric Study and Analysis of the Most-Cited Papers. Sports (Basel) 2025; 13:93. [PMID: 40278719 PMCID: PMC12031268 DOI: 10.3390/sports13040093] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/26/2025] [Revised: 03/06/2025] [Accepted: 03/20/2025] [Indexed: 04/26/2025] Open
Abstract
In recent years, studies related to preventing injuries and improving sports performance have aroused academic interest. However, no bibliometric study has investigated asymmetry. The aim of this study was twofold: (i) to identify trends in research on asymmetries in sports performance through bibliometric analysis, and (ii) to determine the most-cited articles to establish the main lines of research on asymmetries. The final sample consisted of 471 documents. The results show that, during the publication period, there was a considerable increase (73%) in research between 2020 and 2021, with 2022-2023 being the year with the highest production and number of citations. Most of the publications consisted of research articles (93.41%), with a low percentage of review studies (4.24%). The Journal of Strength and Conditioning Research and Symmetry were the journals with the highest number of documents (n = 57) and citations (n = 1230). The journals that produced the most knowledge were those in the first quartile (Q1) and the second quartile (Q2). The most prolific author was Bishop, C. The countries with the highest number of published documents were England (140 documents and 3039 citations) and the United States (94 documents and 2099 citations). The most common words in the studies were performance (n = 162), strength (n = 167), reliability (n = 118), injury (n = 94), and asymmetry (n = 90). The study of asymmetries in sports performance has focused on two main approaches: one related to analyzing differences between limbs, and the other focused on assessing strength after postoperative processes. The analysis of the existing body of knowledge on asymmetries allows us to incorporate the latest scientific advancements. In turn, this helps us to establish best practices to enhance both sports performance and rehabilitation processes.
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Affiliation(s)
- Boryi A. Becerra-Patiño
- Faculty of Physical Education, National Pedagogical University, Bogotá 110221, Colombia; (B.A.B.-P.); (J.D.P.-U.)
| | - Juan David Paucar-Uribe
- Faculty of Physical Education, National Pedagogical University, Bogotá 110221, Colombia; (B.A.B.-P.); (J.D.P.-U.)
| | - Jorge Olivares-Arancibia
- AFySE Group, Research in Physical Activity and School Health, School of Physical Education, Faculty of Education, Universidad de las Américas, Santiago 7500975, Chile;
| | - Alex Ojeda-Aravena
- Departamento de Ciencias de la Actividad Física, Universidad de Los Lagos, Osorno 1305, Chile;
| | - Rodrigo Yáñez-Sepúlveda
- Faculty Education and Social Sciences, Universidad Andres Bello, Viña del Mar 2520000, Chile;
| | - José M. Gamonales
- Training Optimization and Sports Performance Research Group (GOERD), Faculty of Sport Science, University of Extremadura, 10005 Cáceres, Spain; (J.M.G.); (V.H.-B.)
- Faculty of Education and Psychology, University of Extremadura, 06071 Badajoz, Spain
| | | | - Víctor Hernández-Beltrán
- Training Optimization and Sports Performance Research Group (GOERD), Faculty of Sport Science, University of Extremadura, 10005 Cáceres, Spain; (J.M.G.); (V.H.-B.)
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Xuan Q, Huang L, Gu W, Ling C. Twenty years of research on exercise-induced fatigue: A bibliometric analysis of hotspots, bursts, and research trends. Medicine (Baltimore) 2025; 104:e41895. [PMID: 40128028 PMCID: PMC11936639 DOI: 10.1097/md.0000000000041895] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/11/2024] [Accepted: 02/28/2025] [Indexed: 03/26/2025] Open
Abstract
Data from the Web of Science Core Collection (2004-2023) on "exercise-induced fatigue" were analyzed using bibliometric tools to explore research trends across countries, institutions, authors, journals, and keywords. The analysis was limited to "Article" and "Review" literature types. Among 4531 publications, the United States contributed the most articles (1005), followed by England (559) and China (516). The most influential institution was Universidade de São Paulo, while the most productive was Institut National de la Santé et de la Recherche Médicale with 103 papers. The European Journal of Applied Physiology ranked as the top journal with 233 articles. Millet Guillaume Y. emerged as the most prolific author, and Amann Markus was the most cited. Recent keyword trends showed a surge in terms like "physical activity" and "aerobic exercise," while "fatigue" and "exercise" remained dominant. Notable findings were observed in oncology, engineering, and multidisciplinary studies, indicating potential research trends. Oxidative stress was identified as the most commonly mentioned mechanism in exercise-induced fatigue studies. This bibliometric analysis highlights current research trends and gaps, suggesting that future studies should focus on understanding the mechanisms of exercise-induced fatigue, developing objective measurement criteria, and exploring strategies for its alleviation.
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Affiliation(s)
- Qiwen Xuan
- School of Traditional Chinese Medicine, Naval Medical University, Shanghai, China
| | - Lele Huang
- Department of Sports Medicine, Peking University Third Hospital, Institute of Sports Medicine of Peking University, Beijing, China
| | - Wei Gu
- School of Traditional Chinese Medicine, Naval Medical University, Shanghai, China
| | - Changquan Ling
- School of Traditional Chinese Medicine, Naval Medical University, Shanghai, China
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Gong Z, Liu Z, Zhu J, Zhao Z, Qiu J, Ying H, Peng Y, Gong L, Ye Y. Global research trends and hotspots on imaging of bladder cancer: A bibliometric and visual analysis from 1981 to 2023. Medicine (Baltimore) 2025; 104:e41907. [PMID: 40128048 PMCID: PMC11936662 DOI: 10.1097/md.0000000000041907] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/31/2024] [Accepted: 02/28/2025] [Indexed: 03/26/2025] Open
Abstract
There was currently no bibliometric analysis available regarding to bladder cancer (BCa) imaging. The aim of this study was to conduct a comprehensive bibliometric analysis of relevant literature on the imaging of BCa and elucidate global research hotspots and further trends in this field. All relevant literature on the imaging of BCa published between 1981 and 2023 were retrieved from the Web of Science Core Collection. VOSviewer, Bibliometrix, and Citespace were utilized for bibliometric analysis of publications, countries, authors, institutions, journals, references, and keywords. A total of 4462 articles were retrieved. The research in this field has been increasing consistently since 1981. The United States of America was the most productive country and most productive institutions were from it. Shariat SF was the most productive author with 36 articles and the author with the highest co-citations was Herr HW (472). Journal of Urology was the most productive journal and Frontiers in Oncology, Abdominal Radiology and Cancers exhibited heightened activity in recent years. A study by Siegel RL, published in CA-A Cancer Journal for Clinicians in 2019, had the highest number of co-citations. Further analysis of the keyword analysis and timeline view revealed that "radiomics," "deep learning," "multiparametric MRI," "VI-RADS," "muscle-invasive bladder cancer," "immunotherapy," and "long term outcome" were the most recent hotspots. In totally, in the period of 1981 to 2023 year, the USA occupies a critical position in the field of BCa imaging. It is anticipated that MRI-based imaging-reporting and data system and deep learning will be the research hotspots in the future.
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Affiliation(s)
- Zijian Gong
- Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China
- Intelligent Medical Imaging of Jiangxi Key Laboratory, Nanchang, China
| | - Zhixuan Liu
- Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China
- Intelligent Medical Imaging of Jiangxi Key Laboratory, Nanchang, China
| | - Jianghua Zhu
- Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China
- Intelligent Medical Imaging of Jiangxi Key Laboratory, Nanchang, China
| | - Zhen Zhao
- Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China
- Intelligent Medical Imaging of Jiangxi Key Laboratory, Nanchang, China
| | - Jia Qiu
- Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China
- Intelligent Medical Imaging of Jiangxi Key Laboratory, Nanchang, China
| | - Hongxin Ying
- Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China
- Intelligent Medical Imaging of Jiangxi Key Laboratory, Nanchang, China
| | - Yun Peng
- Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China
- Intelligent Medical Imaging of Jiangxi Key Laboratory, Nanchang, China
| | - Lianggen Gong
- Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China
- Intelligent Medical Imaging of Jiangxi Key Laboratory, Nanchang, China
| | - Yinquan Ye
- Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China
- Intelligent Medical Imaging of Jiangxi Key Laboratory, Nanchang, China
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Song K, Li S, Liu J, Kang Z. Global research trend of Herpes simplex keratitis: a bibliometric analysis and visualization from 1941 to 2024. Front Med (Lausanne) 2025; 12:1526116. [PMID: 40177280 PMCID: PMC11961934 DOI: 10.3389/fmed.2025.1526116] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/27/2024] [Accepted: 02/28/2025] [Indexed: 04/05/2025] Open
Abstract
Objective Herpes simplex keratitis (HSK), caused by the herpes simplex virus (HSV), is a leading cause of infectious blindness worldwide. This study aims to explore the research trends, key contributors, and emerging areas of focus in HSK research through bibliometric analysis. Methods Publications related to HSK from 1941 to 2024 were retrieved from the Web of Science Core Collection (WoSCC). Bibliometric and visual analyses were conducted using VOSviewer, CiteSpace, and R 4.3.3. Results A total of 1,076 publications on HSK were identified. The top three contributing countries were the United States (267 papers), China (99), and Japan (64). Harvard University was the leading institution with 75 publications, while the American Journal of Ophthalmology emerged as the most influential journal, boasting an h-index of 29. Kaufman, HE, was the most cited author, with 1,988 citations. The top three keywords were "infection" (82), "stromal keratitis" (73), and "penetrating keratoplasty" (62). Burst keyword analysis indicated a growing interest in terms such as "outcome" and "ultraviolet A" since 2018. Conclusion This bibliometric analysis underscores two primary research areas in HSK: the clinical management of stromal keratitis and infection, as well as the mechanisms of HSK recurrence, which include strategies for preventing reactivation and managing immune rejection. Future research is anticipated to focus on innovative treatments, particularly ultraviolet A therapy.
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Affiliation(s)
| | | | | | - Zefeng Kang
- China Academy of Traditional Chinese Medicine Hospital of Ophthalmology, Beijing, China
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Li S, Dong P, Wu X, Kang Z, Yan G. Global trends in tumor-associated neutrophil research: a bibliometric and visual analysis. Front Immunol 2025; 16:1478092. [PMID: 40160822 PMCID: PMC11949894 DOI: 10.3389/fimmu.2025.1478092] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/09/2024] [Accepted: 02/21/2025] [Indexed: 04/02/2025] Open
Abstract
Background Tumor-associated neutrophils (TANs) play crucial roles in tumor progression, immune response modulation, and the therapeutic outcomes. Despite significant advancements in TAN research, a comprehensive bibliometric analysis that objectively presents the current status and trends in this field is lacking. This study aims to fill this gap by visually analyzing global trends in TANs research using bibliometric and knowledge mapping techniques. Methods We retrieved articles and reviews related to TANs from the Web of Science core collection database, spanning the period from 2012 to2024. The data was analyzed using bibliometric tools such as Excel 365, CiteSpace, VOSviewer, and Bibliometrix (R-Tool of R-Studio) to identify key trends, influential countries and institutions, collaborative networks. and citation patterns. Results A total of 6l5 publications were included in the bibliometric analysis, showing a significant upward trend in TANs research over the last two decades. The United States and China emerged as the leading contributors with the highest number of publications and citations. The journal with the most publications in this field is Frontiers in Immunology, Prominent authors such as Fridlender ZG was identified as the key contributor, with his works frequently cited. The analysis highlighted major research themes. including the role of TANs in tumor microenvironment modulation, their dual functions in tumor promotion and suppression, and the exploration of TANs-targeted therapies, Emerging research hotspots include studies on TANs plasticity and their interactions with other immune cells. Conclusion This study is the first to employ bibliometric methods to visualize trends and frontiers in TANs research. The findings provide valuable insights into the evolution of the field, highlighting critical areas for future investigation and potential collaborative opportunities. This comprehensive analysis serves as a crucial resource for researchers and practitioners aiming to advance TAN research and its application in cancer therapy.
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Affiliation(s)
- Shaodong Li
- Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, China
| | - Peng Dong
- Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, China
| | - Xueliang Wu
- Department of General Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou, China
| | - Zhenhua Kang
- Department of Colorectal & Anal Surgery, General Surgery Center, First Hospital of Jilin University, Changchun, China
| | - Guoqiang Yan
- Department of Colorectal & Anal Surgery, General Surgery Center, First Hospital of Jilin University, Changchun, China
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Datt M, Sikora A, Henry K. Association Between Experienced Mentorship and Successful Publication of PGY1 Resident Research at an Academic Medical Center. Hosp Pharm 2025:00185787251326237. [PMID: 40092289 PMCID: PMC11907561 DOI: 10.1177/00185787251326237] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 03/19/2025]
Abstract
Purpose: ASHP Residency Standards consider research an important component of residency training. Publication of these projects is considered the gold standard for high quality research; however, residency research publication rates are low, with most reports suggesting less than 12% of projects are successfully published. This study reviewed post-graduate year one (PGY1) research projects to evaluate the role of mentorship in successful publication in peer-reviewed journals. Summary: This was a single-center, observational study of PGY1 research projects between 2010 and 2022 to assess mentorship's association with publication rate. Successful publication was confirmed via a PubMed search conducted through October 2022. Of 53 included PGY1 research projects, 18 projects (34%) were published, with 12 as manuscript publications and 6 as published abstracts. Projects with mentors with ≥3 publications and with mentors with ≥1 first author publications were associated with higher rates of full publications (excluding projects that were published in abstract form only) (50.0% vs 8.6%, p < 0.001; 37% vs 7.7%, p = 0.001). Faculty member participation also increased manuscript publication (63.6% vs 11.9%, p = 0.008). Publication of PGY1 projects was associated with higher rates of future publications (median 5 vs 1, p < .001). Conclusions: The presence of experienced mentors was associated with successful publication, and publishing a residency project was associated with future publications. New practitioners interested in precepting research projects may benefit from the inclusion of mentors with previous publication experience to support resident research projects.
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Affiliation(s)
| | - Andrea Sikora
- University of Georgia College of Pharmacy, Augusta, GA, USA
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Sun G, Wang L, Dong Z, Zhang Y, Yang Y, Hu M, Fang H. The Current Status, Hotspots, and Development Trends of Nanoemulsions: A Comprehensive Bibliometric Review. Int J Nanomedicine 2025; 20:2937-2968. [PMID: 40093547 PMCID: PMC11910037 DOI: 10.2147/ijn.s502490] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/07/2024] [Accepted: 02/20/2025] [Indexed: 03/19/2025] Open
Abstract
Nanoemulsions, which are characterized by their nanometer-scale droplets, have gained significant attention in different fields, such as medicine, food, cosmetics, and agriculture, because of their unique properties. With an increasing number of countries engaging in research on nanoemulsions, interest in their properties, preparation methods, and applications has increased. Hence, tracing the relevant research on nanoemulsions published in the past ten years on a global scale, by conducting data mining and visualization analysis on a sufficiently large text dataset through bibliometrics, sorting out and summarizing certain indicators, the development history, research status and research hotspots in the field of nanoemulsions can be clearly revealed, providing reference value and significance for subsequent research. This bibliometric review examines the research landscape of nanoemulsions from 2013-2023 via the SCI-E and SSCI databases, providing insights into the current status, hotspots, and future trends of this field. To offer a comprehensive overview, this analysis includes publication counts, author keywords, institutional contributions, research areas, prolific authors, highly cited papers and hot research papers. The findings reveal that China led in nanoemulsions research, followed by USA, India, and Brazil, with the University of Massachusetts emerging as a key player with the highest average number of citations per article (ACPP) and h-index. Food Chemistry, Pharmaceutics, and the Journal of Drug Delivery Science and Technology are among the top journals publishing in this area. Chemistry, pharmacology, and pharmacy emerged as the primary research domains, with McClements DJ as the most prolific and influential author. In keyword analysis, essential oil nanoemulsions are currently the main preparation direction, and various characteristics of nanoemulsions, such as their bioavailability, stability, biocompatibility, and antioxidant and antibacterial properties, have also been studied extensively. Research hotspots are focused mostly on the development of new applications and technologies for nanoemulsions.
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Affiliation(s)
- Guojun Sun
- Institute of Pharmaceutical Preparations, Department of Pharmacy, Zhejiang University of Technology, Hangzhou, People’s Republic of China
| | - Liying Wang
- Institute of Pharmaceutical Preparations, Department of Pharmacy, Zhejiang University of Technology, Hangzhou, People’s Republic of China
| | - Zuojun Dong
- Institute of Pharmaceutical Preparations, Department of Pharmacy, Zhejiang University of Technology, Hangzhou, People’s Republic of China
| | - Yanxiao Zhang
- Institute of Pharmaceutical Preparations, Department of Pharmacy, Zhejiang University of Technology, Hangzhou, People’s Republic of China
| | - Yan Yang
- Institute of Pharmaceutical Preparations, Department of Pharmacy, Zhejiang University of Technology, Hangzhou, People’s Republic of China
| | - Miao Hu
- Zhejiang Guangsha Vocational and Technical University of Construction, Jinhua, People’s Republic of China
| | - Hui Fang
- Library, Zhejiang University of Technology, Hangzhou, People’s Republic of China
- Institute of Information Resource, Zhejiang University of Technology, Hangzhou, People’s Republic of China
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50
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Chang X, Wang C, Zhang L. Research Trends of Tyrosine Kinase Inhibitors in EGFR-Mutated Non-Small Cell Lung Cancer: A Bibliometric Analysis. Drug Des Devel Ther 2025; 19:1703-1719. [PMID: 40093643 PMCID: PMC11910061 DOI: 10.2147/dddt.s510031] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/03/2024] [Accepted: 03/03/2025] [Indexed: 03/19/2025] Open
Abstract
Background This study seeks to identify research trends and hotspots concerning tyrosine kinase inhibitors (TKIs) for the treatment of epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) through a comprehensive bibliometric analysis. Methods Publications on TKIs and EGFR-mutated NSCLC from 2006 to 2024 were analyzed using VOSviewer, CiteSpace, and R-bibliometrix to visualize collaboration, keyword co-occurrences, and research trends. Results A total of 962 articles were analyzed, authored by 7,458 researchers from 5,401 institutions across 208 countries. Wu Yi-Long was identified as the most prolific author, contributing 30 publications. AstraZeneca emerged as the industrial leader with 103 articles, while the New England Journal of Medicine was recognized as the primary journal with the highest total link strength. Keyword co-occurrence analysis revealed significant research topics including "gefitinib", "chemotherapy", "open label", and "erlotinib." Moreover, keyword burst analysis indicated notable periods of increased research focus on topics such as "osimertinib" and "liquid biopsy", suggesting emerging trends and current hotspots in the treatment of EGFR-mutated NSCLC. Conclusion This analysis highlights research trends on TKIs for EGFR-mutated NSCLC, emphasizing the importance of targeted therapies like gefitinib and osimertinib for future research and clinical practice enhancement.
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Affiliation(s)
- Xiaoyan Chang
- Department of Thoracic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, People’s Republic of China
| | - Chenghao Wang
- Department of Thoracic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, People’s Republic of China
| | - Linyou Zhang
- Department of Thoracic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, People’s Republic of China
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