• CiteSpace
• VOSviewer
• VOSviewer bibliometric analysis
• bibliometric analysis
• perioperative
• rehabilitation

• bibliometric analysis
• biologics
• chronic rhinosinusitis
• collaboration
• frontier

• CiteSpace
• Postoperative ileus
• Scientometric analysis
• Trends
• VOSviewer
• Visualization

• CiteSpace
• HEN
• bibliometric analysis
• home enteral nutrition
• management

• bibliometric analysis
• exercise
• nutrition
• review
• sarcopenia

• bibliometrics
• bone-tendon interface
• enthesis
• trends
• visualization

• cochlear implant
• congenital heart disease
• etiology
• genetic counselling
• sensorineural hearing loss

• Child
• Humans
• Child, Preschool
• Retrospective Studies
• Hearing Loss, Sensorineural/complications
• Hearing Loss, Sensorineural/surgery
• Cochlear Implantation/adverse effects
• Cochlear Implants/adverse effects
• Heart Defects, Congenital/complications
• Heart Defects, Congenital/surgery

• CIFMS 2021-I2M-1-003 Chinese Academy of Medical Sciences
• 81974143 National Natural Science Foundation of China
• 2022-PUMCH-D-002 PUMCH National High-Level Hospital Clinical Research Funding

• PCSK9 inhibitors
• bibliometric analysis
• cardiovascular endocrinology
• data visualization
• hotspots
• trend

• Female
• Humans
• United States
• Proprotein Convertase 9
• PCSK9 Inhibitors
• Antibodies, Monoclonal, Humanized/therapeutic use
• Cholesterol, LDL
• Enzyme Inhibitors/therapeutic use
• Bibliometrics

• Natural Science Foundation of Hunan Province
• National Natural Science Foundation of China
• Key Research and Development Program of Hunan Province of China
• Health Commission of Hunan Province
• China Postdoctoral Science Foundation

• Bibliometrics
• CiteSpace
• Hepatocellular carcinoma
• Transarterial chemoembolization
• VOSviewer

• bibliometric analysis
• bronchiolitis obliterans
• collaboration
• global research trends
• research hotspots

• Humans
• Bronchiolitis Obliterans/diagnosis
• Bronchiolitis Obliterans/therapy
• Bronchiolitis Obliterans Syndrome
• Bibliometrics
• Cluster Analysis
• Databases, Factual

• Alzheimer’s disease
• CiteSpace
• VOSview
• Web of Science
• bibliometric
• mitochondrial dysfunction

Over the last two decades, mining and mineral processing (MMP) has changed dramatically. Little is known about the bibliometric analysis of MMP. To this end, this study used the big data analysis to investigate the quantity and quality of scientific outputs in MMP over the past 21-year timespan. This study used IBM SPSS Statistics 25.0 and VOSviewer software to research on the 20 journals from Science Citation Index Expanded (SCI-Expanded) of Web of Science Core Collection (WOSCC). VOSviewer software was used to identify the visualization contributions of scientific outputs over 21-year timespan. Totally, the big data analysis shows people of China have the highest cumulative IFs, but their mean IFs are relatively low and are ranked in fourth place. Visually, people of Chin ranked the first in total link strength (2967), but not in links (86), which is the third place among Top15 countries. From the perspective of quality, it cannot rank the first. Thus, people of China should put more effort into improving the quality of scientific outputs.

• CiteSpace
• VOSviewer
• bibliometric analysis
• frontiers trends
• hotspots
• low carbohydrate diet

Liver cirrhosis is the leading cause of liver-related mortality worldwide. It is currently a global health challenge.

This research intended to explore and analyse research trends and frontiers in this field during the last 10 years, providing new inspiration for clinical decision-making and scientific research.

Publications on hepatic cirrhosis research were retrieved from the Web of Science Core Collection on April 4, 2021. Bibliometric visualisation was conducted through VOSviewer and CiteSpace.

The analytic research was based on original articles and reviews. A total of 7775 records of hepatic cirrhosis published from 2011 to 2020 were retrieved. In the past ten years, the number of related annual publications has increased significantly, especially in the United States and China. All publications were distributed among 109 countries. The United States contributed the most (21.95%) and was consistently the leading driving force, with a solid academic reputation in this area. The University of Barcelona distributed the most related articles (177 articles) and was cited the most frequently. The Journal of Hepatology ranked third in the top 10 journals, which has the highest impact factor (impact factor 2019 = 20.582). Jasmohan S. Bajaj was the most productive author (72 articles). Burst keywords (e.g., sofosbuvir, burden, care, sarcopenia, chronic liver failure, human gut microbiome, and nonalcoholic fatty liver disease) and a succession of reference citation bursts have provided clues about research frontiers in recent years.

This study identified developing trends in the evolution of liver cirrhosis to provide new inspiration for researchers.

• Liver cirrhosis
• Bibliometric research
• Research frontiers
• VOSviewer
• CiteSpace
• Visualization

• Bibliometrics
• Efficiency
• Humans
• Liver Cirrhosis/diagnosis
• Liver Cirrhosis/therapy
• Publications
• Sofosbuvir
• United States

Pulmonary arterial hypertension (PAH) is a group of devastating and progressive disorders, resulting in relentless increases in pulmonary vascular resistance. The number of studies related to PAH has been increasing in recent years. Our study aims to illustrate trends in PAH research over the past decade using bibliometric analysis. Science Citation Index-Expanded was adopted to search studies concerning PAH between 2011 and 2020. The bibliographic information was converted and analyzed automatically using a bibliometric package in R software and citespace. The annual quantity of publications on PAH showed an overall increase last decade. The United States was the most prolific country with 2,479 publications, and it was also the country that cooperated most with other countries. Hôpital Bicêtre made important research achievements on PAH and was a leader in study cooperation. Marc Humbert led the PAH field by publishing 150 articles in the past decade. During the past decade, there was a close transnational relation among countries or regions, institutions and authors. Further, Circulation was the most cited journal, followed by the Journal of the American College of Cardiology and the American Journal of Respiratory and Critical Care Medicine, with 3,895, 3,406, and 3,170 citations, respectively. The global research status and trend of PAH are deeply understood for the first time using bibliometric and visual methods, and the results of our study bring us a valuable reference for clinical researchers.

This is the first study to illustrate trends in pulmonary arterial hypertension research using bibliometric analysis.

• Pulmonary arterial hypertension
• bibliometric analysis
• selexipag
• treprostinil
• visualization

Research on the treatment of chronic rhinosinusitis (CRS) has increased in recent decades. We undertook a bibliometric and visualization analysis of studies on CRS treatment to track research trends and highlight current research “hotspots”.

Original publications related to CRS treatment were obtained from the Science Citation Index-Expanded (SCI-E) and Social Sciences Citation Index (SSCI) databases in the Web of Science Core Collection (WoSCC) of Clarivate Analytics between 2001 and 2020. The country/region, institution, author, journal, references, and keywords involved in this topic were extracted using CiteSpace and VOSviewer to identify and analyze the research focus and trends in this field.

In the previous two decades (especially after 2015), the number of publications on CRS treatment has grown markedly. With regard to publications and access to collaborative networks, the leading country was the USA. High-frequency keywords were “CRS,” “endoscopic sinus surgery,” “sinusitis,” “nasal polyps,” “asthma,” “rhinosinusitis,” “management,” “diagnosis,” “outcomes,” and “quality of life.” Inspection of keyword bursts suggested that “clinical practice guideline,” “adult CRS,” “innate lymphoid cell,” “recurrence,” and “mepolizumab” are the emerging research hotspots. The timeline view of the cluster map revealed that biologic agents have become an up-and-coming “hot topic” in CRS treatment in recent years.

Academic understanding of CRS treatment has improved markedly over the past 20 years. We study analyzed the papers objectively, methodically, and comprehensively, and identified hotspots and prospective trends in the field of CRS treatment. These results will aid rhinologists in gaining greater insight into CRS treatment strategies and identifying the changing dynamics of CRS research.

• Guizhou Medical University

Given the increasing number and survival rates of reproductive-age patients with chronic myeloid leukemia (CML), several studies aimed to elucidate optimum disease management in pregnancy. This study aimed to use bibliometric analysis to assess focus and reported insights, as well as future trends, in CML and pregnancy research.

We extracted all studies related to CML and pregnancy from the Web of Science database from 2001 to 2020. VOS Viewer, CiteSpace, Python, and R-bibliometrix were used for bibliometric analysis, revealing the leading research countries, institutions, and authors, as well as distribution of keywords (frequency greater than five).

A total of 196 records, published in 137 journals by 1,105 authors from 421 research institutes in 50 countries, were identified for analysis. The United States was the leader in the number of publications. Imperial College London and National Research Center for Hematology were the most influential institutions. In addition, Apperley J, Cortes J, Abruzzese E and Kantarjian H were the leading authors in the field. Keyword analysis identified four research hotspot clusters.

This study systematically analyzed the progress in CML and pregnancy research in the last 20 years. The present findings suggest that the management of planned and unplanned pregnancies in patients with CML will remain a research focus, as further evidence is required for the development of treatment guidelines.

Physical exercise (PE) brings physiological benefits to human health; paradoxically, exposure to air pollution (AP) is harmful. Hence, the combined effects of AP and PE are interesting issues worth exploring. The objective of this study is to review literature involved in AP-PE fields to perform a knowledge-map analysis and explore the collaborations, current hotspots, physiological applications, and future perspectives. Herein, cluster, co-citation, and co-occurrence analysis were applied using CiteSpace and VOSviewer software. The results demonstrated that AP-PE domains have been springing up and in rapid growth since the 21st century. Subsequently, active countries and institutions were identified, and the productive institutions were mainly located in USA, China, UK, Spain, and Canada. Developed countries seemed to be the major promoters. Additionally, subject analysis found that environmental science, public health, and sports medicine were the core subjects, and multidimensional communications were forming. Thereafter, a holistic presentation of reference co-citation clusters was conducted to discover the research topics and trace the development focuses. Youth, elite athletes, and rural population were regarded as the noteworthy subjects. Commuter exposure and moderate aerobic exercise represented the common research context and exercise strategy, respectively. Simultaneously, the research hotspots and application fields were elaborated by keyword co-occurrence distribution. It was noted that physiological adaptations including respiratory, cardiovascular, metabolic, and mental health were the major themes; oxidative stress and inflammatory response were the mostly referred mechanisms. Finally, several challenges were proposed, which are beneficial to promote the development of the research field. Molecular mechanisms and specific pathways are still unknown and the equilibrium points and dose-effect relationships remain to be further explored. We are highly confident that this study provides a unique perspective to systematically and comprehensively review the pieces of AP-PE research and its related physiological mechanisms for future investigations.

• National Social Science Fund of China

This study explores the emerging trends and hot topics concerning applications on electrical impedance tomography (EIT) in clinical lung monitoring.

Publications on EIT applications in clinical lung monitoring in 2001–2021 were extracted from the Web of Science Core Collection (WoSCC). The search strategy was “electrical impedance tomography” and “lung.” CiteSpace, a VOS viewer was used to study the citation characteristics, cooperation, and keyword co-occurrence. Moreover, co-cited reference clustering, structural variation analysis (SVA), and future research trends were presented.

Six hundred and thirty-six publications were included for the final analysis. The global annual publications on clinical lung monitoring gradually increased in the last two decades. Germany contributes 32.2% of total global publications. University Medical Center Schleswig-Holstein (84 publications, cited frequency 2,205), Physiological Measurement (105 publications, cited frequency 2,056), and Inéz Frerichs (116 articles, cited frequency 3,609) were the institution, journal, and author with the largest number of article citations in the research field. “Electrical impedance tomography” (occurrences, 304), “mechanical ventilation” (occurrences, 99), and “acute respiratory distress syndrome” (occurrences, 67) were the top most three frequent keywords, “noninvasive monitoring” (Avg, pub, year: 2008.17), and “extracorporeal membrane oxygenation” (Avg, pub, year: 2019.60) were the earliest and latest keywords. The keywords “electrical impedance tomography” (strength 7.88) and co-cited reference “Frerichs I, 2017, THORAX” (strength 47.45) had the highest burst value. “Driving pressure,” “respiratory failure,” and “titration” are the three keywords still maintaining a high brush value until now. The largest and smallest cluster of the co-cited references are “obstructive lung diseases” (#0, size: 97) and “lung perfusion” (#20, size: 5). Co-cited reference “Frerichs I, 2017, THORAX” (modularity change rate: 98.49) has the highest structural variability. Categories with most and least interdisciplinary crossing are “ENGINEERING” and “CRITICAL CARE MEDICINE.”

EIT is a valuable technology for clinical lung monitoring, gradually converting from imaging techniques to the clinic. Research hot spots may continue monitoring techniques, the ventilation distribution of acute respiratory distress syndrome (ARDS), and respiratory therapy strategies. More diversified lung function monitoring studies, such as lung perfusion and interdisciplinary crossing, are potentially emerging research trends.

• Shanghai Jiao Tong University
• Shanghai Minhang Science and Technology Commission

• Tai Chi
• bibliometric analysis
• cognitive function
• research trends
• traditional Chinese health exercises

• Bibliometrics
• Canada
• China
• Cognition
• United States

• National Social Science Fund of China

• Female
• Humans
• Internship and Residency
• Prevalence
• Surgeons
• Surgery, Plastic/education
• United States
• Workforce

• COVID-19
• ECMO
• bibliometric study
• research trends and hotspots
• visualization analysis

• bibliometric analysis
• hotspots
• oncology
• radiomics
• trends

• Web of Science
• low back pain
• physical activity
• research trends

Background: High-intensity interval training (HIIT) is an emerging exercise strategy and is considered to be a recipe for health promotion. This study aimed to systematically identify collaboration networks, track research trends, highlight current hotspots, and predict future frontiers in HIIT and its applications in health promotion since the start of the new century.

Methods: Relevant original publications were obtained from the Science Citation Index Expanded of the Web of Science Core Collection (WoSCC) database between 2001 and 2020. CiteSpace and VOSviewer software were used to perform bibliometric visualization and comparative analysis of involved indexes that included countries, institutions, journals, authors, references, and keywords.

Results: A total of 572 papers were included, and the trend of annual publications showed a remarkable growth. The United States and the University of Exeter were the most productive country and institutions, respectively, with 107 and 18 publications, respectively. European Journal of Applied Physiology took the lead in the number of published articles, and Medicine and Science in Sports and Exercise ranked first in the cocitation counts. Barker AR and Gibala MJ were considered as the most productive and the most highly-cited authors.

Conclusions: “Health risks,” “adolescent,” and “aging” are the three noteworthy topics during the evolution of HIIT-health promotion (HIIT-HP) research. The current research hotspots of HIIT and its practices in the health promotion domain lies in “metabolic diseases,” “cardiovascular diseases,” “neurological diseases,” and “musculoskeletal diseases.” The authors summarize that “prevention and rehabilitation,” “micro and molecular level,” and “cognition and mental health” are becoming frontiers and focus on the health topics related to HIIT in the upcoming years, which are worthy of further exploration.

• CiteSpace
• VOSviewer
• bibliometric analysis
• health promotion
• high intensity interval training

• bibliometric
• depression
• exercise intervention
• teenagers
• visualization analysis

Background: For measuring their impact in scientific research, the citation count of the publications is used in the bibliometric analysis, though still in the bibliometric analysis, there is no comprehensive summary of mild traumatic brain injury (mTBI) research. This article intends to provide the physicians and the neuroscientists with a reference guide to assess the most influential publications written on this subject through a macroscopic view of the research activities on mTBI.

Methods: The database of the Web of Science was used to compile the 100 top-ranking publications on mTBI. The selected publications were evaluated on the basis of the several categorizations including the type of the publications, number of citations, country of origin, and year of publication.

Results: Between 1946 and 2020, the 13,040 publications that were published were included in the database. The least cited publications received 274 citations, while the most cited received 1,748. Altogether, 71 publications were from the USA while 29 were from other countries. Among all the institutions, the University of Pittsburgh Medical Center led the list with six publications. Around 100 papers, mostly on the clinical studies in the categories of neurology and neurosciences, were published in 54 different journals.

Conclusions: This study provides both a transverse section summary and historical retrospect for the clinical advances of mTBI, and the publications of important observations that contributed a significant impact on the treatment and prevention of mTBI had been identified.

• bibliometric analysis
• mild traumatic brain injury
• neurotrauma
• top-cited publications
• visualization

While studies on the health benefits of Tai Chi have sprung up over the past four decades, few have engaged in collecting global data, estimating the developing trends, and conducting reviews from the perspective of visualization and bibliometric analysis. This study aimed to provide a summary of the global scientific outputs on Tai Chi research from 1980 to 2020, explore the frontiers, identify cooperation networks, track research trends and highlight emerging hotspots. Relevant publications were downloaded from the Web of Science Core Collection (WoSCC) database between 1980 and 2020. Bibliometric visualization and comparative analysis of authors, cited authors, journals, co-cited journals, institutions, countries, references, and keywords were systematically conducted using CiteSpace software. A total of 1078 publications satisfied the search criteria, and the trend of annual related publications was generally in an upward trend, although with some fluctuations. China (503) and Harvard University (74) were the most prolific country and institution, respectively. Most of the related researches were published in the journals with a focus on sport sciences, alternative medicine, geriatrics gerontology, and rehabilitation. Our results indicated that the current concerns and difficulties of Tai Chi research are “Intervention method”, “Targeted therapy”, “Applicable population”, “Risk factors”, and “Research quality”. The frontiers and promising domains of Tai Chi exercise in the health science field are preventions and rehabilitations of “Fall risk”, “Cardiorespiratory related disease”, “Stroke”, “Parkinson’s disease”, and “Depression”, which should receive more attention in the future.

• Tai Chi
• bibliometric analysis
• exercise and health science
• visualization analysis

• Bibliometrics
• China
• Humans
• Publications
• Tai Ji

• NEBEOP
• bibliometrics
• congresses as topic
• graduate dental education
• orthodontics
• periodicals as topic

• Accreditation
• Bibliometrics
• Education, Dental
• Europe
• Humans
• Orthodontics
• Societies, Dental

• GDP
• Gross domestic product
• Iran
• PubMed
• Publications
• Publishing trend
• Scientific production

• VOSviewer
• bibliographic item co-occurrence matrix builder
• bibliometric analysis
• primary aldosteronism
• research hotspots

• Bibliometrics
• Biomedical Research/trends
• Humans
• Hyperaldosteronism/diagnosis
• Hyperaldosteronism/therapy
• Publications/statistics & numerical data
• Time Factors

• Long noncoding RNAs
• bibliometric study
• citation analysis
• lncRNAs
• top-cited

• bibliometrics
• citation
• robotics
• urology

• Bibliometric
• CiteSpace
• Functional near-infrared spectroscopy
• Web of science

• CiteSpace
• Web of Science
• bibliometrics
• citation burst
• frontiers
• rTMS

• Bibliometric
• Irish
• Publications
• Republic of Ireland
• Research

• Magnetic resonance
• bibliometric analysis
• citation
• citation classics
• publication

• Endourology
• Kidney stones
• Stone treatment
• Urolithiasis
• Web-based survey

• Anti-Bacterial Agents/therapeutic use
• Austria
• Female
• Germany
• Humans
• Kidney Calculi/therapy
• Laparoscopy/methods
• Lithotripsy/methods
• Male
• Middle Aged
• Nephrolithotomy, Percutaneous/methods
• Practice Patterns, Physicians'/statistics & numerical data
• Surveys and Questionnaires
• Switzerland
• Ureteroscopy/methods
• Urologic Surgical Procedures/methods
• Urologists

• East Asia
• Web of Science
• bibliometrics
• transplantation

• Bibliometrics
• China
• Humans
• Japan
• Journal Impact Factor
• Periodicals as Topic/statistics & numerical data
• Republic of Korea
• Socioeconomic Factors
• Taiwan
• Transplantation

• Bibliometric analysis
• Nephrology
• Research
• Urology

• bibliometric
• urology and nephrology
• arab world
• isi web of science

• Bibliometrics
• Biomedical Research/statistics & numerical data
• Cooperative Behavior
• Databases, Bibliographic
• Humans
• Middle East
• Nephrology/trends
• Periodicals as Topic
• Urology/trends