Synergistic mechanism of adipose-derived stem cells in healing diabetic foot ulcers

doi:10.4239/wjd.v17.i5.116210

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 17, Issue 5

This Article

(0) (0) (0)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (70)

All Articles published online

Item

Count

PDF

HTML

Figures (1-1)

Tables (1-1)

Sum=56

Publishing Process of This Article

Item

Count

Browse

Download

Sum=33

May 15, 2026 (publication date) through May 14, 2026

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Diabetes

ISSN

1948-9358

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Editorial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Diabetes. May 15, 2026; 17(5): 116210
Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.116210

Table 1 The application of mesenchymal stem cells in the diabetic foot ulcers

Type	Source	Pros	Cons	Recommended dose
BMSCs	Bone marrow	Theoretical safety; high differentiation effects	Low-yield invasive bone marrow aspiration in diabetics	Subcutaneous injection 9 × 10⁷ cells[53]
ADSCs	Adipose tissue	Abundant and easily extracted from adipose tissue; multipotent differentiation potential; display enhanced anti-inflammatory effects	Contamination risk from extraction	Subcutaneous injection 5 × 10⁵ cells[67]
UCMSCs	Human umbilical cord	Strong proliferative capacity and low immunogenicity	Ethical issues	Intravenous administrations 2 × 10⁵ cells/kg with an upper limit of 1 × 10⁷ cells[59]

BMSC: Bone marrow-derived mesenchymal stem cell; ADSC: Adipose-derived stem cell; UCMSC: Umbilical cord-derived mesenchymal stem cell.

Full Size Table

Citation: Wan XX, Yan WT, He WH, Xiong K. Synergistic mechanism of adipose-derived stem cells in healing diabetic foot ulcers. World J Diabetes 2026; 17(5): 116210
URL: https://www.wjgnet.com/1948-9358/full/v17/i5/116210.htm
DOI: https://dx.doi.org/10.4239/wjd.v17.i5.116210

Wan XX, Yan WT, He WH, Xiong K. Synergistic mechanism of adipose-derived stem cells in healing diabetic foot ulcers. World J Diabetes 2026; 17(5): 116210 [DOI: 10.4239/wjd.v17.i5.116210]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.