Prospective Study
Copyright ©The Author(s) 2017.
World J Diabetes. Jul 15, 2017; 8(7): 374-380
Published online Jul 15, 2017. doi: 10.4239/wjd.v8.i7.374
Figure 1
Figure 1 Increased concentration of bile acids caused to activation of farnesoid X receptor A and G protein-coupled bile acid receptor, these two receptors have adverse impact on different tissues. Activation of farnesoid X receptor A (FXRA) and G protein-coupled bile acid receptor (TGR5) can stimulate the secretion of glucagon-like peptide I and II (GLP), and GLP have positive effect on pancreas.