Visceral fat area and remnant cholesterol in type 2 diabetes: Nonlinear associations and thresholds

Figure 1 The dose-response patterns between visceral fat area and residual cholesterol/residual cholesterol-inflammation index using spline-based smoothing techniques. A: Smoothing spline curve for the association between visceral fat area (VFA) and residual cholesterol (RC); B: Smoothing spline curve for the association between VFA and the RC to C-reactive protein ratio (RC-inflammation index). The red line represents the fitted smoothing spline and the blue dotted lines represent the 95%CIs. Vertical ticks along the X-axis indicate the distribution of VFA. Models were adjusted for age, sex, current smoking, current drinking, glycated haemoglobin, free triiodothyronine, estimated glomerular filtration rate and alanine aminotransferase. RCII: Residual cholesterol-inflammation index.