Comparison of triglyceride-glucose index and its derived indices as markers for adverse pregnancy outcomes

Figure 1  Flowchart of participants selection.

Figure 2 Spearman correlations between triglyceride-glucose index and its derived indices with glycemic and lipid parameters. ^aP < 0.05. ^bP < 0.01. ^cP < 0.001. TC: Total cholesterol; TG: Triglycerides; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol; OGTT: Oral glucose tolerance test; HbA1c: Glycated hemoglobin; TyG: Triglyceride-glucose index; BMI: Body mass index; WC: Waist circumference; WHtR: Waist-to-height ratio.

Figure 3 Dose-response relationship of triglyceride-glucose and its derived indices with the risk of gestational diabetes mellitus, hypertensive disorders of pregnancy, cesarean delivery, and large for gestational age. A-D: Associations of triglyceride-glucose index (TyG), TyG-body mass index, TyG-waist circumference, and TyG-waist-to-height ratio with the risk of gestational diabetes mellitus; E-H: Associations of the four indices with the risk of hypertensive disorders of pregnancy; I-L: Associations of the four indices with the risk of cesarean delivery; M-P: Associations of the four indices with the risk of large for gestational age. GDM: Gestational diabetes mellitus; HDP: Hypertensive disorders of pregnancy; CD: Cesarean delivery; LGA: Large for gestational age; BMI: Body mass index; TyG: Triglyceride-glucose index; WC: Waist circumference; WHtR: Waist-to-height ratio.

Figure 4 Receiver operating characteristic curves of triglyceride-glucose and its derived indices for predicting adverse maternal and neonatal outcomes. A: Receiver operating characteristic (ROC) curves for gestational diabetes mellitus; B: ROC curves for hypertensive disorders of pregnancy; C: ROC curves for cesarean delivery; D: ROC curves for large for gestational age. GDM: Gestational diabetes mellitus; HDP: Hypertensive disorders of pregnancy; CD: Cesarean delivery; LGA: Large for gestational age; BMI: Body mass index; TyG: Triglyceride-glucose index; WC: Waist circumference; WHtR: Waist-to-height ratio; AUC: Areas under the curve.