Umbrella review protocol type 2 diabetes mellitus and fracture risk

doi:10.4239/wjd.v17.i4.116349

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Apr 15, 2026 (publication date) through Apr 14, 2026

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Diabetes. Apr 15, 2026; 17(4): 116349
Published online Apr 15, 2026. doi: 10.4239/wjd.v17.i4.116349

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Figure 1 Inclusion and exclusion of literature.

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Figure 2 Association between type 2 diabetes mellitus and overall fracture incidence. A: Forest plot of type 2 diabetes mellitus and the overall fracture incidence rate; B: Funnel plot of type 2 diabetes mellitus and overall fracture incidence. CI: Confidence interval.

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Figure 3 Association between type 2 diabetes mellitus and incidence of hip fractures. A: Forest plot illustrating the association between type 2 diabetes mellitus (T2DM) mellitus and hip; B: Sensitivity analysis of T2DM and hip fracture incidence; C: Forest plot of T2DM and hip fracture incidence after heterogeneity literature exclusion. CI: Confidence interval.

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Figure 4 Forest plot. A: Association between type 2 diabetes mellitus (T2DM) and the incidence of nonvertebral fractures; B: T2DM and ankle fracture incidence; C: Association between T2DM and incidence of upper arm fractures; D: T2DM and vertebral fractures; E: T2DM and foot fractures; F: T2DM and humeral fractures. CI: Confidence interval.

Citation: Zou WH, Zhou ZY, Feng YQ, Wang RT, Jiang JJ, Zhang RZ, Li JW. Umbrella review protocol type 2 diabetes mellitus and fracture risk. World J Diabetes 2026; 17(4): 116349
URL: https://www.wjgnet.com/1948-9358/full/v17/i4/116349.htm
DOI: https://dx.doi.org/10.4239/wjd.v17.i4.116349