Correlation between key indicators of continuous glucose monitoring and the risk of diabetic foot

Figure 1 Grading of diabetic foot patients (according to the Wagner grading system).

Figure 2 Restricted cubic spline model demonstrating the linear relationship of mean blood glucose, glycemia risk index, time above range level 1, time above range level 2, and time in range with the risk of diabetic foot. A: Mean blood glucose; B: Glycemia risk index; C: Time above range (TAR) level 1; D: TAR level 2; E: Time in range. MBG: Mean blood glucose; GRI: Glycemia risk index; TAR: Time above range; TIR: Time in range.

Figure 3 Receiver-operating characteristic analysis for identification of patients with the risk of diabetic foot. ROC: Receiver operating characteristic; TIR: Time in range; GRI: Glycemia risk index; MBG: Mean blood glucose; TAR: Time above range; HbA1c: Hemoglobin A1c.

Figure 4 Logistic regression analysis of the proportion of continuous glucose monitoring metrics meeting the standards and their influencing factors. A: The attainment of time in range > 70%; B: The attainment of time above range (TAR) level 1 < 25%; C: The attainment of TAR level 2 < 5%. ¹Adjusted for sex, age, body mass index (BMI), duration of diabetes, duration of diabetic foot, diabetic peripheral neuropathy, white blood cell (WBC), fasting plasma glucose (FPG), hemoglobin A1c (HbA1c), Wagner grade, antidiabetic drugs. ²Adjusted for sex, age, BMI, duration of diabetes, duration of diabetic foot, WBC, FPG, HbA1c, antidiabetic drugs. TAR: Time above range; TIR: Time in range. WBC: White blood cell; HbA1c: Hemoglobin A1c; BMI: Body mass index; FPG: Fasting plasma glucose.