©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jul 10, 2015; 6(7): 927-935
Published online Jul 10, 2015. doi: 10.4239/wjd.v6.i7.927
Published online Jul 10, 2015. doi: 10.4239/wjd.v6.i7.927
Relationship between diabetes and periodontal infection
Fernando Llambés, Department of Stomatology, Dentistry University of Valencia, 46010 Valencia, Spain
Santiago Arias-Herrera, Section of Graduate Periodontology-Faculty of Odontology, Complutense University, 28040 Madrid, Spain
Raúl Caffesse, Complutense University, 28040 Madrid, Spain
Author contributions: Llambés F, Arias-Herrera S and Caffesse R contributed equally to this work; Llambés F designed the research; Llambés F, Arias-Herrera S and Caffesse R performed the research; Llambés F, Arias-Herrera S and Caffesse R contributed new reagents/analytic tools; Llambés F, Arias-Herrera S and Caffesse R analyzed the data; Llambés F, Arias-Herrera S and Caffesse R wrote the paper.
Conflict-of-interest statement: The authors declare that they have no conflict of interests.
Correspondence to: Fernando Llambés, DDS, PhD, Department of Stomatology, Dentistry University of Valencia, la Pechina 51, esc2, pta3, 46010 Valencia, Spain. fernando.llambes@gmail.com
Telephone: +34-96-3518437 Fax: +34-96-3106744
Received: October 21, 2014
Peer-review started: October 21, 2014
First decision: November 14, 2014
Revised: February 25, 2015
Accepted: March 18, 2015
Article in press: March 20, 2015
Published online: July 10, 2015
Processing time: 261 Days and 21.7 Hours
Peer-review started: October 21, 2014
First decision: November 14, 2014
Revised: February 25, 2015
Accepted: March 18, 2015
Article in press: March 20, 2015
Published online: July 10, 2015
Processing time: 261 Days and 21.7 Hours
Core Tip
Core tip: Longitudinal studies have demonstrated a two-way relationship between diabetes and periodontitis, with more severe periodontal tissue destruction in diabetic patients and poorer glycemic control in diabetic subjects with periodontal disease. Periodontal treatment can be successful in diabetic patients, but more recurrence of periodontal disease can be expected in non well controlled diabetic individuals. However, effects of periodontitis and its treatment on diabetes metabolic control are not clearly defined and results of the studies remain controversial. Recommendations for future investigations are included in this review.