©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Mar 15, 2015; 6(2): 352-357
Published online Mar 15, 2015. doi: 10.4239/wjd.v6.i2.352
Published online Mar 15, 2015. doi: 10.4239/wjd.v6.i2.352
Statin use and risk of diabetes mellitus
Bharti Chogtu, KL Bairy, Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, Karnataka 576104, India
Rahul Magazine, Department of Pulmonary Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka 576104, India
Author contributions: Chogtu B performed the literature search and wrote the initial draft of the paper; Magazine R contributed to writing of paper; Bairy KL has given the final suggestions and editing.
Conflict-of-interest: All authors declare that there is no conflict of interest.
Correspondence to: Dr. Bharti Chogtu, Associate Professor, Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, Karnataka 576104, India. bhartimagazine@gmail.com
Telephone: +91-820-2922365 Fax: +91-820-2922083
Received: August 27, 2014
Peer-review started: August 28, 2014
First decision: November 19, 2014
Revised: November 28, 2014
Accepted: December 18, 2014
Article in press: December 19, 2014
Published online: March 15, 2015
Processing time: 204 Days and 3 Hours
Peer-review started: August 28, 2014
First decision: November 19, 2014
Revised: November 28, 2014
Accepted: December 18, 2014
Article in press: December 19, 2014
Published online: March 15, 2015
Processing time: 204 Days and 3 Hours
Core Tip
Core tip: The use of statins in diabetics has long term benefits in terms of decreasing morbidity and mortality. Recent studies have shown that statins increase the incidence of new onset diabetes. The issue became debatable after Food and Drug Administration released changes to statin safety that they increase glycosylated haemoglobin and blood glucose levels. At the same time statins are beneficial in preventing cardiovascular events. Most of the investigators are of the opinion that the risk of diabetes with statins can be outweighed by the long term benefits in preventing complications. In patients with high risk of diabetes, statins should be cautiously used.