©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Mar 15, 2015; 6(2): 338-344
Published online Mar 15, 2015. doi: 10.4239/wjd.v6.i2.338
Published online Mar 15, 2015. doi: 10.4239/wjd.v6.i2.338
Effects of maternal diabetes on trophoblast cells
Marlúcia Bastos Aires, Anne Carolline Veríssimo dos Santos, Department of Morphology, Federal University of Sergipe, São Cristóvão 49100-000, Sergipe, Brazil
Author contributions: Aires MB wrote the manuscript; Santos ACV generated the figures.
Conflict-of-interest: The authors declare that they have no conflict of interest.
Correspondence to: Marlúcia Bastos Aires, PhD, Department of Morphology, Federal University of Sergipe, Av. Marechal Rondon s/n Cidade Universitária Professor José Aloísio de Campos, São Cristóvão 49100-000, Sergipe, Brazil. marlucia_aires@yahoo.com.br
Telephone: +55-79-91298405
Received: August 14, 2014
Peer-review started: August 14, 2014
First decision: November 3, 2014
Revised: December 15, 2014
Accepted: December 29, 2014
Article in press: December 31, 2014
Published online: March 15, 2015
Processing time: 217 Days and 15.3 Hours
Peer-review started: August 14, 2014
First decision: November 3, 2014
Revised: December 15, 2014
Accepted: December 29, 2014
Article in press: December 31, 2014
Published online: March 15, 2015
Processing time: 217 Days and 15.3 Hours
Core Tip
Core tip: This review article focuses on current knowledge about the effects of diabetes on trophoblast function such as proliferation, apoptosis and cell cycle control during placental development in human and rodent animal models. It also briefly discusses some placental pathological findings as a consequence of altered metabolic environment during diabetes.