©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Feb 15, 2015; 6(1): 167-174
Published online Feb 15, 2015. doi: 10.4239/wjd.v6.i1.167
Published online Feb 15, 2015. doi: 10.4239/wjd.v6.i1.167
Rare complications of pediatric diabetic ketoacidosis
Shara R Bialo, Sungeeta Agrawal, Charlotte M Boney, Jose Bernardo Quintos, Division of Pediatric Endocrinology of Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI 02903, United States
Author contributions: All the authors solely contributed to this paper.
Conflict-of-interest: None of the authors have potential, perceived, or real conflict of interest to disclose.
Correspondence to: Jose Bernardo Quintos, MD, Division of Pediatric Endocrinology of Rhode Island Hospital, Warren Alpert Medical School of Brown University, 593 Eddy Street, MPSII, Providence, RI 02903, United States. jose_bernardo_quintos@brown.edu
Telephone: +1-401-4445504 Fax: +1-401-4442534
Received: August 29, 2014
Peer-review started: August 30, 2014
Revised: October 31, 2014
Accepted: December 16, 2014
Article in press: December 17, 2014
Published online: February 15, 2015
Processing time: 155 Days and 10.8 Hours
Peer-review started: August 30, 2014
Revised: October 31, 2014
Accepted: December 16, 2014
Article in press: December 17, 2014
Published online: February 15, 2015
Processing time: 155 Days and 10.8 Hours
Core Tip
Core tip: Diabetic ketoacidosis is highly prevalent in pediatric patients with both newly diagnosed and established type 1 diabetes. The most common rare complication is cerebral edema, which is the leading cause of death in youth with diabetes. However, several other complications involving multiple systems have been described and can cause significant morbidity in cases of pediatric diabetic ketoacidosis, thus warranting awareness and targeted monitoring.