BPG is committed to discovery and dissemination of knowledge
Home / Archive / Volume 17, Issue 8
  • This Article
Peer-Review Report of This Article
CrossCheck and Google Search of This Article
Academic Rules and Norms of This Article
Citation of this article
Corresponding Author of This Article
Research Domain of This Article
Article-Type of This Article
Open-Access Policy of This Article
Times Cited Counts in Google of This Article
Journal Information of This Article
Publication Name
World Journal of Diabetes
ISSN
1948-9358
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Editorial
Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Diabetes. Aug 15, 2026; 17(8): 115342
Published online Aug 15, 2026. doi: 10.4239/wjd.115342
RRM2 and the ferroptosis-oxidative stress axis in diabetic kidney disease: Emerging insights from recent evidence
Tong-Jian Zhao, Nian-Zhe Sun
Tong-Jian Zhao, Joslin Diabetes Center, Harvard Medical School, Boston, MA 02115, United States
Nian-Zhe Sun, National Clinical Research Center of Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
Nian-Zhe Sun, Department of Orthopedics, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
Author contributions: Zhao TJ wrote the first draft, developed the main ideas, and led revisions; Sun NZ provided critical feedback, improved the structure, and added key examples.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Nian-Zhe Sun, MD, National Clinical Research Center of Geriatric Disorders, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha 410008, Hunan Province, China. sunnzh201921@sina.com
Received: October 15, 2025
Revised: December 11, 2025
Accepted: December 29, 2025
Published online: August 15, 2026
Processing time: 295 Days and 2.4 Hours
Core Tip

Core Tip: Recent evidence identifies RRM2 as a regulator of ferroptosis in diabetic kidney disease (DKD) through activation of the PI3K/Akt/Nrf2 pathway. This editorial highlights the significance of this finding, critically evaluates its limitations, and discusses its potential as a biomarker and therapeutic target in DKD.
Write to the Help Desk
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.