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World J Diabetes. Nov 15, 2026; 17(11): 123436
Published online Nov 15, 2026. doi: 10.4239/wjd.123436
Published online Nov 15, 2026. doi: 10.4239/wjd.123436
Development and validation of a nomogram for predicting comorbid anxiety and depression in patients with gestational diabetes mellitus
Chang-Wei Zhu, Department of Obstetrics and Gynecology, Affiliated Hospital of Jiangnan University, Wuxi 214000, Jiangsu Province, China
Ling Wang, Department One of Obstetrics and Gynecology, Suzhou Hospital of Traditional Chinese Medicine, Suzhou 215000, Jiangsu Province, China
Author contributions: Zhu CW designed the study, involved in the data collection and writing of this article; Zhu CW and Wang L analyzed the data; All authors have read and approved the final manuscript.
AI contribution statement: The authors declare that no artificial intelligence tools were used in manuscript drafting, statistical analysis, result interpretation or conclusion formulation. All content was independently completed and reviewed by the authors, who take full academic responsibility for the integrity and originality of this manuscript.
Institutional review board statement: All procedures in this study strictly followed the ethical principles of the Declaration of Helsinki. The research protocol was reviewed and approved by the Ethics Committee of the Affiliated Hospital of Jiangnan University (No. LS2024013).
Informed consent statement: Prior to participation in this study, all research participants signed a written informed consent form to confirm their willingness to participate.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: The raw dataset and statistical analysis code supporting the findings of this study are available from the corresponding author upon reasonable formal request. All participant data were fully anonymized to protect patient privacy.
Corresponding author: Chang-Wei Zhu, MD, Deputy Director, Department of Obstetrics and Gynecology, Affiliated Hospital of Jiangnan University, No. 1000 Hefeng Road, Binhu District, Wuxi 214000, Jiangsu Province, China. gh5870506@163.com
Received: June 12, 2026
Revised: July 13, 2026
Accepted: September 23, 2026
Published online: November 15, 2026
Processing time: 145 Days and 10.8 Hours
Revised: July 13, 2026
Accepted: September 23, 2026
Published online: November 15, 2026
Processing time: 145 Days and 10.8 Hours
Core Tip
Core Tip: This study explored the factors associated with combined anxiety and depression in pregnant women with gestational diabetes mellitus (GDM) and constructed a targeted risk prediction nomogram. The results emphasized that older maternal age, prior miscarriage, lower educational attainment, and limited social support were key contributors to psychological comorbidities. The prediction model showed good diagnostic performance. Therefore, it may serve as a practical tool for early detection and timely intervention of emotional disorders in GDM patients. Future research should aim for external validation and further refinement of this model to enhance its accuracy and clinical applicability.