©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Mar 15, 2025; 16(3): 103032
Published online Mar 15, 2025. doi: 10.4239/wjd.v16.i3.103032
Published online Mar 15, 2025. doi: 10.4239/wjd.v16.i3.103032
Electroacupuncture relieves type 2 diabetes by regulating gut microbiome
Ya-Jing Yang, Hao-Ran Tian, Feng-Xia Liang, Department of Acupuncture and Moxibustion, Hubei University of Chinese Medicine, Wuhan 430065, Hubei Province, China
Xu-Chang Zhou, Department of Rehabilitation Medicine, The First Affiliated Hospital of Xiamen University, Xiamen 361003, Fujian Province, China
Co-first authors: Ya-Jing Yang and Xu-Chang Zhou.
Author contributions: Yang YJ and Zhou XC contribute equally to this study as co-first authors; Liang FX and Zhou XC designed and coordinated the article; Yang YJ, Zhou XC, and Tian HR wrote the manuscript; All authors approved the final version of the article.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Corresponding author: Feng-Xia Liang, Chief Physician, PhD, Professor, Department of Acupuncture and Moxibustion, Hubei University of Chinese Medicine, No. 169 Donghu Road, Shuiguohu Street, Wuchang District, Wuhan 430071, Hubei Province, China.
Received: November 6, 2024
Revised: December 30, 2024
Accepted: January 8, 2025
Published online: March 15, 2025
Processing time: 76 Days and 21.4 Hours
Revised: December 30, 2024
Accepted: January 8, 2025
Published online: March 15, 2025
Processing time: 76 Days and 21.4 Hours
Core Tip
Core Tip: The gut microbiome may indirectly affect the course of diabetes by influencing microbial metabolites, the intestinal barrier function, and the intestinal immune system. Recent studies have reported that electroacupuncture (EA) can rectify the imbalance of the gut microbiome. By reviewing the literature related to traditional Chinese medicine and modern microbiome, this paper discussed the mechanism of action of how EA improves glucose metabolism and treats type 2 diabetes mellitus from the perspective of the gut microbiome.