Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Sep 15, 2024; 15(9): 1903-1915
Published online Sep 15, 2024. doi: 10.4239/wjd.v15.i9.1903
Non-linear relationship between age and subfoveal choroidal thickness in Chinese patients with proliferative diabetic retinopathy
Chun-Yan Lei, Jiang-Ying Xie, Qi-Bo Ran, Mei-Xia Zhang
Chun-Yan Lei, Qi-Bo Ran, Mei-Xia Zhang, Department of Ophthalmology and Research Laboratory of Macular Disease, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Jiang-Ying Xie, Sichuan University Operating Room, Department of Anesthesiology, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu 610041, Sichuan Province, China
Co-first authors: Chun-Yan Lei and Jiang-Ying Xie.
Author contributions: Lei CY and Zhang MX designed the research study; Lei CY and Xie JY performed the research; Ran QB contributed analytic tools; Lei CY and Xie JY analyzed the data and wrote the manuscript; and all authors have read and approved the final manuscript.
Supported by the 1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan University, No. ZYJC21025.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of the Ethical Committee of the West China Hospital of Sichuan University [Approval No. 2020(834)].
Informed consent statement: The data were anonymous and informed consent was waived by the approving Institutional Review Board because of the retrospective nature of the study.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: Data will be made available on reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mei-Xia Zhang, MD, Chief Physician, Full Professor, Surgeon, Department of Ophthalmology and Research Laboratory of Macular Disease, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Wuhou District, Chengdu 610041, Sichuan Province, China. zhangmeixia@scu.edu.cn
Received: May 7, 2024
Revised: June 11, 2024
Accepted: July 16, 2024
Published online: September 15, 2024
Processing time: 112 Days and 3.7 Hours
Core Tip

Core Tip: In the present study, the average subfoveal choroidal thickness (SFCT) of patients with proliferative diabetic retinopathy (PDR) was inversely correlated with age, and a reduction of 1.68 μm in SFCT per year was observed. Additionally, there was a progressively increasing trend in SFCT of 2.00 μm per year before the age of 54 years and a negative correlation of 4.89 μm per year after the age of 54 years; therefore, age around 54 years might be an important turning point. This is the first study to reveal a relationship between age and SFCT in patients with PDR.