©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Feb 15, 2024; 15(2): 209-219
Published online Feb 15, 2024. doi: 10.4239/wjd.v15.i2.209
Published online Feb 15, 2024. doi: 10.4239/wjd.v15.i2.209
Vitamin D, selenium, and antidiabetic drugs in the treatment of type 2 diabetes mellitus with Hashimoto's thyroiditis
Fen Feng, School of Pharmacy, Shaoyang University, Shaoyang 422099, Hunan Province, China
Bin Zhou, Ci-La Zhou, Ping Huang, Gang Wang, Kuang Yao, Department of Endocrinology, The Central Hospital of Shaoyang, Shaoyang 422099, Hunan Province, China
Author contributions: Feng F and Zhou B jointly researched, wrote, and revised the paper; Zhou CL, Huang P, Wang G, and Yao K participated in the analysis and provided clinical advice.
Supported by Science and Technology Plan Project of Shaoyang City , No. 2022GX4139 .
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of The Central Hospital of Shaoyang.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Corresponding author: Bin Zhou, MM, Chief Physician, Department of Endocrinology, The Central Hospital of Shaoyang, No. 36 Qianyuan Lane, Hongqi Road, Daxiang District, Shaoyang 422099, Hunan Province, China. zhoubin790921@163.com
Received: November 22, 2023
Peer-review started: November 22, 2023
First decision: December 8, 2023
Revised: December 16, 2023
Accepted: January 16, 2024
Article in press: January 16, 2024
Published online: February 15, 2024
Processing time: 74 Days and 1.8 Hours
Peer-review started: November 22, 2023
First decision: December 8, 2023
Revised: December 16, 2023
Accepted: January 16, 2024
Article in press: January 16, 2024
Published online: February 15, 2024
Processing time: 74 Days and 1.8 Hours
Core Tip
Core Tip: Selenium yeast and active vitamin D can reduce thyroid-related antibodies in type-2 diabetes mellitus (T2DM) and Hashimoto's thyroiditis (HT) and improve thyroid function. Hypoglycemia drugs can lower blood sugar levels in patients and promote blood sugar stability. While most patients with T2DM and HT are currently treated with a single symptomatic drug, the effects are unsatisfactory. In this study, the combination of vitamin D and selenium yeast added to hypoglycemic agents to treat T2DM patients with HT showed a remarkable therapeutic effect.