Randomized Controlled Trial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Dec 15, 2024; 15(12): 2311-2321
Published online Dec 15, 2024. doi: 10.4239/wjd.v15.i12.2311
Effect of three-week exercise program on muscle strength and joint mobility in patients with diabetic polyneuropathy: Randomized controlled trial
Snježana Novaković-Bursać, Goran Talić, Nataša Tomić, Ranko Škrbić, Ivan Soldatovic
Snježana Novaković-Bursać, Goran Talić, Nataša Tomić, Management, Institute for Physical Medicine, Rehabilitation and Orthopedic Surgery “Dr Miroslav Zotović” Banja Luka, Banja Luka 78000, Republika Srpska, Bosnia and Herzegovina
Ranko Škrbić, Centre for Biomedical Research, Faculty of Medicine, University of Banja Luka, Banja Luka 78000, Republika Srpska, Bosnia and Herzegovina
Ivan Soldatovic, Institute of Medical Statistics and Informatic, Faculty of Medicine, University of Belgrade, Belgrade 11000, Serbia
Co-corresponding authors: Snježana Novaković-Bursać and Ivan Soldatovic.
Author contributions: Novaković-Bursać S was responsible for designing and performing the study; Soldatovic I and Škrbic R were responsible for data analysis; Novaković-Bursać S, Talić G, Tomić N, Škrbić R and Soldatovic I were responsible for discussing and interpreting the results and writing the final version to be published; All authors read and approved the final manuscript.
Institutional review board statement: The clinical trial was approved by the Ethics Committees of the Institute, protocol number: No. 116-31-3090-1/20.
Clinical trial registration statement: The trial is registered in ANZCRT with registration number: No. ACTRN12624000844549.
Informed consent statement: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: All the data and materials that are required to reproduce these findings can be shared by contacting the corresponding author.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Snježana Novaković-Bursać, MD, MSc, Doctor, Medical Director, Management, Institute for Physical Medicine, Rehabilitation and Orthopedic Surgery “Dr Miroslav Zotović” Banja Luka, Slatinska 11, Banja Luka 78000, Republika Srpska, Bosnia and Herzegovina. snjezana.nb@ms.zotovicbl.org
Received: May 30, 2024
Revised: August 28, 2024
Accepted: October 9, 2024
Published online: December 15, 2024
Processing time: 171 Days and 17 Hours
Core Tip

Core Tip: Improvement in biomechanical parameters, while enhancing mobility and overall patient condition, has the potential to reduce the risk of developing diabetic ulcers in patients with diabetic neuropathy. A combined and supervised exercise program lasting 15 therapy days, consisting of stretching, strength, functional and walking exercises, can improve the mobility in the ankle, subtalar and first metatarsophalangeal joint, as well as the strength of the foot and lower leg muscles in patients with diabetic peripheral neuropathy. The effects achieved by this treatment can last up to 6 months after the intervention.