©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Dec 15, 2021; 12(12): 2036-2049
Published online Dec 15, 2021. doi: 10.4239/wjd.v12.i12.2036
Published online Dec 15, 2021. doi: 10.4239/wjd.v12.i12.2036
Hypoglycemia in diabetes: An update on pathophysiology, treatment, and prevention
Afif Nakhleh, Naim Shehadeh, Institute of Endocrinology, Diabetes and Metabolism, Rambam Health Care Campus, Haifa 3109601, Israel
Author contributions: Nakhleh A drafted the manuscript; Both authors edited and approved the final version of the manuscript.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest.
Corresponding author: Afif Nakhleh, MD, Doctor, Institute of Endocrinology, Diabetes and Metabolism, Rambam Health Care Campus, HaAliya HaShniya Street 8, Haifa 3109601, Israel. anakhleh@gmail.com
Received: September 3, 2021
Peer-review started: September 3, 2021
First decision: October 3, 2021
Revised: October 16, 2021
Accepted: December 7, 2021
Article in press: December 7, 2021
Published online: December 15, 2021
Processing time: 104 Days and 3.6 Hours
Peer-review started: September 3, 2021
First decision: October 3, 2021
Revised: October 16, 2021
Accepted: December 7, 2021
Article in press: December 7, 2021
Published online: December 15, 2021
Processing time: 104 Days and 3.6 Hours
Core Tip
Core Tip: Hypoglycemia in diabetes is associated with increased morbidity and constitutes a barrier to glycemic control. Great effort must be invested in patient education on hypoglycemia prevention and management. Herein we present the recent data on the treatment and prevention of hypoglycemia in diabetes, with a focus on the benefits of treatment adjustment and the role of continuous glucose monitoring.