Different nutrient compositions in diet and taking hypoglycemic drugs can modulate gut microbial flora

doi:10.4239/wjd.v13.i9.799

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World Journal of Diabetes

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Letter to the Editor

World J Diabetes. Sep 15, 2022; 13(9): 799-801
Published online Sep 15, 2022. doi: 10.4239/wjd.v13.i9.799

Different nutrient compositions in diet and taking hypoglycemic drugs can modulate gut microbial flora

Zi-Jun Lin, Qiong-Wen Zhang, Xiao-Lan Yu, Bo Zhou, Chang-Wei Liu, Lian-Ping He

Zi-Jun Lin, Qiong-Wen Zhang, Xiao-Lan Yu, Bo Zhou, Lian-Ping He, School of Medicine, Taizhou University, Jiaojiang 318000, Zhejiang Province, China

Chang-Wei Liu, Children’s Hospital of Nanjing Medical University, Nanjing 210008, Jiangsu Province, China

Author contributions: He LP and Liu CW contributed to the conception of research; Zhang QW, Lin ZJ and Zhou B wrote the manuscript; Zhang QW, Lin ZJ and Yu XL contributed to the revision of the manuscript.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Corresponding author: Chang-Wei Liu, MM, Doctor, Children’s Hospital of Nanjing Medical University, No. 72 Guangzhou Road, Nanjing 210008, Jiangsu Province, China. liuchangwei07@163.com

Received: May 24, 2022
Peer-review started: May 24, 2022
First decision: July 14, 2022
Revised: July 22, 2022
Accepted: August 16, 2022
Article in press: August 16, 2022
Published online: September 15, 2022
Processing time: 108 Days and 7.9 Hours

Abstract

The diet structure of diabetic patients is different from that of normal people. Diabetic patients also need to take hypoglycemic drugs to regulate blood sugar. Both dieting and drugs affect the gut microbiota of diabetic patients. In this letter, we discuss that different dietary patterns and the use of hypoglycemic agents may have an impact on changes in gut microbiota in diabetic patients.

Keywords: Diabetic patients; Gut microbiota; Hypoglycemic drugs

Core Tip: Changes in diet can lead to changes in the composition of gut microbiota in diabetic patients. On the other hand, taking hypoglycemic drugs can also change the gut microbiota. Therefore, it is necessary to consider the dietary structure and the use of hypoglycemic drugs in the study of changes in the intestinal flora of patients with diabetes.