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For: Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, Richards DR, McDonald-Smith GP, Gao H, Hennessy L, Finnerty CC, López CM, Honari S, Moore EE, Minei JP, Cuschieri J, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Jeschke MG, Klein MB, Gamelli RL, Gibran NS, Brownstein BH, Miller-Graziano C, Calvano SE, Mason PH, Cobb JP, Rahme LG, Lowry SF, Maier RV, Moldawer LL, Herndon DN, Davis RW, Xiao W, Tompkins RG; Inflammation and Host Response to Injury, Large Scale Collaborative Research Program. Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A 2013;110:3507-12. [PMID: 23401516 DOI: 10.1073/pnas.1222878110] [Citation(s) in RCA: 2275] [Impact Index Per Article: 189.6] [Reference Citation Analysis] [What about the content of this article? (0)] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 02/07/2023]  Open
Number Cited by Other Article(s)
1
Zhu J, Zhou J, Tao C, Xia G, Liu B, Zheng X, Li X, Zhang Z. Identification of early prognostic biomarkers in Severe Fever with Thrombocytopenia Syndrome using machine learning algorithms. Ann Med 2025;57:2451184. [PMID: 39803909 PMCID: PMC11730770 DOI: 10.1080/07853890.2025.2451184] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 07/29/2024] [Revised: 12/14/2024] [Accepted: 12/16/2024] [Indexed: 01/16/2025]  Open
2
Zhu C, Huang K, Li T, Li Y, Jin Y, Li R, Zhu Z, Yang S, Xia L, Fang B. Manganese dioxide coupled metal-organic framework as mitophagy regulator alleviates periodontitis through SIRT1-FOXO3-BNIP3 signaling axis. Biomaterials 2025;319:123179. [PMID: 39983516 DOI: 10.1016/j.biomaterials.2025.123179] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/01/2024] [Revised: 01/27/2025] [Accepted: 02/08/2025] [Indexed: 02/23/2025]
3
Ton Nu QC, Deka G, Park PH. CD8+ T cell-based immunotherapy: Promising frontier in human diseases. Biochem Pharmacol 2025;237:116909. [PMID: 40179991 DOI: 10.1016/j.bcp.2025.116909] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/10/2024] [Revised: 02/28/2025] [Accepted: 03/26/2025] [Indexed: 04/05/2025]
4
Klima S, Hurrell T, Goolam M, Gouws C, Engelbrecht AM, Kaur M, van den Bout I. A new dawn: Vitalising translational oncology research in Africa with the help of advanced cell culture models. Transl Oncol 2025;56:102391. [PMID: 40228390 PMCID: PMC12017847 DOI: 10.1016/j.tranon.2025.102391] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/27/2024] [Revised: 03/12/2025] [Accepted: 04/07/2025] [Indexed: 04/16/2025]  Open
5
Burtscher J, Motl RW, Berek K, Ehrenreich H, Kopp M, Hohenauer E. Hypoxia in multiple sclerosis. Redox Biol 2025;83:103666. [PMID: 40347693 DOI: 10.1016/j.redox.2025.103666] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 04/14/2025] [Revised: 05/05/2025] [Accepted: 05/05/2025] [Indexed: 05/14/2025]  Open
6
Smith KWY, Fung SL, Wu HF, Chiesa I, Vozzi G, De Maria C, Gottardi R. Developing an in vitro osteochondral micro-physiological system for modeling cartilage-bone crosstalk in arthritis. Front Immunol 2025;16:1495613. [PMID: 40491903 PMCID: PMC12146386 DOI: 10.3389/fimmu.2025.1495613] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/12/2024] [Accepted: 04/10/2025] [Indexed: 06/11/2025]  Open
7
Sengupta A, Schmid S, Grangier N, Dorn A, Hebestreit M, Hugi A, Žajdlíková K, Herbst A, Losada-Oliva P, Ortolf-Wahl H, Krebs P, Stucki JD, van der Velpen V, Perez-Gil J, Krebs T, Hobi N, Guenat OT. A next-generation system for smoke inhalation integrated with a breathing lung-on-chip to model human lung responses to cigarette exposure. Sci Rep 2025;15:18181. [PMID: 40414911 DOI: 10.1038/s41598-025-00438-z] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/07/2024] [Accepted: 04/28/2025] [Indexed: 05/27/2025]  Open
8
Hans A, Salil, Sawant P, Ajgaonkar B, Jain R, Dandekar P. Cryopreservation of human lung adenocarcinoma spheroids using MMC based cryomixtures. JOURNAL OF BIOMATERIALS SCIENCE. POLYMER EDITION 2025:1-22. [PMID: 40372794 DOI: 10.1080/09205063.2025.2502096] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 02/06/2025] [Accepted: 04/04/2025] [Indexed: 05/17/2025]
9
Zhang X, Zhao M, Deng P, Liu H, Li H, Zhang X, Wang D, Qin J. Modeling Idiopathic Inflammatory Myopathy in the Bioinspired Muscle Tissue on Chip. Adv Healthc Mater 2025:e2405111. [PMID: 40357815 DOI: 10.1002/adhm.202405111] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/17/2024] [Revised: 04/21/2025] [Indexed: 05/15/2025]
10
Noga M, Jurowski K. Reexamining the acute toxicity of chloropicrin: Comprehensive estimation using in silico methods. Toxicol In Vitro 2025;105:106033. [PMID: 40020763 DOI: 10.1016/j.tiv.2025.106033] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/31/2024] [Revised: 01/27/2025] [Accepted: 02/15/2025] [Indexed: 03/03/2025]
11
Keramati F, Leijte GP, Bruse N, Grondman I, Habibi E, Ruiz-Moreno C, Megchelenbrink W, Peters van Ton AM, Heesakkers H, Bremmers ME, van Grinsven E, Tesselaar K, van Staveren S, van der Velden WJ, Preijers FW, Te Pas B, van de Loop R, Gerretsen J, Netea MG, Stunnenberg HG, Pickkers P, Kox M. Systemic inflammation impairs myelopoiesis and interferon type I responses in humans. Nat Immunol 2025;26:737-747. [PMID: 40251340 PMCID: PMC12043512 DOI: 10.1038/s41590-025-02136-4] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/15/2023] [Accepted: 03/17/2025] [Indexed: 04/20/2025]
12
Qualls KA, Kadakia FK, Serafin EK, Lückemeyer DDN, Davidson S, Strong JA, Zhang JM. mRNA Expression of Mineralocorticoid and Glucocorticoid Receptors in Human and Mouse Sensory Neurons of the Dorsal Root Ganglia. Anesth Analg 2025;140:1216-1226. [PMID: 39808573 PMCID: PMC11919799 DOI: 10.1213/ane.0000000000007133] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/16/2025]
13
Levinson S, Pulli B, Heit JJ. Neuroinflammation and acute ischemic stroke: impact on translational research and clinical care. Front Surg 2025;12:1501359. [PMID: 40356948 PMCID: PMC12066521 DOI: 10.3389/fsurg.2025.1501359] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/24/2024] [Accepted: 04/07/2025] [Indexed: 05/15/2025]  Open
14
Jeong PS, Yang HJ, Park YH, Jin YB, Song BS, Hong JJ, Lee SH, Lee JH, Lim KS, Jeong KJ, Kang P, Lee HY, Son HC, Kim HN, Ha SM, Hwang EH, Cha JJ, Jung Y, Choi SA, Lee S, Lee SR, Lee SC, Kang KS, Hur CG, Jung YW, Koo DB, Choo YK, Kim JM, Sim BW, Kim SU. JAK3-deficient mini-pigs exhibit impaired lymphoid organogenesis, intestinal structure, and leukocyte/cytokine production. J Adv Res 2025:S2090-1232(25)00280-2. [PMID: 40280544 DOI: 10.1016/j.jare.2025.04.036] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/07/2024] [Revised: 01/09/2025] [Accepted: 04/21/2025] [Indexed: 04/29/2025]  Open
15
Sharif E, Mobasheri T, Mohit E. Bioengineered ClearColi™-derived outer membrane vesicles displaying CT26 neoepitopes as potent vaccine adjuvants against colon carcinoma in a preventive mouse model. Vaccine 2025;53:127088. [PMID: 40209628 DOI: 10.1016/j.vaccine.2025.127088] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/26/2024] [Revised: 03/17/2025] [Accepted: 03/29/2025] [Indexed: 04/12/2025]
16
Wang H, Ayala A, Aziz M, Billiar TR, Deutschman CS, Jeyaseelan S, Tang D, Wang P. Value of animal sepsis research in navigating the translational labyrinth. Front Immunol 2025;16:1593342. [PMID: 40303397 PMCID: PMC12037402 DOI: 10.3389/fimmu.2025.1593342] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 03/13/2025] [Accepted: 04/04/2025] [Indexed: 05/02/2025]  Open
17
Brunmaier LAE, Ozdemir T, Walker TW. Angiogenesis: Biological Mechanisms and In Vitro Models. Ann Biomed Eng 2025:10.1007/s10439-025-03721-2. [PMID: 40210793 DOI: 10.1007/s10439-025-03721-2] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/10/2025] [Accepted: 03/25/2025] [Indexed: 04/12/2025]
18
Kim SY, van de Wetering M, Clevers H, Sanders K. The future of tumor organoids in precision therapy. Trends Cancer 2025:S2405-8033(25)00073-1. [PMID: 40185656 DOI: 10.1016/j.trecan.2025.03.005] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/04/2024] [Revised: 03/07/2025] [Accepted: 03/10/2025] [Indexed: 04/07/2025]
19
Shamul JG, Wang Z, Gong H, Ou W, White AM, Moniz-Garcia DP, Gu S, Clyne AM, Quiñones-Hinojosa A, He X. Meta-analysis of the make-up and properties of in vitro models of the healthy and diseased blood-brain barrier. Nat Biomed Eng 2025;9:566-598. [PMID: 39304761 PMCID: PMC11922799 DOI: 10.1038/s41551-024-01250-2] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/06/2023] [Accepted: 08/08/2024] [Indexed: 09/22/2024]
20
Fakhri Bafghi MS, Khoshnam Rad N, Roostaei G, Nikfar S, Abdollahi M. The reality of modeling irritable bowel syndrome: progress and challenges. Expert Opin Drug Discov 2025;20:433-445. [PMID: 40162721 DOI: 10.1080/17460441.2025.2481264] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/03/2024] [Accepted: 03/14/2025] [Indexed: 04/02/2025]
21
Kunze M, Malfatti F. Towards a Conceptual Framework to Better Understand the Advantages and Limitations of Model Organisms. Eur J Neurosci 2025;61:e70071. [PMID: 40165014 DOI: 10.1111/ejn.70071] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/17/2024] [Revised: 02/20/2025] [Accepted: 03/05/2025] [Indexed: 04/02/2025]
22
SoRelle ED, Luftig MA. Multiple sclerosis and infection: history, EBV, and the search for mechanism. Microbiol Mol Biol Rev 2025;89:e0011923. [PMID: 39817754 PMCID: PMC11948499 DOI: 10.1128/mmbr.00119-23] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/18/2025]  Open
23
Willis ML, Seim R, Herring LE, Mordant AL, Webb TS, Upchurch GR, Sharma AK, Cairns BA, Efron P, Wallet SM, Coleman LG, Maile R. Temporal changes in the protein cargo of extracellular vesicles and resultant immune reprogramming after severe burn injury in humans and mice. BIORXIV : THE PREPRINT SERVER FOR BIOLOGY 2025:2025.03.19.644202. [PMID: 40166336 PMCID: PMC11957110 DOI: 10.1101/2025.03.19.644202] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Indexed: 04/02/2025]
24
Nelson JL, Lambert NC. The when, what, and where of naturally-acquired microchimerism. Semin Immunopathol 2025;47:20. [PMID: 40067465 DOI: 10.1007/s00281-024-01029-2] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/13/2024] [Accepted: 11/14/2024] [Indexed: 05/13/2025]
25
Kühtreiber H, Bormann D, Salek M, Auer L, Haider T, Mildner CS, Lingitz MT, Aigner C, Radtke C, Zimpfer D, Ankersmit HJ, Mildner M. Burn-Related Glycocalyx Derangement and the Emerging Role of MMP8 in Syndecan Shedding. BIOLOGY 2025;14:269. [PMID: 40136525 PMCID: PMC11940132 DOI: 10.3390/biology14030269] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 01/09/2025] [Revised: 02/26/2025] [Accepted: 03/04/2025] [Indexed: 03/27/2025]
26
Cayford J, Atteberry B, Singh-Taylor A, Retter A, Berman BP, Kelly TK. Chromatin changes associated with neutrophil extracellular trap formation in whole blood reflect complex immune signaling. Front Immunol 2025;16:1515430. [PMID: 40103826 PMCID: PMC11914908 DOI: 10.3389/fimmu.2025.1515430] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/22/2024] [Accepted: 02/03/2025] [Indexed: 03/20/2025]  Open
27
Lopes CF, Laurent E, Caul-Futy M, Dubois J, Mialon C, Chojnacki C, Sage E, Boda B, Huang S, Rosa-Calatrava M, Constant S. A Novel In Vitro Primary Human Alveolar Model (AlveolAir™) for H1N1 and SARS-CoV-2 Infection and Antiviral Screening. Microorganisms 2025;13:572. [PMID: 40142465 PMCID: PMC11944821 DOI: 10.3390/microorganisms13030572] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/05/2025] [Revised: 02/20/2025] [Accepted: 02/25/2025] [Indexed: 03/28/2025]  Open
28
Pilalis E, Zisis D, Andrinopoulou C, Karamanidou T, Antonara M, Stavropoulos TG, Chatziioannou A. Genome-wide functional annotation of variants: a systematic review of state-of-the-art tools, techniques and resources. Front Pharmacol 2025;16:1474026. [PMID: 40098614 PMCID: PMC11911558 DOI: 10.3389/fphar.2025.1474026] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/31/2024] [Accepted: 02/03/2025] [Indexed: 03/19/2025]  Open
29
Sahoo SS, Khiami M, Wlodarski MW. Inducible pluripotent stem cell models to study bone marrow failure and MDS predisposition syndromes. Exp Hematol 2025;143:104669. [PMID: 39491640 DOI: 10.1016/j.exphem.2024.104669] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/02/2024] [Revised: 10/24/2024] [Accepted: 10/26/2024] [Indexed: 11/05/2024]
30
Yang J, Xie YF, Smith R, Ratté S, Prescott SA. Discordance between preclinical and clinical testing of Na V 1.7-selective inhibitors for pain. Pain 2025;166:481-501. [PMID: 39928833 PMCID: PMC11808711 DOI: 10.1097/j.pain.0000000000003425] [Citation(s) in RCA: 3] [Impact Index Per Article: 3.0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/13/2024] [Revised: 07/19/2024] [Accepted: 08/13/2024] [Indexed: 10/26/2024]
31
Mattingly Z, Chetty S. Untangling the Molecular Mechanisms Contributing to Autism Spectrum Disorder Using Stem Cells. Autism Res 2025;18:476-485. [PMID: 39989339 DOI: 10.1002/aur.70005] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/12/2024] [Revised: 02/06/2025] [Accepted: 02/08/2025] [Indexed: 02/25/2025]
32
Bukhari MMM, Khabooshani M, Naqvi SM, McNamara LM. Estrogen deficiency alters vascularization and mineralization dynamics: insight from a novel 3-D humanized and vascularized bone organoid model. Am J Physiol Cell Physiol 2025;328:C743-C756. [PMID: 39819034 DOI: 10.1152/ajpcell.00738.2024] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 10/02/2024] [Revised: 10/24/2024] [Accepted: 01/04/2025] [Indexed: 01/19/2025]
33
Frost MR, Ball BK, Pendyala M, Douglas SR, Brubaker DK, Chan DD. Computational Translation of Mouse Models of Osteoarthritis Predicts Human Disease. BIORXIV : THE PREPRINT SERVER FOR BIOLOGY 2025:2025.02.23.639777. [PMID: 40060529 PMCID: PMC11888325 DOI: 10.1101/2025.02.23.639777] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Indexed: 03/16/2025]
34
Hennessy Garza R, Mahoney JE, Burns M, Quanbeck A. Connecting the bibliographic-directed citation networks of translational research and implementation science. J Clin Transl Sci 2025;9:e64. [PMID: 40201632 PMCID: PMC11975788 DOI: 10.1017/cts.2025.11] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/17/2022] [Revised: 01/14/2025] [Accepted: 01/16/2025] [Indexed: 04/10/2025]  Open
35
Nakagawa K, Yamazaki M, Tanimura H, Sakaguchi N, Kohara M, Sato I, Azuma M, Nishimoto-Kakiuchi A, Kato A, Kitazawa T, Konno R, Sankai T. Development of a novel postoperative adhesion induction model in cynomolgus monkeys with high reliability and reproducibility. Sci Rep 2025;15:7102. [PMID: 40016251 PMCID: PMC11868379 DOI: 10.1038/s41598-025-88022-3] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/30/2024] [Accepted: 01/23/2025] [Indexed: 03/01/2025]  Open
36
An L, Liu Y, Liu Y. Organ-on-a-Chip Applications in Microfluidic Platforms. MICROMACHINES 2025;16:201. [PMID: 40047688 PMCID: PMC11857120 DOI: 10.3390/mi16020201] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Received: 12/23/2024] [Revised: 02/06/2025] [Accepted: 02/08/2025] [Indexed: 03/09/2025]
37
Segal Y, Soltys J, Clarkson BDS, Howe CL, Irani SR, Pittock SJ. Toward curing neurological autoimmune disorders: Biomarkers, immunological mechanisms, and therapeutic targets. Neuron 2025;113:345-379. [PMID: 39809275 DOI: 10.1016/j.neuron.2024.12.006] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/21/2024] [Revised: 10/26/2024] [Accepted: 12/04/2024] [Indexed: 01/16/2025]
38
Cohen SM, Boobis AR, Jacobson-Kram D, Schoeny R, Rosol TJ, Williams GM, Kaminski NE, Eichenbaum GM, Guengerich FP, Nash JF. Mode of action approach supports a lack of carcinogenic potential of six organic UV filters. Crit Rev Toxicol 2025;55:248-284. [PMID: 40208192 DOI: 10.1080/10408444.2025.2462642] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/19/2024] [Revised: 01/06/2025] [Accepted: 01/10/2025] [Indexed: 04/11/2025]
39
Hu Y, Schnabl B, Stärkel P. Origin, Function, and Implications of Intestinal and Hepatic Macrophages in the Pathogenesis of Alcohol-Associated Liver Disease. Cells 2025;14:207. [PMID: 39936998 PMCID: PMC11816606 DOI: 10.3390/cells14030207] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/15/2024] [Revised: 01/12/2025] [Accepted: 01/15/2025] [Indexed: 02/13/2025]  Open
40
Elhaieg A, Farag A, Mandour AS, Hirose M, Elfadadny A, Tanaka R. Murine Models in Oral Research: A Narrative Review of Experimental Approaches and Cardiovascular Implications. BIOLOGY 2025;14:127. [PMID: 40001895 PMCID: PMC11851954 DOI: 10.3390/biology14020127] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Subscribe] [Scholar Register] [Received: 12/23/2024] [Revised: 01/20/2025] [Accepted: 01/24/2025] [Indexed: 02/27/2025]
41
Zhang R, Li G, Zhang Q, Wang Z, Xiang D, Zhang X, Chen J, Hutchins A, Qin D, Su H, Pei D, Li D. c-JUN: a chromatin repressor that limits mesoderm differentiation in human pluripotent stem cells. Nucleic Acids Res 2025;53:gkaf001. [PMID: 39876710 PMCID: PMC11760979 DOI: 10.1093/nar/gkaf001] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/10/2024] [Revised: 12/24/2024] [Accepted: 01/03/2025] [Indexed: 01/30/2025]  Open
42
Mathias FAS, Carvalho MGR, Ruiz JC. Therapeutic Vaccines for Hematological Cancers: A Scoping Review of This Immunotherapeutic Approach as Alternative to the Treatment of These Malignancies. Vaccines (Basel) 2025;13:114. [PMID: 40006660 PMCID: PMC11860334 DOI: 10.3390/vaccines13020114] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/06/2024] [Revised: 01/17/2025] [Accepted: 01/21/2025] [Indexed: 02/27/2025]  Open
43
Schoeberl B, Musante CJ, Ramanujan S. Future Directions for Quantitative Systems Pharmacology. Handb Exp Pharmacol 2025. [PMID: 39812657 DOI: 10.1007/164_2024_737] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/16/2025]
44
Wang B, Hasturk O, Kumarasinghe U, Rudolph S, Staii C, Chen Y, Kaplan DL. Temporary Nanoencapsulation of Human Intestinal Organoids Using Silk Ionomers. Adv Healthc Mater 2025;14:e2403176. [PMID: 39648539 DOI: 10.1002/adhm.202403176] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/24/2024] [Revised: 11/03/2024] [Indexed: 12/10/2024]
45
Yildirim Z, Swanson K, Wu X, Zou J, Wu J. Next-Gen Therapeutics: Pioneering Drug Discovery with iPSCs, Genomics, AI, and Clinical Trials in a Dish. Annu Rev Pharmacol Toxicol 2025;65:71-90. [PMID: 39284102 PMCID: PMC12011342 DOI: 10.1146/annurev-pharmtox-022724-095035] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 01/24/2025]
46
Ojeh N, Vecin NM, Pastar I, Volk SW, Wilgus T, Griffiths S, Ramey‐Ward AN, Driver VR, DiPietro LA, Gould LJ, Tomic‐Canic M. The Wound Reporting in Animal and Human Preclinical Studies (WRAHPS) Guidelines. Wound Repair Regen 2025;33:e13232. [PMID: 39639458 PMCID: PMC11621255 DOI: 10.1111/wrr.13232] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/19/2024] [Revised: 10/02/2024] [Accepted: 10/28/2024] [Indexed: 12/07/2024]
47
Coll RC, Schroder K. Inflammasome components as new therapeutic targets in inflammatory disease. Nat Rev Immunol 2025;25:22-41. [PMID: 39251813 DOI: 10.1038/s41577-024-01075-9] [Citation(s) in RCA: 23] [Impact Index Per Article: 23.0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 07/24/2024] [Indexed: 09/11/2024]
48
Gregory DJ, Han F, Li P, Gritsenko MA, Kyle J, Riley FE, Chavez D, Yotova V, Sindeaux RHM, Hawash MBF, Xu F, Hung LY, Hayden DL, Tompkins RG, Lanford RE, Kobzik L, Hellman J, Jacobs JM, Barreiro LB, Xiao W, Warren HS. Molecular profiles of blood from numerous species that differ in sensitivity to acute inflammation. Mol Med 2024;30:280. [PMID: 39730996 DOI: 10.1186/s10020-024-01052-x] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/01/2024] [Accepted: 12/18/2024] [Indexed: 12/29/2024]  Open
49
Jamiyansharav M, Shin H, Kim B, Kim H, Han SJ, Seong JK, Suh JG, Seo KY. Characteristic visual phenotypes in Korean wild mice (KWM/Hym). Lab Anim Res 2024;40:42. [PMID: 39716311 DOI: 10.1186/s42826-024-00230-6] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/08/2024] [Revised: 11/11/2024] [Accepted: 11/21/2024] [Indexed: 12/25/2024]  Open
50
Fuadah Y, Pramudito MA, Firdaus L, Vanheusden FJ, Lim KM. QSAR Classification Modeling Using Machine Learning with a Consensus-Based Approach for Multivariate Chemical Hazard End Points. ACS OMEGA 2024;9:50796-50808. [PMID: 39741811 PMCID: PMC11683616 DOI: 10.1021/acsomega.4c09356] [Citation(s) in RCA: 4] [Impact Index Per Article: 4.0] [Reference Citation Analysis] [Abstract] [Grants] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 10/14/2024] [Revised: 11/15/2024] [Accepted: 12/03/2024] [Indexed: 01/03/2025]
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