Editorial
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastrointest Oncol. Jan 15, 2012; 4(1): 1-8
Published online Jan 15, 2012. doi: 10.4251/wjgo.v4.i1.1
Table 1 Main characteristics of the studies published on allele-specific expression of transforming growth factor β receptor 1 and colorectal cancer risk
StudyMajority populationSampleMethodAllelic markersInformative cases/controlsASE (binary) cases/controlsASE higher in CRC cases
BinaryContinuous
Valle et al[73] 2008CaucasianBloodSNaPshotrs334348138/105221.0%/2.9%YesYes
rs7871490
rs334349
rs1590
Guda et al[74] 2009CaucasianLymph. cell linePyroseqrs868Familial: 46/1734.3%/0%No
Normal colonrs334348Sporadic: 44/030%/-
rs334349
rs420549
rs1590
Carvajal-Carmona et al[66] 2010CaucasianLymph. cell lineGenescan*6A/9AFamilial: 24/45329.2%/26.7%NoNo
SNaPshotrs1590
Pasche et al[75] 2010CaucasianLymph. cell lineSNaPshotrs33434874/0314.9%/-Yes
rs7871490
rs334349
rs1590
Tomsic et al[76] 2010CaucasianBloodPyroseqrs8681109/12531.8%/1.6%NoYes
rs334348246.8%/31.2%
rs334349
rs420549
rs1590
Seguí et al[77] 2011CaucasianNormal colonPyroseqrs334349171/9030%/2.2%NoNo
AshkenaziLymphocytesrs785089522.3%/2.2%
rs420549
rs1590
Abadie et al[78] 2011CaucasianBloodSNaPshotrs33434869/9830%/0%NoNo
rs7871490
rs334349
rs1590