Effects of general anesthesia plus ropivacaine transversus abdominis plane block on analgesia and organ protection in colorectal cancer surgery

Table 1 Baseline data of included patients, n (%)/mean ± SD

Factors	Control group (n = 85)	Combination group (n = 123)	χ2/t	P value
Age (year)	59.95 ± 9.08	57.74 ± 8.28	1.820	0.070
Sex			0.160	0.689
Male	48 (56.47)	66 (53.66)
Female	37 (43.53)	57 (46.34)
BMI (kg/m2)	21.67 ± 2.00	21.54 ± 2.04	0.437	0.663
TNM stage			0.088	0.767
Stage II	46 (54.12)	64 (52.03)
Stage III	39 (45.88)	59 (47.97)
ASA classification			0.141	0.707
Class I	41 (48.24)	55 (44.72)
Class II	44 (51.76)	68 (55.28)
Family history of CRC			0.074	0.785
Yes	8 (9.41)	13 (10.57)
No	77 (90.59)	110 (89.43)
Place of residence			0.703	0.402
Rural areas	49 (57.65)	78 (63.41)
Urban areas	36 (42.35)	45 (36.59)

BMI: Body mass index; TNM: Tumor-node-metastasis; ASA: American Society of Anesthesiologists; CRC: Colorectal cancer.

Table 2 Comparison of complications between the two groups, n (%)

	Control group (n = 85)	Combination group (n = 123)	χ2	P value
Nausea and vomiting	9 (10.59)	4 (3.25)	-	0.0321
Respiratory depression	0 (0.00)	0 (0.00)	-	-
Delayed recovery	0 (0.00)	4 (3.25)	-	0.0931
Postoperative delirium	0 (0.00)	0 (0.00)	-	-
Urinary retention	6 (7.06)	4 (3.25)	1.592	0.207
Overall complications	14 (16.47)	12 (9.76)	2.072	0.150

¹Owing to expected frequencies of < 5, Fisher’s exact test was used to calculate the P-value.

Table 3 Multiple linear regression analysis of factors influencing visual analog scale score at 24 hours post-operatively

	Unstandardized coefficient (β)	SE	Standardized coefficient (β)	t value	P value
Constant	2.487	0.274	-	9.072	< 0.001
Anesthesia regimen	-1.633	0.077	-0.816	-21.293	< 0.001
Age (years)	0.003	0.002	0.034	1.876	0.062
BMI (kg/m2)	0.016	0.007	0.040	2.266	0.024
Time of first flatus (hours)	-0.001	0.002	-0.029	-0.655	0.513
IL-6 (pg/mL)	-0.001	0.001	-0.039	-1.647	0.101

BMI: Body mass index; IL-6: Interleukin-1.