Solitary esophageal metastasis ten years after curative resection of stage I rectal adenocarcinoma: A case report

Table 1 A mini review summarizing reported esophageal metastases from colorectal carcinoma

No.	Ref.	Interval	Primary site/stage	Esophageal site/pattern	Diagnostic method	Treatment	Outcome
1	Kagaya et al[6]	14 months	Cecal adenocarcinoma/stage IV	Lower esophagus/submucosal tumor	Histology	Palliative stent + bypass surgery	Well 6 months after surgery
2	Watanabe et al[7]	3 years	Rectal adenocarcinoma/stage IIIB	Mid-thoracic esophagus/submucosal tumor	Biopsy + IHC	FOLFOX + bevacizumab	Died 16 months after recurrence
3	Sönmez et al[8]	Synchronous	Rectal adenocarcinoma/stage IV	Polypoid esophageal lesion	Biopsy + IHC	Plan to surgery after radiation radiotherapy to the rectum	NR
4	Tanaka et al[2]	1 year	Cecal signet-ring cell carcinoma/stage I	Multiple longitudinal submucosal tumors	Biopsy + IHC	FOLFOX + bevacizumab	Died 1 year and 5 months after surgery
5	Thomasset et al[9]	1 year	Sigmoid carcinoma/Dukes C	Lower esophagus/polypoidal lesion	Histology	5fluorouracil + folinic acid	Died six months after metastases
6	Bhurgri et al[10]	3 years	Sigmoid colon carcer/stage IIB	Esophageal lesion	Biopsy + IHC	Gastrostomy tube + FOLFOX	NR
7	Vashi et al[11]	4 years	Colon carcinoma/stage III	Gastroesophageal junction and mid esophagus/ multiple nodules	Histological and immunostains	Irinotecan + cetuximab	NR
8	Lohsiriwat et al[12]	1 year	Rectal carcinoma/stage IV	Proximal esophagus/ a 4-mm sessile polyp	Biopsy	Supportive therapy	Died 2 months later
9	This study	10 years	Rectal adenocarcinoma/stage I	Mid-thoracic esophagus/submucosal involvement	Biopsy + IHC + KNPB gene test	VMAT + CAPOX + cetuximab	Partial response at 3 months

VMAT: Volumetric modulated arc therapy; IHC: Immunohistochemistry; CAPOX: Capecitabine and oxaliplatin; NR: Not reported.