Erythropoietin-induced hepatocyte receptor A2 regulates effect of pyroptosis on gastrointestinal colorectal cancer occurrence and metastasis resistance

Table 1 Summary of various erythropoietin-induced hepatocyte receptor and their implicated roles depending on cancer type

Cancer type	Eph receptor	Aberrant function	Role of Eph receptor
Colorectal cancer	EphA1	Overexpressed in early stages; low expression in later stages	Tumour suppressive
	EphA2	Overexpressed in early stages; low expression in later stages	Tumour suppressive
	EphA3	Low expression	Tumour suppressive
	EphA4	Overexpressed	Tumour promoting
	EphA7	Low expression	Tumour suppressive
	EphB2	Overexpressed in early stages; low expression in later stages	Tumour suppressive
	EphB3	Overexpressed in early stages; low expression in later stages	Tumour suppressive
	EphB4	Overexpressed	Tumour promoting
	EphB6	Low expression	Tumour suppressive

Eph: Erythropoietin-induced hepatocyte.