Retrospective Cohort Study
Copyright ©The Author(s) 2024.
World J Gastrointest Oncol. Mar 15, 2024; 16(3): 750-760
Published online Mar 15, 2024. doi: 10.4251/wjgo.v16.i3.750
Table 1 Comparison of baseline clinical and endoscopic characteristics of chicken skin mucosa-positive colorectal polyps

Juvenile polyps (n = 5)
Neoplastic polyps (n = 70)
NHGN (n = 86)
SM stage cancer (n = 22)
P value
Age (mean SD, yr) (n = 177)26.66 8.1758.68 9.1561.26 11.1264.4 8.73< 0.001
diameter (cm) (n = 183)1.57 0.340.88 0.371.61 0.521.93 0.53< 0.001
Sex (n = 177)Male43346150.34
Female131407
Location (n = 183)Left colon24850120.38
Rectum3223610
Morphology (n = 183)Polypoid (Is, Isp, Ip)55775180.63
Nonpolypoid (IIa, LST)013114
CSMType 15255917< 0.001
Type 2045275
Table 2 Comparison of the endoscopic features of risk factors for malignant transformation of chicken skin mucosa-positive neoplastic polyps on white light endoscopy
Endoscopic features
Neoplastic polyps (n = 70)
NHGN (n = 86)
P value
Multilobulated20400.03
Round and smooth54210.00
Deeper red mucosal color11540.00
Granulated surface260.55
Table 3 Comparison of endoscopic features of invasion depth of chicken skin mucosa-positive early colorectal cancer with white light endoscopy
Endoscopic features
NHGN (n = 86)
SM stage cancer (n = 22)
P value
Ulceration or errhysis (all)230.08
Demarcated depressed area (all)314< 0.001
Deeper red mucosal color (all)54160.25
Stalk swelling (P)730.65
Fullness (P)1240.81
Table 4 Logistic regression analyses of endoscopic risk features for malignant transformation of chicken skin mucosa-positive neoplastic polyps
Variable
OR (95%CI)
P value
Diameter (≥ 10/< 10 mm)15.84 (5.01–50)0.00
CSM (type ½)0.56 (0.23–1.36)0.20
Multilobulated0.4 (0.13–1.22)0.11
Deeper red mucosal color3.5 (1.25–9.82)0.02
Table 5 Logistic regression analyses of endoscopic risk features for early submucosal invasion of chicken skin mucosa-positive colorectal cancer
Variable
OR (95%CI)
P value
CSM (type ½)1.63 (0.37–7.14)0.52
Ulcer bleeding1.68 (0.08–37.06)0.74
Demarcated depressed area78.03 (13.04–466.94)0.00
Diameter (≥ 10/< 10 mm)1.28 (0.14–11.67)0.83
Table 6 Type of chicken skin mucosa endoscopic resection in different subgroups

Juvenile polyps (n = 5)
Neoplastic polyps (n = 70)
NHGN (n = 81)
SM stage cancer (n = 7)
P value
Complete resection0302620.194
Partial resection540555