Retrospective Study
Copyright ©The Author(s) 2021.
World J Gastrointest Oncol. Jan 15, 2021; 13(1): 24-36
Published online Jan 15, 2021. doi: 10.4251/wjgo.v13.i1.24
Table 1 Patient characteristics (n = 48)
Characteristic
Patients
Age
< 60 yr 23
≥ 60 yr 25
Smoking history
Yes 26
No 22
Drinking history
Yes 26
No 22
Family history
Yes18
No30
Treament
Sugery48
Neoadjuvant chemotherapy 12
Adjuvant chemotherapy30
Adjuvant chemoradiotherapy4
Site of tumor
Upper5
Middle16
Lower27
Bormann classification
Type 1 3
Type 2 9
Type 3 20
Type 4 12
Lauren’s classification
Type 1 9
Type 222
Type 313
Pathological N factor
0-3a 25
3b 23
Pathological T factor
0-3 8
4a-4b38
Table 2 Neoadjuvant chemotherapy
Neoadjuvant chemotherapy regimen
Patients
SOX5
DOS1
XELOX1
PTX + L-OHP + S-12
Paclitaxel liposome + L-OHP + S-11
PTX + DDP + S-11
DXT + S-1/5-Fu + L-OHP + CPT-111
Table 3 Types of surgery
Surgery type
Patients
Laparoscopic assist distal gastrectomy + D216
Laparoscopic assist total gastrectomy + D29
Traditional distal gastrectomy + D211
Traditional total gastrectomy + D210
Laparoscopic assisted proximal gastrectomy + splenectomy + D21
Laparoscopic assisted proximal gastrectomy + D21
Table 4 Adjuvant chemotherapy
Adjuvant chemotherapy regimen
Patients
SOX12
SOX + radiotherapy4
XELOX3
Paclitaxel liposome + L-OHP + S-1
S-12
PTX + 5-Fu + L-OHP1
DXT + S-11
PTX + CAP 1
DXT + L-OHP + CAP1
S-1 + DDP2
Unknown6
Table 5 Univariate analysis of the risk factors for overall survival
Patient characteristic

OR
95%CI
P value
Age0.588
< 60 yr231.000
≥ 60 yr250.8220.404-1.671
Smoking history0.935
Yes261.000
No 220.9710.476-1.979
Drinking history0.137
Yes 261.000
No 221.7260.841-3.540
Site of tumor0.021
Upper/Middle211.000
Lower270.4270.207-0.880
Signet-ring cell0.229
Yes191.000
No 280.6400.309-1.325
Bormann classification0.416
Type1/2/3 321.000
Type4 121.4310.603-3.392
Lauren’s classification0.080
Type 191.000
Type 2/Type 3352.5880.892-7.508
Pathological N factor0.001
0-3a 241.000
3b224.1941.870-9.406
Pathological T factor0.028
0-3 91.000
4a-4b375.0081.190-21.072
Vascular invasion0.046
Negative121.000
Positive342.5541.017-6.413
CA1990.002
Elevate 131.000
Normal 310.2670.118-0.604
CEA0.837
Elevated 13
Normal320.9170.403-2.089
Therapy0.112
Surgery along12
Combined therapy 360.5400.252-1.154
Table 6 Multivariate analysis of the risk factors for overall survival (N = 39, n = 25)
Patient characteristic

OR
95%CI
P value
Site of tumor0.105
Upper/Middle 18
Lower21
Lauren’s classification0.476
Type 18
Type 2/Type 331
Pathological N factor 0.001
0-3a191.000
3b205.3651.971-14.609
Pathological T factor0.146
0-39
4a-4b30
Vascular invasion0.031
Negative101.000
Positive293.6601.124-11.917
CA199
Elevated120.789
Normal 27