Sessile serrated adenoma detection rate is correlated with adenoma detection rate

Table 1 Patient characteristics

	Total (n = 3691)
Age, mean ± SD (yr)	63.5 ± 13.3
Sex: Male (%)	2224 (60.3)
Adequate bowel cleansing (%)	3585 (97.1)
Cecal intubation rate (%)	3636 (98.5)
Indications for colonoscopy (%)
Surveillance	1314 (35.6)
Fecal occult blood test	538 (14.6)
Screening for other symptoms	544 (14.7)
Others	1295 (35.1)

Others include screening before surgery or chemotherapy, patients’ desire, and so on.

Table 2 Gastroenterologist characteristics

	n = 35
Sex: Male (%)	25/35 (71.4)
Years of experience in colonoscopy (%)
5-9	24/35 (68.6)
10-14	6/35 (17.1)
≥ 15	5/35 (14.3)
Number of colonoscopies performed (%)
≤ 100	19/35 (54.3)
100-200	10/35 (28.6)
≥ 200	6/35 (17.1)
Withdrawal time: Mean (SD), m	10.1 ± 6.9

Table 3 Odds ratio estimates from logistic generalized estimating equations for adenoma detection

Variable	Univariable model		Multivariable model
	OR (95%CI)	P	OR (95%CI)	P
Patient-level variable
Age (yr)	1.02 (1.02, 1.03)	< 0.001	1.02 (1.02, 1.03)	< 0.001
Female	0.63 (0.55, 0.71)	< 0.001	0.61 (0.54, 0.70)	< 0.001
Non-adequate bowel cleansing	0.36 (0.22, 0.57)	< 0.001	0.32 (0.19, 0.52)	< 0.001
Endoscopist-level variable
Endoscopist's experiment (yr)	0.98 (0.94, 1.02)	0.36	0.99 (0.96, 1.02)	0.55
Mean withdrawal time ≥ 8 min (vs < 8 min)	1.72 (1.23, 2.41)	0.0015	1.77 (1.28, 2.46)	< 0.001

Multivariable model simultaneously adjusted for listed variables. Confidence intervals and P-values were calculated by robust variance specifying a gastroenterologist as a cluster.

Table 4 Odds ratio estimates from logistic generalized estimating equations for sessile serrated adenoma detection

Variable	Univariable model		Multivariable model
	OR (95%CI)	P	OR (95%CI)	P
Patient-level variable
Adenoma detection (vs none)	2.44 (1.45, 4.09)	< 0.001	2.53 (1.53, 4.20)	< 0.001
Age (yr)	0.99 (0.98, 1.01)	0.27	0.99 (0.98, 1.00)	0.07
Female	1.28 (0.77, 2.11)	0.34	1.40 (0.85, 2.29)	0.19
Non-adequate bowel cleansing	0.50 (0.07, 3.47)	0.48	0.60 (0.08, 4.28)	0.61
Endoscopist-level variable
Endoscopist's experiment (yr)	0.99 (0.89, 1.10)	0.86	1.00 (0.91, 1.09)	0.96
Mean withdrawal time ≥ 8 min (vs < 8 min)	1.74 (0.70, 4.29)	0.23	1.53 (0.62, 3.75)	0.35

Multivariable model simultaneously adjusted for listed variables.