Gural Z, Saglam S, Yucel S, Kaytan-Saglam E, Asoglu O, Ordu C, Acun H, Sharifov R, Onder S, Kizir A, Oral EN. Neoadjuvant hyperfractionated accelerated radiotherapy plus concomitant 5-fluorouracil infusion in locally advanced rectal cancer: A phase II study. World J Gastrointest Oncol 2018; 10(1): 40-47 [PMID: 29375747 DOI: 10.4251/wjgo.v10.i1.40]
Corresponding Author of This Article
Dr. Zeynep Gural, MD, Attending Doctor, Department of Radiation Oncology, Acibadem University Medical Faculty, Halkalı Merkez Mahallesi, Turgut Özal Blv No:16, Istanbul 34303, Turkey. zeynep.gural@acibadem.com.tr
Research Domain of This Article
Oncology
Article-Type of This Article
Clinical Practice Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Tumor control/acute normal tissue complication probability
Late normal tissue complication probability
Bed (Gy) (α/β = 10 Gy)
Bed (Gy) (α/β = 3 Gy)
Regimen
No time correction
With time correction
25 Gy/5 fr/5 d (d = 5 Gy)
37.5
37.5
66.7
50 Gy/25 fr/33 d (d = 2 Gy)
60.0
44.4
83.4
42 Gy/28 fr/18 d (d = 1.5 Gy)
48.3
41.7
63.0
Citation: Gural Z, Saglam S, Yucel S, Kaytan-Saglam E, Asoglu O, Ordu C, Acun H, Sharifov R, Onder S, Kizir A, Oral EN. Neoadjuvant hyperfractionated accelerated radiotherapy plus concomitant 5-fluorouracil infusion in locally advanced rectal cancer: A phase II study. World J Gastrointest Oncol 2018; 10(1): 40-47