Correction to: Prohibitin 1 inhibits cell proliferation and induces apoptosis via the p53-mediated mitochondrial pathway in vitro

Abstract

Correction to “Prohibitin 1 inhibits cell proliferation and induces apoptosis via the p53-mediated mitochondrial pathway in vitro. World J Gastrointest Oncol 2024; 16(2): 398-413 [PMID: 38425403 DOI: 10.4251/wjgo.v16.i2.398]”. In this article, Figures 4E and F, and 6I need to be corrected.

Key Words: World Journal of Gastrointestinal Oncology; Correction

Core Tip: This manuscript is to add a correction note to “Prohibitin 1 inhibits cell proliferation and induces apoptosis via the p53-mediated mitochondrial pathway in vitro. World J Gastrointest Oncol 2024; 16(2): 398-413 [PMID: 38425403 DOI: 10.4251/wjgo.v16.i2.398]”.

CORRECTION

In this correction, we aim to address specific errors that were identified in our recently published manuscript titled “Prohibitin 1 inhibits cell proliferation and induces apoptosis via the p53-mediated mitochondrial pathway in vitro” in the World Journal of Gastrointestinal Oncology[1]. Regarding the errors that occurred, the following changes have specifically been made to Figures 4E and F, and 6I (Figure 1 and Supplementary material):

Figure 1 Corrected figure. A: Corrected Figure 4E; B: Corrected Figure 4F; C: Corrected Figure 6I.

For Figure 4E, an image placement error occurred during manuscript preparation due to the identical photographic backgrounds used for the protein expression analyses of p21 and PHB1. As a result, the PHB1 image was incorrectly presented in place of the p21 image. After careful examination of the original data, we confirmed that the statistics were accurate, and each protein experiment was repeated three times. The original image has now been replaced with the correct p21 protein image. This error was solely due to image misplacement and did not affect the scientific validity or conclusions of the paper (Figure 1A). Similarly, in figure 6I, the expression of the Bax protein across different cells was also photographed against the same background, leading to the same type of error as described above. The raw data for this experiment, which was repeated three times, were reviewed, and the original image has now been replaced with the correct Bax protein image (Figure 1C). In addition, concerns were raised regarding the visual similarity between the Cyclin E1 and β-actin bands in Figure 1B. To ensure the scientific integrity and clarity of the article, the original data were meticulously reviewed. We confirmed the accuracy of the Cyclin E1 image and selected a new image for β-actin to clearly distinguish between the two bands. Both images were derived from the same experimental conditions involving PHB1 knockdown (Figure 1B). These corrections do not affect the scientific validity or the conclusions of the original manuscript.

The error was discovered by reader feedback on May 25, 2025. When we first received feedback from readers, we reviewed the original data of the trial and finally determined that an error was indeed caused by our own carelessness. Therefore, we immediately contacted the magazine office and wrote a correction report, hoping to correct the error in time. We apologize for the error in the article[1]. The correction ensures accuracy and scientific integrity.