S-1 induced hepatic steatosis in patients with pancreatic cancer: Retrospective analysis

Figure 1 Abdominal computed tomography scans of a pancreatic cancer patient before (A) and during treatment (B) with S-1, showing that the liver/spleen ratio decreased after start of treatment.

Figure 2 Median liver/spleen ratios in pancreatic cancer patients before and after treatment with S-1. The ratio decreased significantly, from 1.27 before treatment to 1.09 after S-1 treatment (P = 0.012).

Figure 3 Correlation between liver/spleen ratio and alanine transaminase activity in pancreatic cancer patients treated with S-1. A significant inverse correlation was observed between these parameters (r = -0.417, P < 0.027).