Paradoxical expression pattern of the epithelial mesenchymal transition-related biomarkers CD44, SLUG, N-cadherin and VSIG1/Glycoprotein A34 in gastrointestinal stromal tumors

doi:10.4251/wjgo.v9.i11.436

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Nov 15, 2017; 9(11): 436-443
Published online Nov 15, 2017. doi: 10.4251/wjgo.v9.i11.436

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Figure 1 Immunohistochemical profile of gastrointestinal stromal tumors (× 20). A: Cytoplasmic expression of N-cadherin; B: Cytoplasmic expression of CD44; C: Membrane positivity of CD44.

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Figure 2 Subcellular localization of the immunohistochemical markers (nuclear and/or cytoplasmic) in gastrointestinal stromal tumors (× 20). A, B: SLUG; C, D: V set and immunoglobulin domain containing 1 (VSIG1).

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Figure 3 Kaplan Meier survival analysis in gastrointestinal stromal tumors. Immunoexpression of some epithelial mesenchymal/mesenchymal epithelial transition-related markers influences the overall survival.

Citation: Kövecsi A, Gurzu S, Szentirmay Z, Kovacs Z, Bara TJ, Jung I. Paradoxical expression pattern of the epithelial mesenchymal transition-related biomarkers CD44, SLUG, N-cadherin and VSIG1/Glycoprotein A34 in gastrointestinal stromal tumors. World J Gastrointest Oncol 2017; 9(11): 436-443
URL: https://www.wjgnet.com/1948-5204/full/v9/i11/436.htm
DOI: https://dx.doi.org/10.4251/wjgo.v9.i11.436